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US4293496A Expired / Lapsed US ⏱️ 0.0 years remaining

6(R)-[2-(8-Hydroxy-2,6-dimethylpolyhydronaphthyl-1)-ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones

Assignee: Merck and Co Inc
•
Filing: 1980-08-05
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Granted: 1981-10-06
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Expires: 2000-08-05
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Abstract

Abstract The title compounds are prepared by saponifying the corresponding 8-acyloxy compounds, with strong base at elevated temperatures to remove the hindered acyl group without disrupting the rest of the molecule. The products are useful as intermediates in the synthesis of antihypercholesterolemia agents.

Inventors

  • 👤 Alvin K. Willard

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 09:46
CPC Classifications
C; C07; C07D; C07D309/00; C07D309/16; C07D309/28; C07D309/30

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 41 words
A compound of the formula ##STR38## in which the dotted lines X, Y and Z represent possible double bonds, said double bonds, when any are present, being either X and Z in combination or one of X, Y or Z alone.
Claim 2
Dependent Claim 41 words
A compound of the formula ##STR38## in which the dotted lines X, Y and Z represent possible double bonds, said double bonds, when any are present, being either X and Z in combination or one of X, Y or Z alone.
Claim 3
Dependent Claim 13 words
A compound of claim 1 in which X and Z represent double bonds.
Claim 4
Dependent Claim 12 words
A compound of claim 1 in which X is a double bond.
Claim 5
Dependent Claim 12 words
A compound of claim 1 in which Y is a double bond.
Claim 6
Dependent Claim 12 words
A compound of claim 1 in which Z is a double bond.
Claim 7
Dependent Claim 17 words
A compound of claim 1 in which none of X, Y or Z is a double bond.

References Cited (Backward Citations)

US3983140A Cited
US4049495A Cited
US4137322A Cited
US4255444A Cited
US4231938A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1984-10-05 1985-04-06 1985-10-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1988-10-05 1989-04-06 1989-10-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1992-10-05 1993-04-06 1993-10-06 $7700.00 Window Closed / Lapsed

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