US4292250A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Vitamin D derivatives
Assignee: Wisconsin Alumni Research Foundation
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Filing: 1980-11-17
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Granted: 1981-09-29
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Expires: 2000-11-17
Abstract
Abstract The invention provides new 25-hydroxy vitamin D2 25-glucuronide derivatives among which is 25-hydroxy vitamin D2 25-D-glucuronic acid. By virtue of the structural similarity of 25-hydroxy vitamin D2 25-D-glucuronic acid to 25-hydroxy vitamin D2, a known biologically potent compound, the glucuronic acid compound should be a ready substitute for 25-hydroxy vitamin D2 in various therapeutic applications and particularly where the water solubility of the glucuronic acid compound is a necessity or advantage.
Inventors
- 👤 Hector F. DeLuca
- 👤 Heinrich K. Schnoes
- 👤 Leon W. LeVan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 14:48
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/18
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
26 words
Compounds having the formula ##STR2## where R is a hydrogen or methyl, R 1 is trimethylsilyl or acetyl and R 2 is hydrogen, trimethylsilyl or acetyl.
Claim 2
Dependent Claim
26 words
Compounds having the formula ##STR2## where R is a hydrogen or methyl, R 1 is trimethylsilyl or acetyl and R 2 is hydrogen, trimethylsilyl or acetyl.
Claim 3
Dependent Claim
6 words
25-hydroxy vitamin D 2 25-D-hexuronic acid.
Claim 4
Dependent Claim
6 words
25-hydroxy vitamin D 2 25-D-hexuronic acid.
Claim 5
Dependent Claim
5 words
25-hydroxy vitamin D 2 25-β-D-glucuronide.
Claim 6
Dependent Claim
5 words
25-hydroxy vitamin D 2 25-β-D-glucuronide.
References Cited (Backward Citations)
US4119647A
Cited
US4230627A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-09-28 | 1985-03-30 | 1985-09-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-09-28 | 1989-03-30 | 1989-09-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-09-28 | 1993-03-30 | 1993-09-29 | $7700.00 | Window Closed / Lapsed |