Patent US4260579A successfully refreshed from Google Patents.
US4260579A
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Device and method for simulating bilirubin in urine
Assignee: Bayer Corp
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Filing: 1979-05-10
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Granted: 1981-04-07
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Expires: 1999-05-10
Abstract
Abstract A device and method are disclosed for preparing a bilirubin-containing control solution. The device comprises a carrier vehicle having incorporated with it unconjugated bilirubin and certain dyes. Upon contact with a predetermined quantity of water a control solution results, which will simulate a pathological specimen of conjugated bilirubin-containing solution, upon analysis.
Inventors
- 👤 Nancy K. Barton
- 👤 Carmine M. Greene
- 👤 Myron C. Rapkin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 16:01
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/96; G01N33/72; G01N33/728; Y; Y10; Y10T; Y10T436/00; Y10T436/10; Y10T436/103332; Y10T436/14; Y10T436/145555; Y10T436/146666
Claims Analysis
Total Claims: 26
Claim 1
Independent Claim
34 words
A device useful in the preparation of a bilirubin control solution, said device comprising a carrier vehicle incorporated with a predetermined quantity of unconjugated bilirubin and a mixture of red, blue and yellow dyes.
Claim 2
Independent Claim
34 words
A device useful in the preparation of a bilirubin control solution, said device comprising a carrier vehicle incorporated with a predetermined quantity of unconjugated bilirubin and a mixture of red, blue and yellow dyes.
Claim 3
Dependent Claim
22 words
The device of claim 1 wherein said dyes are present in a weight ratio of about 0.08-0.04 to 0.03-0.009 to 1, respectively.
Claim 4
Independent Claim
22 words
The device of claims 1 or 2 wherein said dyes are FD&C red #40, FD&C blue #1 and External D&C yellow #7.
Claim 5
Dependent Claim
16 words
The device of claim 3 wherein said weight ratio is about 0.06 to 0.01 to 1.
Claim 6
Independent Claim
47 words
A device useful in the preparation of a bilirubin control solution, said device comprising a support member having attached thereto a first carrier matrix incorporated with a predetermined quantity of unconjugated bilirubin, and a second carrier matrix incorporated with a mixture of red, blue and yellow dyes.
Claim 7
Independent Claim
47 words
A device useful in the preparation of a bilirubin control solution, said device comprising a support member having attached thereto a first carrier matrix incorporated with a predetermined quantity of unconjugated bilirubin, and a second carrier matrix incorporated with a mixture of red, blue and yellow dyes.
Claim 8
Dependent Claim
22 words
The device of claim 5 wherein said dyes are present in a weight ratio of about 0.08-0.04 to 0.03-0.009 to 1, respectively.
Claim 9
Independent Claim
22 words
The device of claims 5 or 6 wherein said dyes are FD&C red #40, FD&C blue #1, and External D&C yellow #7.
Claim 10
Dependent Claim
16 words
The device of claim 7 wherein said weight ratio is about 0.06 to 0.01 to 1.
Claim 11
Dependent Claim
29 words
A composition useful in the preparation of a bilirubin control solution, said composition comprising a predetermined quantity of unconjugated bilirubin and a mixture of red, blue and yellow dyes.
Claim 12
Dependent Claim
29 words
A composition useful in the preparation of a bilirubin control solution, said composition comprising a predetermined quantity of unconjugated bilirubin and a mixture of red, blue and yellow dyes.
Claim 13
Dependent Claim
22 words
The composition of claim 9 wherein said dyes are present in a weight ratio of about 0.08-0.04 to 0.03-0.009 to 1, respectively.
Claim 14
Dependent Claim
22 words
The composition of claims 9 or 10 wherein said dyes are FD&C red #40, FD&C blue #1, and External D&C yellow #7.
Claim 15
Dependent Claim
16 words
The composition of claim 11 wherein the weight ratio is about 0.06 to 0.01 to 1.
Claim 16
Independent Claim
23 words
A method for preparing a bilirubin control solution comprising immersing the device of claims 1 or 2 in a predetermined volume of water.
Claim 17
Dependent Claim
21 words
A method for preparing a bilirubin control solution, comprising immersing the device of claim 3 in a predetermined volume of water.
Claim 18
Dependent Claim
21 words
A method for preparing a bilirubin control solution, comprising immersing the device of claim 4 in a predetermined volume of water.
Claim 19
Dependent Claim
35 words
A method for preparing a bilirubin control solution, comprising the consecutive steps of immersing the device of claim 5 or 6 in a predetermined volume of water for a predetermined time, and removing said device.
Claim 20
Dependent Claim
33 words
A method for preparing a bilirubin control solution, comprising the consecutive steps of immersing the device of claim 7 in a predetermined volume of water for a predetermined time, and removing said device.
Claim 21
Dependent Claim
33 words
A method for preparing a bilirubin control solution, comprising the consecutive steps of immersing the device of claim 8 in a predetermined volume of water for a predetermined time, and removing said device.
Claim 22
Dependent Claim
79 words
A method for determining the accuracy of a bilirubin test instrument, said method comprising the consecutive steps of: (a) forming a bilirubin control solution with the device of claim 1, 2, 5 or 6; (b) examining said solution with a test instrument capable of producing a predetermined detectable response to said control solution; (c) observing the actual response to the solution produced by said instrument; and (d) compensating for any discrepancy between said predetermined response and said actual response.
Claim 23
Dependent Claim
75 words
A method for determining the accuracy of a bilirubin test instrument, said method comprising the consecutive steps of: (a) forming a bilirubin control solution with the device of claim 3; (b) examining said solution with a test instrument capable of producing a predetermined detectable response to said control solution; (c) observing the actual response to the solution produced by said instrument; and (d) compensating for any discrepancy between said predetermined response and said actual response.
Claim 24
Dependent Claim
75 words
A method for determining the accuracy of a bilirubin test instrument, said method comprising the consecutive steps of: (a) forming a bilirubin control solution with the device of claim 4; (b) examining said solution with a test instrument capable of producing a predetermined detectable response to said control solution; (c) observing the actual response to the solution produced by said instrument; and (d) compensating for any discrepancy between said predetermined response and said actual response.
Claim 25
Dependent Claim
75 words
A method for determining the accuracy of a bilirubin test instrument, said method comprising the consecutive steps of: (a) forming a bilirubin control solution with the device of claim 7; (b) examining said solution with a test instrument capable of producing a predetermined detectable response to said control solution; (c) observing the actual response to the solution produced by said instrument; and (d) compensating for any discrepancy between said predetermined response and said actual response.
Claim 26
Dependent Claim
75 words
A method for determining the accuracy of a bilirubin test instrument, said method comprising the consecutive steps of: (a) forming a bilirubin control solution with the device of claim 8; (b) examining said solution with a test instrument capable of producing a predetermined detectable response to said control solution; (c) observing the actual response to the solution produced by said instrument; and (d) compensating for any discrepancy between said predetermined response and said actual response.
References Cited (Backward Citations)
US3526479A
Cited
US3477818A
Cited
US3511607A
Cited
US3652222A
Cited
US3853466A
Cited
US3850576A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-04-06 | 1984-10-06 | 1985-04-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-04-06 | 1988-10-06 | 1989-04-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-04-06 | 1992-10-06 | 1993-04-07 | $7700.00 | Window Closed / Lapsed |