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Cephalosporin derivatives

Assignee: Meiji Seika Kaisha Ltd
•
Filing: 1979-03-13
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Granted: 1981-03-24
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Expires: 1999-03-13
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Abstract

Abstract Novel cephalosporin derivatives having formulae (V) and (III): <IMAGE> (V) and <IMAGE> (III) wherein R1, R2, R3, R4, R8 and A are defined as in the specification.

Inventors

  • 👤 Fumio Kai
  • 👤 Takashi Tsuruoka
  • 👤 Osamu Makabe
  • 👤 Shigeharu Inouye
  • 👤 Hitoshi Ikeda
  • 👤 Yuzo Kazuno
  • 👤 Shokichi Nakajima
  • 👤 Shigeo Seki
  • 👤 Taro Niida

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 13:52
CPC Classifications
C; C07; C07D; C07D501/00; C07D501/14; C07D501/16; C07D501/20; C07D501/24; C07D501/36; A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/54; A61K31/542; A61K31/545; A61P; A61P31/00; A61P31/04

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 32 words
A cephalosporin compound of the formula ##STR189## wherein R 1 represents a hydrogen atom or a hydroxy group, and R 8 represents a 5-carbamoyl-1,3,4-thiadiazol-2-yl or 1-methyl-1,2,3,4-tetrazol-5-yl group and pharmaceutically acceptable salts thereof.
Claim 2
Dependent Claim 32 words
A cephalosporin compound of the formula ##STR189## wherein R 1 represents a hydrogen atom or a hydroxy group, and R 8 represents a 5-carbamoyl-1,3,4-thiadiazol-2-yl or 1-methyl-1,2,3,4-tetrazol-5-yl group and pharmaceutically acceptable salts thereof.
Claim 3
Dependent Claim 20 words
A cephalosporin compound and a pharmaceutically acceptable salt thereof as claimed in claim 1 wherein the compound is 7-{D(-)-α-[2-hydroxy-6-(p-tolyl)pyridine-3-carbonylamino]phenylacetamido}-3-(5-carbamoyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acid.
Claim 4
Dependent Claim 20 words
A cephalosporin compound and a pharmaceutically acceptable salt thereof as claimed in claim 1 wherein the compound is 7-{D(-)-α-[2-hydroxy-6-(p-tolyl)pyridine-3-carbonylamino]-p-hydroxyphenylacetamido}-3-(5-carbamoyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acid.
Claim 5
Dependent Claim 20 words
A cephalosporin compound and a pharmaceutically acceptable salt thereof as claimed in claim 1 wherein the compound is 7-{D(-)-α-[2-hydroxy-6-(p-tolyl)pyridine-3-carbonylamino]-p-hydroxyphenylacetamido}-3-(1-methyl-1,2,3,4-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid.
Claim 6
Dependent Claim 20 words
A cephalosporin compound and a pharmaceutically acceptable salt thereof as claimed in claim 1 wherein the compound is 7-{D(-)-α[2-hydroxy-6-(p-tolyl)pyridine-3-carbonylamino]phenylacetamido}-3-(1-methyl-1,2,3,4-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid.

References Cited (Backward Citations)

US3948903A Cited
US4154831A Cited
US4053470A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1984-03-23 1984-09-22 1985-03-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1988-03-23 1988-09-22 1989-03-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1992-03-23 1992-09-22 1993-03-24 $7700.00 Window Closed / Lapsed

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