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US4234316A Expired / Lapsed US ⏱️ 0.0 years remaining

Device for delivering measured quantities of reagents into assay medium

Assignee: FMC Corp
•
Filing: 1979-04-02
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Granted: 1980-11-18
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Expires: 1999-04-02
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Abstract

Abstract Device for delivering precise measured quantities of a plurality of reagents with each reagent being incorporated in a device and each being water soluble. The device has a water impervious support secured to one or more faces of which are discrete and separate elements each containing water soluble or dispersible binder and dispersed therein a water soluble or dispersible reagent. The reagent of each element in the device is reactive with at least one constituent in an assay medium or with at least one other reagent on the device. The device is used by contacting it with the assay medium until the elements dissolve completely.

Inventors

  • 👤 Richard C. Hevey

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 16:27
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/525; C; C12; C12Q; C12Q1/00; Y; Y10; Y10S; Y10S435/00; Y10S435/81; Y10S436/00; Y10S436/903; Y10T; Y10T436/00; Y10T436/14; Y10T436/142222; Y10T436/143333; Y10T436/144444; Y10T436/145555; Y10T436/146666

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 171 words
A device for precise quantitative introduction of a plurality of reagents into a liquid aqueous assay medium; said device comprising a water-impervious solid support member which is chemically inert to the reagents and to the material to be assayed, secured to one or more faces of said support member two or more discrete and separate elements consisting essentially of carrier solid organic binder which is soluble or dispersible in water, and dispersed in said solid binder a measured quantity of water-soluble or dispersible reagent, the reagent in each said element being reactive with at least one reagent in another element or with at least one constituent in said assay medium, said support member being a stiff elongated member having one portion constructed and arranged as a handle for said device, and having said discrete elements secured to portions thereof removed from said handle, said handle facilitating contact of said discrete elements with liquid assay medium to permit each said reagent and binder to dissolve completely and be mixed in said medium.
Claim 2
Independent Claim 171 words
A device for precise quantitative introduction of a plurality of reagents into a liquid aqueous assay medium; said device comprising a water-impervious solid support member which is chemically inert to the reagents and to the material to be assayed, secured to one or more faces of said support member two or more discrete and separate elements consisting essentially of carrier solid organic binder which is soluble or dispersible in water, and dispersed in said solid binder a measured quantity of water-soluble or dispersible reagent, the reagent in each said element being reactive with at least one reagent in another element or with at least one constituent in said assay medium, said support member being a stiff elongated member having one portion constructed and arranged as a handle for said device, and having said discrete elements secured to portions thereof removed from said handle, said handle facilitating contact of said discrete elements with liquid assay medium to permit each said reagent and binder to dissolve completely and be mixed in said medium.
Claim 3
Dependent Claim 30 words
A device as claimed in claim 1 in which said support member is in the form of a sheet and said elements are secured to opposite faces of said sheet.
Claim 4
Dependent Claim 47 words
In the method of assaying a liquid aqueous assay medium by introducing precise quantities of reagents into said medium, the improvement which comprises introducing said reagents by contacting with said medium a device as claimed in claim 2 until each said element has dissolved or dispersed therein.
Claim 5
Dependent Claim 53 words
A device as claimed in claim 1 in which two or more of said elements are overlaid in the form of a stack, the bottommost one of which is secured to said support member, and comprising a layer of water-insoluble or water-soluble material interposed as a separator between adjacent elements of said stack.
Claim 6
Dependent Claim 38 words
In the method of assaying a liquid aqueous assay medium by introducing precise quantities of reagents into said medium, the improvement which comprises introducing said reagents by contacting with said medium a device as claimed in claim 4.
Claim 7
Dependent Claim 22 words
A device as claimed in claim 1 in which one of said elements dissolves in water at a different rate from another.
Claim 8
Dependent Claim 38 words
In the method of assaying a liquid aqueous assay medium by introducing precise quantities of reagents into said medium, the improvement which comprises introducing said reagents by contacting with said medium a device as claimed in claim 6.
Claim 9
Dependent Claim 36 words
A device as claimed in claim 1 in which said support member is in the form of a sheet and said elements are secured to the same face of said sheet spaced apart from each other.
Claim 10
Dependent Claim 38 words
In the method of assaying a liquid aqueous assay medium by introducing precise quantities of reagents into said medium, the improvement which comprises introducing said reagents by contacting with said medium a device as claimed in claim 8.
Claim 11
Dependent Claim 47 words
In the method of assaying a liquid aqueous assay medium by introducing precise quantities of reagents into said medium, the improvement which comprises introducing said reagents by contacting with said medium a device as claimed in claim 1 until each said element has dissolved or dispersed therein.
Claim 12
Dependent Claim 19 words
The method as claimed in claim 10 including the step of stirring said liquid medium with said support member.

References Cited (Backward Citations)

BE750849A Cited
US3935303A Cited
US4062652A Cited
US3975162A Cited
US4029758A Cited
US4046513A Cited
US4135884A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1983-11-18 1984-05-19 1984-11-18 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1987-11-18 1988-05-19 1988-11-18 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1991-11-18 1992-05-19 1992-11-18 $7700.00 Window Closed / Lapsed

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