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US4046513A Expired / Lapsed US ⏱️ 0.0 years remaining

Printed reagent test devices and method of making same

Assignee: Bayer Corp
•
Filing: 1976-06-30
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Granted: 1977-09-06
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Expires: 1996-06-30
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Abstract

Abstract A test device for determining the presence of a constituent in a sample, and a method for making it are disclosed. The test device comprises reactants (e.g. reagents, enzymes, etc.) incorporated with a carrier matrix such that when the device is wetted with a test sample, the reactants and the constituent react to produce a detectable response. The reactants are positioned separately from each other on the matrix in substantially, discrete, non-contacting areas. Hence, reactants are maintained substantially separate from each other until the test device is wetted with the sample.

Inventors

  • 👤 Leighton Clifford Johnson

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 00:43
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/521; B; B01; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/5023; B01L2200/00; B01L2200/12; B01L2200/16; B01L2300/00; B01L2300/08; B01L2300/0809; B01L2300/0825

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 69 words
In a test device for determining the presence of a constituent in a sample in which a carrier matrix is incorporated with a reagent system capable of interacting with the constituent to produce a detectable response, said system comprising at least two reactants, the improvement wherein at least two of the reactants are printed separately from each other in substantially discrete, non-contacting, substantially coplanar areas of the carrier matrix.
Claim 2
Dependent Claim 69 words
In a test device for determining the presence of a constituent in a sample in which a carrier matrix is incorporated with a reagent system capable of interacting with the constituent to produce a detectable response, said system comprising at least two reactants, the improvement wherein at least two of the reactants are printed separately from each other in substantially discrete, non-contacting, substantially coplanar areas of the carrier matrix.
Claim 3
Dependent Claim 24 words
The improvement of claim 1 in which the constituent is occult blood, one reactant is o-tolidine and another separately printed reactant is a peroxide.
Claim 4
Dependent Claim 21 words
The improvement of claim 1 in which the reactants are present on the matrix as a plurality of substantially discrete dots.
Claim 5
Dependent Claim 17 words
The improvement of claim 3 in which the dots are positioned in alternate rows of different reactants.
Claim 6
Dependent Claim 20 words
The improvement of claim 1 in which the reactants are present on the matrix as a plurality of parallel stripes.
Claim 7
Dependent Claim 14 words
The improvement of claim 5 in which the stripes alternately contain a different reactant.
Claim 8
Dependent Claim 46 words
A test device for the detection of a constituent in a bodily fluid comprising a carrier matrix having a surface, and a reagent system comprising at least two reactant materials, said materials being separately printed in discrete areas on said surface in substantially discrete, non-contacting relation.
Claim 9
Dependent Claim 46 words
A test device for the detection of a constituent in a bodily fluid comprising a carrier matrix having a surface, and a reagent system comprising at least two reactant materials, said materials being separately printed in discrete areas on said surface in substantially discrete, non-contacting relation.
Claim 10
Dependent Claim 22 words
The test device of claim 7 in which one of the printed reactant materials is an enzyme entrapped in a polymer matrix.
Claim 11
Dependent Claim 21 words
The test device of claim 7 in which one of the reactant materials is an enzyme covalently bound to a substrate.
Claim 12
Dependent Claim 15 words
The test device of claim 7 in which the discrete relation comprises a recurring pattern.
Claim 13
Dependent Claim 19 words
The test device of claim 7 in which the discrete relation comprises dots, and the carrier matrix is paper.
Claim 14
Dependent Claim 19 words
The test device of claim 7 in which the discrete relation comprises dots, and the carrier matrix is plastic.

References Cited (Backward Citations)

US3127281A Cited
US2249867A Cited
US3507269A Cited
US3788948A Cited
US3711252A Cited
US3859169A Cited
US3838012A Cited
US3964871A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-09-05 1981-03-07 1981-09-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-09-05 1985-03-07 1985-09-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-09-05 1989-03-07 1989-09-06 $7700.00 Window Closed / Lapsed

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