Patent US4201767A successfully refreshed from Google Patents.
US4201767A
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Viral liposome particle
Assignee: Merck and Co Inc
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Filing: 1978-11-08
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Granted: 1980-05-06
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Expires: 1998-11-08
Abstract
Abstract The outer membrane of influenza virus is attached to a liposome by two different techniques. In addition, one of the techniques allows the entrapment of intact virus, usually one virus per liposome. The techniques can be performed with either influenza virus A or B.
Inventors
- 👤 Wardle Fullerton
- 👤 Bohdan Wolanski
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:13
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/10; A61K9/127; A61K9/1271; A61K39/00; A61K39/12; A61K39/145; A61K2039/51; A61K2039/525; A61K2039/5252; A61K2039/555; A61K2039/55511; A61K2039/55555; C; C12; C12N; C12N2760/00; C12N2760/00011; C12N2760/16011; C12N2760/16111; C12N2760/16134; C12N2760/16211; C12N2760/16234; Y; Y10; Y10S; Y10S424/00; Y10S424/812
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
45 words
A spikoliposome particle comprising a liposome having attached to its outer surface the intact outer membrane layer of influenza virus having intact spikes attached by having been reacted with both a positively-charged fatty acid amine of from 12 to 20 carbon atoms and a phospholipid.
Claim 2
Dependent Claim
45 words
A spikoliposome particle comprising a liposome having attached to its outer surface the intact outer membrane layer of influenza virus having intact spikes attached by having been reacted with both a positively-charged fatty acid amine of from 12 to 20 carbon atoms and a phospholipid.
Claim 3
Dependent Claim
11 words
A liposome particle containing entrapped therein an intact whole influenza virus.
Claim 4
Dependent Claim
11 words
A liposome particle containing entrapped therein an intact whole influenza virus.
Claim 5
Dependent Claim
17 words
A spikoliposome according to claim 1 wherein the virus is influenza type A or influenza type B.
Claim 6
Dependent Claim
19 words
A liposome according to claims 1 or 2 wherein the virus is influenza type A or influenza type B.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-05-06 | 1983-11-05 | 1984-05-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-05-06 | 1987-11-05 | 1988-05-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-05-06 | 1991-11-05 | 1992-05-06 | $7700.00 | Window Closed / Lapsed |