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US4198407A
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Substituted 2-phenyl-1,2,4-triazine-3,5(2H,4H)-diones, and coccidiostatic agents containing same
Assignee: Hoechst AG
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Filing: 1978-05-16
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Granted: 1980-04-15
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Expires: 1998-05-16
Abstract
Abstract Novel substituted 2-phenyl-1,2,4-triazine-3,5-(2H,4H)-diones are described as well as a process for their manufacture. The novel compounds may be used as chemotherapeutics, especially as coccidiostatic agents.
Inventors
- 👤 Manfred Rosner
- 👤 Wolfgang Raether
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 22:45
CPC Classifications
C; C07; C07D; C07D253/00; C07D253/02; C07D253/06; C07D253/065; C07D253/07; C07D253/075; A; A61; A61P; A61P33/00; A61P33/02; C07C; C07C323/00
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
45 words
A substituted 2-phenyl-1,2,4-triazine-3,5-(2H,4H)-dione of the formula: ##STR16## wherein: R 2 is hydrogen or methyl, R 3 and R 4 are chlorine, Z is oxygen, sulfur, or SO, and m is 0 or 1, as well as the salts of these compounds with physiologically acceptable bases.
Claim 2
Dependent Claim
45 words
A substituted 2-phenyl-1,2,4-triazine-3,5-(2H,4H)-dione of the formula: ##STR16## wherein: R 2 is hydrogen or methyl, R 3 and R 4 are chlorine, Z is oxygen, sulfur, or SO, and m is 0 or 1, as well as the salts of these compounds with physiologically acceptable bases.
Claim 3
Dependent Claim
20 words
A compound according to claim 1 wherein said salt is selected from alkali metal, alkaline earth metal and ammonium salts.
Claim 4
Dependent Claim
19 words
A compound according to claim 1 wherein R 3 and R 4 represent chlorine in the 3- and 5-positions.
Claim 5
Dependent Claim
9 words
A compound according to claim 1 which is 2[3,5-dichloro-4-(4-methylthio-phenoxy)-phenyl]-1,2,4-triazine-3,5-(2H,4H)-dione.
Claim 6
Dependent Claim
9 words
A compound according to claim 1 which is 2-[3,5-dichloro-4-(4-methylsulfinyl-phenoxy)-phenyl]-1,2,4-triazine-3,5-(2H,4H)-dione.
Claim 7
Dependent Claim
9 words
A compound according to claim 1 which is 2-[3,5-dichloro-4-(4-methythio-phenylthio)-phenyl]-1,2,4-triazine-3,5-(2H,4H)-dione.
Claim 8
Dependent Claim
9 words
A compound according to claim 1 which is 2-[3,5-dichloro-4-(4-methylsulfinyl-phenylsulfinyl)-phenyl]-1,2,4-triazine-3,5-(2H,4H)-dione.
Claim 9
Dependent Claim
9 words
A compound according to claim 1 which is 2-[3,5-dichloro-4-(3-methyl-4-methylthio-phenoxy)-phenyl]-1,2,4-triazine-3,5-(2H,4H)-dione.
Claim 10
Dependent Claim
25 words
A composition useful in the treatment of coccidiosis comprising a pharmaceutically acceptable carrier and an effective amount of a compound as defined in claim 1.
Claim 11
Dependent Claim
22 words
A method of treating protozoal diseases by administering to a patient an effective amount of a compound as claimed in claim 1.
References Cited (Backward Citations)
US3912723A
Cited
US3896124A
Cited
FR2231378A1
Cited
FR2234298A1
Cited
US3883527A
Cited
US3883528A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-04-15 | 1983-10-15 | 1984-04-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-04-15 | 1987-10-15 | 1988-04-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-04-15 | 1991-10-15 | 1992-04-15 | $7700.00 | Window Closed / Lapsed |