Patent US4197312A successfully refreshed from Google Patents.
US4197312A
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US
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Alkali metal and alkaline earth metal salts of benzoylacetonitriles
Assignee: Wyeth Holdings LLC
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Filing: 1978-05-09
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Granted: 1980-04-08
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Expires: 1998-05-09
Abstract
Abstract This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the novel active ingredients of said compositions of matter being the pharmacologically acceptable cationic salts of benzoylacetonitrile, o-fluorobenzoylacetonitrile, m-fluorobenzoylacetonitrile, p-fluorobenzoylacetonitrile, or mixtures thereof.
Inventors
- 👤 Adolph E. Sloboda
- 👤 John W. Hanifin, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 13:56
CPC Classifications
C; C07; C07C; C07C255/00
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
48 words
The method of inhibiting the progression of arthritis in a mammal which comprises administering to said mammal an effective amount of a compound of the formula: ##STR4## wherein R is hydrogen or fluoro, M is a pharmacologically acceptable cation, and n is an integer from 1 to 3.
Claim 2
Independent Claim
48 words
The method of inhibiting the progression of arthritis in a mammal which comprises administering to said mammal an effective amount of a compound of the formula: ##STR4## wherein R is hydrogen or fluoro, M is a pharmacologically acceptable cation, and n is an integer from 1 to 3.
Claim 3
Independent Claim
47 words
The method of inhibiting progressive joint deterioration in a mammal which comprises administering to said mammal an effective amount of a compound of the formula: ##STR5## wherein R is hydrogen or fluoro, M is a pharmacologically acceptable cation, and n is an integer from 1 to 3.
Claim 4
Independent Claim
47 words
The method of inhibiting progressive joint deterioration in a mammal which comprises administering to said mammal an effective amount of a compound of the formula: ##STR5## wherein R is hydrogen or fluoro, M is a pharmacologically acceptable cation, and n is an integer from 1 to 3.
Claim 5
Independent Claim
45 words
The method of meliorating inflammation in a mammal which comprises administering to said mammal an effective amount of a compound of the formula: ##STR6## wherein R is hydrogen or fluoro, M is a pharmacologically acceptable cation, and n is an integer from 1 to 3.
Claim 6
Independent Claim
45 words
The method of meliorating inflammation in a mammal which comprises administering to said mammal an effective amount of a compound of the formula: ##STR6## wherein R is hydrogen or fluoro, M is a pharmacologically acceptable cation, and n is an integer from 1 to 3.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-04-08 | 1983-10-08 | 1984-04-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-04-08 | 1987-10-08 | 1988-04-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-04-08 | 1991-10-08 | 1992-04-08 | $7700.00 | Window Closed / Lapsed |