US4187284A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Skeletal imaging kit utilizing triethylene tetramine hexa (methylene phosphonic acid)
Assignee: Merck and Co Inc
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Filing: 1977-10-03
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Granted: 1980-02-05
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Expires: 1997-10-03
Abstract
Abstract This invention relates to a novel diagnostic kit for use in radiographic bone scanning. More particularly, it relates to a kit comprising ingredients employed in the preparation of an intravenous injection of a complex of Technetium-99m, stannous ion, and an organic phosphonate identified as triethylene tetramine hexa (methylene phosphonic acid).
Inventors
- 👤 Richard E. Rolleston
- 👤 Jacques A. Nadeau
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 15:38
CPC Classifications
A; A61; A61K; A61K51/00; A61K51/12; A61K51/1241; A61K2123/00
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
39 words
A kit for the preparation of an injectable solution incorporating Technetium 99m which comprises in a single sterile container a freeze-dried mixture of triethylene tetramine hexa (methylene phosphonic acid) or a water-soluble salt thereof and a water-soluble tin salt.
Claim 2
Dependent Claim
39 words
A kit for the preparation of an injectable solution incorporating Technetium 99m which comprises in a single sterile container a freeze-dried mixture of triethylene tetramine hexa (methylene phosphonic acid) or a water-soluble salt thereof and a water-soluble tin salt.
Claim 3
Dependent Claim
63 words
A kit for the preparation of an injectable solution incorporating Technetium 99m which comprises in a single sterile container a freeze-dried mixture of triethylene tetramine hexa (methylene phosphonic acid) or a water-soluble salt thereof and a water-soluble tin salt in a ratio by weight of from 10-100 parts of triethylene tetramine hexa (methylene phosphonic acid and 1 part of tin as stannous chloride.dihydrate.
Claim 4
Dependent Claim
63 words
A kit for the preparation of an injectable solution incorporating Technetium 99m which comprises in a single sterile container a freeze-dried mixture of triethylene tetramine hexa (methylene phosphonic acid) or a water-soluble salt thereof and a water-soluble tin salt in a ratio by weight of from 10-100 parts of triethylene tetramine hexa (methylene phosphonic acid and 1 part of tin as stannous chloride.dihydrate.
Claim 5
Dependent Claim
33 words
A kit in accordance with claim 2 in which the weight ratio of the components is 40 parts of triethylene tetramine hexa (methylene phosphonic acid) and 1 part of tin as stannous chloride.dihydrate.
Claim 6
Dependent Claim
33 words
A kit in accordance with claim 3 in which the triethylene tetramine hexa (methylene phosphonic acid) is present as the free acid and the tin is added in the form of stannous chloride.dihydrate.
Claim 7
Dependent Claim
10 words
The lead salt of triethylene tetramine hexa (methylene phosphonic acid).
Claim 8
Dependent Claim
10 words
The lead salt of triethylene tetramine hexa (methylene phosphonic acid).
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-02-04 | 1983-08-06 | 1984-02-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-02-04 | 1987-08-06 | 1988-02-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-02-04 | 1991-08-06 | 1992-02-05 | $7700.00 | Window Closed / Lapsed |