US4171432A
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Flavin adenine dinucleotide-iodothyronine conjugates
Assignee: Bayer Corp
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Filing: 1978-06-22
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Granted: 1979-10-16
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Expires: 1998-06-22
Abstract
Abstract Conjugates of the formula: <IMAGE> +TR <IMAGE> wherein Riboflavin-(Phos)2-Ribose represents the riboflavin-pyrophosphate-ribose residue in flavin adenine dinucleotide (FAD), n equals 2 through 6, Y is hydrogen or trifluoroacetyl, and beta 1 and beta 2 are, independently, hydrogen or iodine; and intermediates in the synthesis of such FAD conjugates. The FAD-iodothyronine conjugates, particularly where the iodothyronine is thyroxine, are useful as labeled conjugates in specific binding assays for determining the iodothyronine in liquid media such as serum.
Inventors
- 👤 Robert J. Carrico
- 👤 Richard D. Johnson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 12:52
CPC Classifications
C; C07; C07H; C07H21/00; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/74; G01N33/78
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
10 words
A compound of the formula: ##STR15## wherein n=2, through 6.
Claim 2
Dependent Claim
10 words
A compound of the formula: ##STR15## wherein n=2, through 6.
Claim 3
Dependent Claim
7 words
The compound of claim 1 wherein n=2.
Claim 4
Dependent Claim
7 words
The compound of claim 1 wherein n=6.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-10-15 | 1983-04-16 | 1983-10-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-10-15 | 1987-04-16 | 1987-10-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-10-15 | 1991-04-16 | 1991-10-16 | $7700.00 | Window Closed / Lapsed |