US4171204A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Precipitation of protein
Assignee: Abbott Laboratories
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Filing: 1978-09-01
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Granted: 1979-10-16
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Expires: 1998-09-01
Abstract
Abstract A method for analyzing blood serum or plasma wherein the blood serum or plasma is treated with about 1.4 or more volumes of acetonitrile, propionitrile, tetrahydrofuran or mixtures thereof to precipitate proteins and to provide a supernatant. The separated supernatant is subsequently examined for a component of interest.
Inventors
- 👤 Kathryn S. Schwenzer
- 👤 Susan E. Magic
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 16:14
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/483; G01N33/487; G01N33/49; G01N33/491; G01N33/50; Y; Y10; Y10S; Y10S530/00; Y10S530/827; Y10S530/829; Y10S530/83; Y10T; Y10T436/00; Y10T436/25; Y10T436/25125
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
67 words
In a method for analyzing blood serum or plasma wherein the blood serum or plasma is treated with an organic solvent to precipitate proteins and provide a supernatant followed by separating the supernatant and measuring a component in the supernatant, the improvement comprising treating a volume of blood plasma or serum with about 1.4 or more volumes of acetonitrile, propionitrile, tetrahydrofuran, or mixtures thereof to precipitate proteins.
Claim 2
Dependent Claim
67 words
In a method for analyzing blood serum or plasma wherein the blood serum or plasma is treated with an organic solvent to precipitate proteins and provide a supernatant followed by separating the supernatant and measuring a component in the supernatant, the improvement comprising treating a volume of blood plasma or serum with about 1.4 or more volumes of acetonitrile, propionitrile, tetrahydrofuran, or mixtures thereof to precipitate proteins.
Claim 3
Dependent Claim
67 words
In a method according to claim 1 for analyzing blood serum or plasma wherein the blood serum or plasma is treated with an organic solvent to precipitate proteins and provide a supernatant followed by separating the supernatant and measuring a component in the supernatant, the improvement comprising treating a volume of blood plasma or serum with about 1.4 or more volumes of acetonitrile to precipitate the proteins.
Claim 4
Independent Claim
33 words
A method for separating haptens from serum or plasma proteins comprising treating the serum or plasma with 1.4 or more volumes of acetonitrile, propionitrile, tetrahydrofuran or mixtures thereof and drawing off the supernatant.
Claim 5
Independent Claim
33 words
A method for separating haptens from serum or plasma proteins comprising treating the serum or plasma with 1.4 or more volumes of acetonitrile, propionitrile, tetrahydrofuran or mixtures thereof and drawing off the supernatant.
Claim 6
Dependent Claim
32 words
A method according to claim 3 for separating thyroxine from serum or plasma proteins comprising treating the serum or plasma with 1.4 or more volumes of acetonitrile and drawing off the supernatant.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-10-15 | 1983-04-16 | 1983-10-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-10-15 | 1987-04-16 | 1987-10-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-10-15 | 1991-04-16 | 1991-10-16 | $7700.00 | Window Closed / Lapsed |