US4145304A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Resin and method for removing antimicrobials from body fluids
Assignee: Individual
•
Filing: 1977-12-02
•
Granted: 1979-03-20
•
Expires: 1997-12-02
Abstract
Abstract Microporous anionic exchange and non-ionic adsorbent resins which are capable of adsorbing an antibiotic and which have been coated with a non-ionic detergent are disclosed. When contacted with bacterially infected body-fluid specimens, the disclosed resins remove antibiotics from the specimen while exhibiting diminished bacterial adsorption. A combination of a disclosed detergent-coated non-functional adsorbent resin with a cationic resin removes other bacterial inhibitors, as well as antibiotics, from bacterially infected body fluid specimens while permitting the bacteria to remain in the specimens. By removing bacterial inhibitors while sparing the bacteria, the disclosed resins make possible rapid isolation and identification of an infecting organism.
Inventors
- 👤 Joseph L. Melnick
- 👤 Craig Wallis
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 20:29
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/02; B; B01; B01J; B01J20/00; B01J20/22; B01J20/26; B01J20/261; B01J20/262; B01J20/264; B01J20/28; B01J20/28002; B01J20/28004; B01J20/28054; B01J20/28078; B01J20/30; B01J20/3092; B01J20/32; B01J20/3202; B01J20/3206; B01J20/3208; B01J20/321; B01J20/3231; B01J20/3242; B01J20/3268; B01J20/3272; B01J47/00; B01J47/014; B01J47/016; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/521; B01J2220/00; B01J2220/50; B01J2220/58; Y; Y10; Y10S; Y10S424/00; Y10S424/07
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
50 words
A resin for selectively removing an antibiotic from a bacterially infected body fluid specimen, which comprises a microporous resin coated with a non-ionic detergent, which resin is characterized by the ability to adsorb an antibiotic and is selected from the group consisting of anion exchange resins and non-functional adsorbent resins.
Claim 2
Dependent Claim
50 words
A resin for selectively removing an antibiotic from a bacterially infected body fluid specimen, which comprises a microporous resin coated with a non-ionic detergent, which resin is characterized by the ability to adsorb an antibiotic and is selected from the group consisting of anion exchange resins and non-functional adsorbent resins.
Claim 3
Dependent Claim
15 words
The resin of claim 1 wherein the detergent is a polyethylene glycol alkyl aryl ether.
Claim 4
Dependent Claim
13 words
The resin of claim 1 wherein the resin is an anionic exchange resin.
Claim 5
Dependent Claim
13 words
The resin of claim 1 wherein the resin is a non-functional resin adsorbent.
Claim 6
Dependent Claim
21 words
The resin of claim 1 wherein the resin is a non-functional copolymer of styrene and divinyl benzene having a macroreticular structure.
Claim 7
Dependent Claim
12 words
The resin of claim 1 wherein the body fluid specimen is blood.
Claim 8
Dependent Claim
12 words
The resin of claim 1 wherein the body fluid specimen is urine.
Claim 9
Dependent Claim
13 words
The resin of claim 1 wherein the body fluid specimen is spinal fluid.
Claim 10
Dependent Claim
30 words
A resin for selectively removing bacterial inhibitors from body fluid specimens, which comprises a microporous non-functional resin adsorbent, coated with a non-ionic detergent, in combination with a cationic exchange resin.
Claim 11
Dependent Claim
30 words
A resin for selectively removing bacterial inhibitors from body fluid specimens, which comprises a microporous non-functional resin adsorbent, coated with a non-ionic detergent, in combination with a cationic exchange resin.
Claim 12
Dependent Claim
21 words
The resin of claim 9 wherein the resin adsorbent is a copolymer of styrene and divinyl benzene having a macroreticular structure.
Claim 13
Dependent Claim
16 words
The resin of claim 9 wherein the non-ionic detergent is a polyethylene glycol alkyl aryl ether.
References Cited (Backward Citations)
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US3856471A
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US3620681A
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US3625652A
Cited
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-03-19 | 1982-09-18 | 1983-03-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-03-19 | 1986-09-18 | 1987-03-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-03-19 | 1990-09-18 | 1991-03-20 | $7700.00 | Window Closed / Lapsed |