US4143151A
Expired / Lapsed
US
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Method for treating hyperglycemia in mammals using arylamino benzoic acids
Assignee: Dow Chemical Co
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Filing: 1978-07-03
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Granted: 1979-03-06
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Expires: 1998-07-03
Abstract
Abstract A method for treating hyperglycemia in a mammal which comprises administering internally to said mammal a hyperglycemic amount of an arylamino benzoic acid or pharmaceutcially-acceptable salt thereof, wherein aryl represents phenyl, substituted phenyl, thienyl or substituted thienyl.
Inventors
- 👤 Eugene R. Wagner
- 👤 Roger D. McDermott
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 03:41
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/185; A61K31/19; A61K31/195; A61K31/21; A61K31/215; A61K31/235; A61K31/24; A61K31/245; A61K31/33; A61K31/38; A61P; A61P3/00; A61P3/08; A61P3/10
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
82 words
A method for treating hyperglycemia in a mammal which comprises administering internally to said mammal an effective hypoglycemic amount of a compound or pharmaceutically-acceptable salt thereof having the formula ##STR2## wherein R 1 represents hydrogen or a lower alkyl; R 2 represents hydrogen or methyl; n represents an integer of from 0 to 3; and Ar represents phenyl, thienyl, halo substituted thienyl, or substituted phenyl wherein the substituted moieties are selected from the group consisting essentially of halo, lower alkyl, and trihalomethyl.
Claim 2
Independent Claim
82 words
A method for treating hyperglycemia in a mammal which comprises administering internally to said mammal an effective hypoglycemic amount of a compound or pharmaceutically-acceptable salt thereof having the formula ##STR2## wherein R 1 represents hydrogen or a lower alkyl; R 2 represents hydrogen or methyl; n represents an integer of from 0 to 3; and Ar represents phenyl, thienyl, halo substituted thienyl, or substituted phenyl wherein the substituted moieties are selected from the group consisting essentially of halo, lower alkyl, and trihalomethyl.
Claim 3
Dependent Claim
15 words
The method of claim 1 wherein Ar of the compound is phenyl or substituted phenyl.
Claim 4
Dependent Claim
16 words
The method of claim 2 wherein the compound is 4-(((4-chlorophenyl)methyl)amino)benzoic acid or a pharmaceutically-acceptable salt thereof.
Claim 5
Dependent Claim
16 words
The method of claim 1 wherein the compound is 4-(((4-methylphenyl)methyl)amino)benzoic acid or a pharmaceutically-acceptable salt thereof.
Claim 6
Dependent Claim
16 words
The method of claim 2 wherein the compound is 4-(((4-ethylphenyl)methyl)amino)benzoic acid or a pharmaceutically-acceptable salt thereof.
Claim 7
Dependent Claim
16 words
The method of claim 1 wherein Ar of the compound represents thienyl or halo substituted thienyl.
References Cited (Backward Citations)
US3674843A
Cited
US3983164A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-03-05 | 1982-09-04 | 1983-03-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-03-05 | 1986-09-04 | 1987-03-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-03-05 | 1990-09-04 | 1991-03-06 | $7700.00 | Window Closed / Lapsed |