US3674843A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Substituted phenylsulfamyl salicylic acids and derivatives thereof
Assignee: Merck and Co Inc
•
Filing: 1970-04-20
•
Granted: 1972-07-04
•
Expires: 1990-04-20
Abstract
Abstract Substituted phenyl sulfamyl or sulfonamido salicylic acids and non-toxic pharmaceutical accepted salts, esters, amides and various derivatives thereof are claimed. Also a method of treating inflammation which comprises administering various substituted phenyl sulfamyl or sulfonamido salicylic acids and the various derivatives are also claimed. The substituted phenyl sulfamyl or sulfonamido salicylic acids described herein have anti-inflammatory, anti-pyretic and analgesic activity.
Inventors
- 👤 Tsung-Ying Shen
- 👤 Bruce E Witzel
- 👤 Gordon L Walford
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 18:02
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/60
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
25 words
A compound according to claim 1 wherein R1, is hydroxy and R2 and R3 are hydrogen X is fluoro A is NHSO2-thus forming 5-(N-(p-fluorophenylsulfamyl))-salicylic acid.
Claim 2
Dependent Claim
25 words
A compound according to claim 1 wherein R1 is hydroxy and, R2 and R3 are hydrogen X is fluoro A is -SO2-NH-thus forming 5-(fluorophenylsulfonamido)-salicylic acid.
Claim 3
Dependent Claim
25 words
A compound according to claim 1 wherein R1 is hydroxy and, R2 and R3 are hydrogen X is fluoro A is -NHSO2-thus forming 4-(N-(fluorophenylsulfamyl))salicylic acid.
Claim 4
Dependent Claim
25 words
A compound according to claim 1 wherein R1 is hydroxy and, R2 and R3 are hydrogen X is fluoro A is -SO2NH-thus forming 4-(fluorophenylsulfonamido)salicylic acid.
Claim 5
Dependent Claim
27 words
A compound according to claim 1 wherein R1 is hydroxy and, R2 and R3 are hydrogen X is methylsulfonyl A is -SO2NH-thus forming 4 or 5-(methylsulfonylphenylsulfonamido)salicylic acid
Claim 6
Dependent Claim
29 words
A compound according to claim 1 wherein R1 is hydroxy and, R2 and R3 are hydrogen X is methylsulfonyl and A is -NHSO2-thus forming 4 or 5 (N-(methylsulfonylphenylsulfamyl))salicylic acid
Claim 7
Dependent Claim
27 words
A compound according to claim 1 wherein R1 is hydroxy and, R2 and R3 are hydrogen X is methylsulfinyl A is -NHSO2-thus forming 4 or 5-(N-(methylsulfinylphenylsulfamyl))salicylic acid
Claim 8
Dependent Claim
27 words
A compound according to claim 1 wherein R1 is hydroxy and, R2 and R3 are hydrogen X is methylsulfinyl A is -SO2NH-thus forming 4 or 5-(methylsulfinylphenylsulfonamido)salicylic acid.
Claim 9
Dependent Claim
27 words
A compounding according to claim 1 wherein R1 is hydroxy and, R2 and R3 are hydrogen X is trifluoromethyl A is -NHSO2-thus forming 4 or 5-(N-(trifluoromethylphenylsulfamyl))salicylic acid.
Claim 10
Dependent Claim
27 words
A compound according to claim 1 wherein R1 is hydroxy and, R2 and R3 are hydrogen X is trifluoromethyl A is -SO2NH-thus forming 4 or 5-(trifluoromethylphenylsulfonamido)salicylic acid.
Claim 11
Dependent Claim
27 words
A compound according to claim 1 wherein R1 is hydroxy and, R2 and R3 are hydrogen X is dimethylamino A is -NHSO2-thus forming 4 or 5-(N-(dimethylaminophenylsulfamyl))salicylic acid.
Claim 12
Dependent Claim
27 words
A compound according to claim 1 wherein R1 is hydroxy and, R2 and R3 are hydrogen X is dimethylamino A is -SO2NH-thus forming 4 or 5-(dimethylaminophenylsulfonamido)salicylic acid.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-07-04 | 1976-01-03 | 1976-07-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-07-04 | 1980-01-03 | 1980-07-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-07-04 | 1984-01-03 | 1984-07-04 | $7700.00 | Window Closed / Lapsed |