Patent US4136177A successfully refreshed from Google Patents.
US4136177A
Expired / Lapsed
US
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Xanthan gum therapeutic compositions
Assignee: Wyeth LLC
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Filing: 1977-01-31
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Granted: 1979-01-23
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Expires: 1997-01-31
Abstract
Abstract Ophthalmic compositions are disclosed comprising an ophthalmic drug and xanthan gum.
Inventors
- 👤 Song-Ling Lin
- 👤 Maturu K. Pramoda
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 16:54
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0048; A61K31/00; A61K31/70; A61K31/715
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
39 words
A composition consisting essentially of a therapeutically effective amount of a topically effective ophthalmic drug and about 0.01% to about 2.5% of xanthan gum in a pharmaceutically acceptable liquid vehicle, said liquid vehicle comprising about 50-100% water by volume.
Claim 2
Dependent Claim
39 words
A composition consisting essentially of a therapeutically effective amount of a topically effective ophthalmic drug and about 0.01% to about 2.5% of xanthan gum in a pharmaceutically acceptable liquid vehicle, said liquid vehicle comprising about 50-100% water by volume.
Claim 3
Dependent Claim
26 words
The composition of claim 1 wherein the concentration of said xanthan gum is from about 0.02% to about 1.0% said percentages expressed as weight per volume.
Claim 4
Dependent Claim
12 words
The composition of claim 1 wherein said ophthalmic drug is echothiophate iodide.
Claim 5
Dependent Claim
12 words
The composition of claim 1 wherein said ophthalmic drug is pilocarpine hydrochloride.
Claim 6
Dependent Claim
11 words
The composition of claim 1 wherein said ophthalmic drug is carbachol.
Claim 7
Dependent Claim
51 words
An ophthalmic composition effective in the treatment of glaucoma consisting essentially of about 0.005% to about 0.25% echothiophate iodide and about 0.02% to about 1% of xanthan gum in a pharmaceutically acceptable liquid vehicle; said percentages expressed as weight per volume, and said liquid vehicle comprising about 50-100% water by volume.
Claim 8
Dependent Claim
51 words
An ophthalmic composition effective in the treatment of glaucoma consisting essentially of about 0.005% to about 0.25% echothiophate iodide and about 0.02% to about 1% of xanthan gum in a pharmaceutically acceptable liquid vehicle; said percentages expressed as weight per volume, and said liquid vehicle comprising about 50-100% water by volume.
Claim 9
Dependent Claim
34 words
The ophthalmic composition of claim 6 wherein the concentration of said echothiophate iodide is about 0.03% to about 0.25% and wherein the concentration of said xanthan gum is from about 0.1% to about 0.5%.
Claim 10
Dependent Claim
45 words
An ophthalmic composition consisting essentially of about 0.01% to about 0.05% of pilocarpine hydrochloride and about 0.02% to about 1.0% of xanthan gum in a pharmaceutically acceptable liquid vehicle; said percentages expressed as weight per volume, said liquid vehicle comprising about 50-100% water by volume.
Claim 11
Dependent Claim
45 words
An ophthalmic composition consisting essentially of about 0.01% to about 0.05% of pilocarpine hydrochloride and about 0.02% to about 1.0% of xanthan gum in a pharmaceutically acceptable liquid vehicle; said percentages expressed as weight per volume, said liquid vehicle comprising about 50-100% water by volume.
Claim 12
Dependent Claim
48 words
An ophthalmic composition consisting essentially a therapeutically effective amount of 1,3-dioxo-1 H-benz isoquinoline-2(3H)-acetic acid and about 0.5% to about 1.5% of xanthan gum in a pharmaceutically acceptable liquid vehicle and wherein said percentages are expressed as weight per volume, said liquid vehicle comprising about 50-100% water by volume.
Claim 13
Dependent Claim
48 words
An ophthalmic composition consisting essentially a therapeutically effective amount of 1,3-dioxo-1 H-benz isoquinoline-2(3H)-acetic acid and about 0.5% to about 1.5% of xanthan gum in a pharmaceutically acceptable liquid vehicle and wherein said percentages are expressed as weight per volume, said liquid vehicle comprising about 50-100% water by volume.
Claim 14
Independent Claim
48 words
A method for the treatment of the eye of a mammalian patient by potentiating the pharmacological response of topically effective drugs which consists essentially of applying to said eye a liquid composition containing a therapeutically effective amount of said drug and about 0.01% to about 2.5% xanthan gum.
Claim 15
Independent Claim
48 words
A method for the treatment of the eye of a mammalian patient by potentiating the pharmacological response of topically effective drugs which consists essentially of applying to said eye a liquid composition containing a therapeutically effective amount of said drug and about 0.01% to about 2.5% xanthan gum.
Claim 16
Dependent Claim
47 words
An ophthalmic gel composition for topical application consisting essentially of about 1.0% to about 2.5% of xanthan gum and a topically effective ophthalmic drug in a pharmaceutically acceptable liquid vehicle; said percentages expressed as weight per volume, and said liquid vehicle comprising about 50-100% water by volume.
Claim 17
Dependent Claim
47 words
An ophthalmic gel composition for topical application consisting essentially of about 1.0% to about 2.5% of xanthan gum and a topically effective ophthalmic drug in a pharmaceutically acceptable liquid vehicle; said percentages expressed as weight per volume, and said liquid vehicle comprising about 50-100% water by volume.
Claim 18
Dependent Claim
36 words
An ophthalmic composition consisting essentially of about 0.02% to about 1.0% of xanthan gum and a therapeutically effective amount of carbachol in a pharmaceutically acceptable liquid vehicle, said liquid vehicle comprising about 50-100% water by volume.
Claim 19
Dependent Claim
36 words
An ophthalmic composition consisting essentially of about 0.02% to about 1.0% of xanthan gum and a therapeutically effective amount of carbachol in a pharmaceutically acceptable liquid vehicle, said liquid vehicle comprising about 50-100% water by volume.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-01-22 | 1982-07-24 | 1983-01-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-01-22 | 1986-07-24 | 1987-01-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-01-22 | 1990-07-24 | 1991-01-23 | $7700.00 | Window Closed / Lapsed |