Patent US1085338A successfully refreshed from Google Patents.
Patent US4091032A successfully refreshed from Google Patents.
US4091032A
Expired / Lapsed
US
⏱️ 0.0 years remaining
4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A
Assignee: Abbott Laboratories
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Filing: 1976-09-23
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Granted: 1978-05-23
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Expires: 1996-09-23
Abstract
Abstract This invention provides 4-N-acylfortimicin B derivatives of the structure ##STR1## wherein R is acyl, aminoacyl, N-monoloweralkylaminoacyl, N,N-diloweralkylaminoacyl, hydroxy-substituted aminoacyl, or substituted aminoacyl of the formula ##STR2## where R 1 is an acyl radical derived from an amino acid or a short peptide, and the pharmaceutically acceptable salts thereof. The compounds are useful as intermediates for preparing 4-N-alkyl or substituted alkylfortimicin B derivatives. In addition to their utility as intermediates, some of the compounds of this invention are also useful as antimicrobial agents.
Inventors
- 👤 John Soloman Tadanier
- 👤 Jerry Roy Martin
- 👤 Paul Kurath
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 15:05
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/20; C07H15/22; C07H15/222; C07H15/224; A; A61; A61P; A61P31/00; A61P31/04
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
2 words
1,2',6'-Tri-N-benzyloxycarbonylfortimicin A.
Claim 2
Dependent Claim
2 words
1,2',6'-Tri-N-benzyloxycarbonylfortimicin A.
Claim 3
Dependent Claim
4 words
1,2', 6'-Tri-N-benzyloxycarbonylfortimicin A trifluoroacetate.
Claim 4
Dependent Claim
4 words
1,2', 6'-Tri-N-benzyloxycarbonylfortimicin A trifluoroacetate.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-05-22 | 1981-11-21 | 1982-05-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-05-22 | 1985-11-21 | 1986-05-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-05-22 | 1989-11-21 | 1990-05-23 | $7700.00 | Window Closed / Lapsed |