US3931400A
Expired / Lapsed
US
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Fortimicin B and process for production thereof
Assignee: Abbott Laboratories
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Filing: 1974-04-05
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Granted: 1976-01-06
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Expires: 1994-04-05
Abstract
Abstract A new antibiotic, Fortimicin B, is produced by fermentation of a microorganism belonging to the genus Micromonospora. The antibiotic is accumulated in the culture medium and is isolated therefrom.
Inventors
- 👤 Takashi Nara
- 👤 Seigo Takasawa
- 👤 Ryo Okachi
- 👤 Isao Kawamoto
- 👤 Mitsuyoshi Yamamoto
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 06:12
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/20; C07H15/22; C07H15/222; C07H15/224; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/822; Y10S435/863
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
69 words
A composition of matter having antibiotic activity characterized by: a. molecular weight of 348; b. molecular formula of C 15 H 32 N 4 O 5 ; c. an ultraviolet absorption spectrum essentially as shown in FIG. 1; d. an infrared absorption spectrum essentially as shown in FIG. 2; and e. a nuclear magnetic reasonance spectrum essentially as shown in FIG. 3. said composition of matter being Fortimicin B.
Claim 2
Dependent Claim
69 words
A composition of matter having antibiotic activity characterized by: a. molecular weight of 348; b. molecular formula of C 15 H 32 N 4 O 5 ; c. an ultraviolet absorption spectrum essentially as shown in FIG. 1; d. an infrared absorption spectrum essentially as shown in FIG. 2; and e. a nuclear magnetic reasonance spectrum essentially as shown in FIG. 3. said composition of matter being Fortimicin B.
Claim 3
Dependent Claim
45 words
A pharmaceutically acceptable, non-toxic acid addition salt of the composition of matter of claim 1, said acid addition salt being selected from the group consisting of the hydrochloride, hydrobromide, hydroiodide, sulfate, sulfamate, phosphate, maleate, acetate, citrate, oxalate, succinate, benzoate, tartrate, fumarate, malate, mandelate and ascorbate.
Claim 4
Dependent Claim
67 words
A process for producing the antibiotic Fortimicin B which comprises culturing a microorganism selected from the group consisting of Micromonospora olivoasterospora ATCC 21819, Micromonospora olivoasterospora ATCC 31009 and Micromonospora olivoasterospora ATCC 31010 in a nutrient medium containing assimilable sources of carbon and nitrogen at 25° to 40°C. and at about neutral pH until substantial antibacterial activity is detected in the culture liquor and thereafter isolating Fortimicin B.
Claim 5
Dependent Claim
67 words
A process for producing the antibiotic Fortimicin B which comprises culturing a microorganism selected from the group consisting of Micromonospora olivoasterospora ATCC 21819, Micromonospora olivoasterospora ATCC 31009 and Micromonospora olivoasterospora ATCC 31010 in a nutrient medium containing assimilable sources of carbon and nitrogen at 25° to 40°C. and at about neutral pH until substantial antibacterial activity is detected in the culture liquor and thereafter isolating Fortimicin B.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-01-05 | 1979-07-07 | 1980-01-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-01-05 | 1983-07-07 | 1984-01-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-01-05 | 1987-07-07 | 1988-01-06 | $7700.00 | Window Closed / Lapsed |