US4088752A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Oral composition for plaque and caries inhibition
Assignee: Gaba Schweiz AG
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Filing: 1975-06-02
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Granted: 1978-05-09
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Expires: 1995-06-02
Abstract
Abstract Oral compositions for plaque and caries inhibition contain a salt of an oxo-acid (formerly called oxy-acid) of phosphorus or a mixed salt of an oxo-acid of phosphorus and hydrofluoric acid with an organic base.
Inventors
- 👤 Hans R. Muhlemann
- 👤 Hans Schmid
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 09:26
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/55; A61K8/40; A61K8/41; A61K8/416; A61Q; A61Q11/00
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
301 words
An oral fluoride-free dentifrice composition selected from the group consisting of toothpastes, transparent toothpastes, gels, mouth rinses, sprays, and chewing gum, for plaque and caries inhibition, said composition containing a salt formed by reaction of an oxo-acid of phosphorus with an organic amine base, said organic amine base being of the formula R-X, where R is selected from the group consisting of an alkyl group having 6 to 30 carbon atoms, an alkenyl group having 6 to 30 carbon atoms, an alkoxy group having 2 to 30 carbon atoms, an alkylol group having 2 to 30 carbon atoms, a substituted or unsubstituted, saturated or unsaturated aralkyl group substituted with an alkyl group having a chain length of 2 to 30 carbon atoms, and X is selected from the group consisting of: (a) (NH 2 ) y where y is an integer from 1 to 3, (b) the grouping ##STR6## where R 1 and R 2 , which can be the same or different, are selected from the group consisting of hydrogen, acyl, alkyl, alkoxy, alkenyl, alkylol, aralkyl and cycloalkyl groups, (c) the grouping ##STR7## where R 3 , R 4 and R 5 , which can be the same or different, are selected from the group consisting of hydrogen, acyl, alkyl, alkoxy, alkenyl, alkylol, aralkyl and cycloalkyl groups, and x is an integer from 1 to 3, (d) the grouping ##STR8## where R 6 is selected from the group consisting of hydrogen, acyl, alkyl, alkoxy, alkenyl, alkylol, aralkyl and cycloalkyl groups, (e) the grouping ##STR9## where R 7 is selected from the group consisting of hydrogen and lower alkyl groups, and (f) the grouping ##STR10## where R 8 and R 9 , which can be the same or different, are selected from the group consisting of hydrogen and lower alkyl groups.
Claim 2
Dependent Claim
301 words
An oral fluoride-free dentifrice composition selected from the group consisting of toothpastes, transparent toothpastes, gels, mouth rinses, sprays, and chewing gum, for plaque and caries inhibition, said composition containing a salt formed by reaction of an oxo-acid of phosphorus with an organic amine base, said organic amine base being of the formula R-X, where R is selected from the group consisting of an alkyl group having 6 to 30 carbon atoms, an alkenyl group having 6 to 30 carbon atoms, an alkoxy group having 2 to 30 carbon atoms, an alkylol group having 2 to 30 carbon atoms, a substituted or unsubstituted, saturated or unsaturated aralkyl group substituted with an alkyl group having a chain length of 2 to 30 carbon atoms, and X is selected from the group consisting of: (a) (NH 2 ) y where y is an integer from 1 to 3, (b) the grouping ##STR6## where R 1 and R 2 , which can be the same or different, are selected from the group consisting of hydrogen, acyl, alkyl, alkoxy, alkenyl, alkylol, aralkyl and cycloalkyl groups, (c) the grouping ##STR7## where R 3 , R 4 and R 5 , which can be the same or different, are selected from the group consisting of hydrogen, acyl, alkyl, alkoxy, alkenyl, alkylol, aralkyl and cycloalkyl groups, and x is an integer from 1 to 3, (d) the grouping ##STR8## where R 6 is selected from the group consisting of hydrogen, acyl, alkyl, alkoxy, alkenyl, alkylol, aralkyl and cycloalkyl groups, (e) the grouping ##STR9## where R 7 is selected from the group consisting of hydrogen and lower alkyl groups, and (f) the grouping ##STR10## where R 8 and R 9 , which can be the same or different, are selected from the group consisting of hydrogen and lower alkyl groups.
Claim 3
Dependent Claim
13 words
A composition according to claim 1 wherein the oral composition is a toothpaste.
Claim 4
Dependent Claim
14 words
A composition according to claim 1 wherein the oral composition is a mouth rinse.
Claim 5
Dependent Claim
25 words
A composition according to claim 1 wherein the oxo-acid of phosphorus is selected from the group consisting of orthophosphoric acids, pyrophosphoric acids and metaphosphoric acids.
Claim 6
Dependent Claim
40 words
A composition according to claim 1 wherein x has the formula: ##STR11## where a, b and c are the same or different numbers with a mean value such that the sum a + b + c = 3 to 36.
Claim 7
Dependent Claim
34 words
A composition according to claim 1 wherein R is selected from the group consisting of alkyl groups of 14 to 18 carbon atoms and mixtures of alkyl groups having 14 to 18 carbon atoms.
Claim 8
Dependent Claim
16 words
A composition according to claim 4 wherein the oxo-acid of phosphorus is a cyclic metaphosphoric acid.
Claim 9
Dependent Claim
12 words
A composition according to claim 6 wherein R is a tallow-alkyl group.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-05-08 | 1981-11-07 | 1982-05-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-05-08 | 1985-11-07 | 1986-05-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-05-08 | 1989-11-07 | 1990-05-09 | $7700.00 | Window Closed / Lapsed |