Patent US4066894A successfully refreshed from Google Patents.
US4066894A
Expired / Lapsed
US
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Positive and negative ion recording system for mass spectrometer
Assignee: University of Virginia
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Filing: 1976-01-20
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Granted: 1978-01-03
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Expires: 1996-01-20
Abstract
Abstract A method and an apparatus are disclosed for adapting a conventional quadrupole mass spectrometer to substantially simultaneously produce and record both positive and negative ions. The apparatus includes a control circuit for rapidly switching the repeller, source and lens electrodes of a quadrupole mass spectrometer between positive and negative potentials. This switching of the potentials, along with the selection of appropriately favorable ionization conditions, permits the generation of suitable streams of positive and negative ions. A dual electron multiplier detector is used for separately sensing the positive and negative ions transmitted through the quadrupole mass spectrometer. The disclosed method and apparatus are particularly suitable for obtaining accurate mass measurements using a quadrupole mass spectrometer.
Inventors
- 👤 Donald F. Hunt
- 👤 George C. Stafford, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 22:30
CPC Classifications
H; H01; H01J; H01J49/00; H01J49/26; H01J49/34; H01J49/42; H01J49/4205; H01J49/421; H01J49/4215; H01J49/0095; H01J49/02; H01J49/025
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
88 words
A method of generating and monitoring positive and negative ions substantially simultaneously using a quadrupole mass spectrometer having an ion generator with repeller, source and lens electrodes, and a quadrupole filter, comprising the steps of: operating the mass spectrometer under conditions favoring the generation of positive and negative ions; alternately transmitting the positive ions and the negative ions at a frequency in excess of 1 kHz, through the quadrupole filter; and separately extracting the alternately transmitted positive ions and negative ions at the output of the quadrupole filter.
Claim 2
Independent Claim
88 words
A method of generating and monitoring positive and negative ions substantially simultaneously using a quadrupole mass spectrometer having an ion generator with repeller, source and lens electrodes, and a quadrupole filter, comprising the steps of: operating the mass spectrometer under conditions favoring the generation of positive and negative ions; alternately transmitting the positive ions and the negative ions at a frequency in excess of 1 kHz, through the quadrupole filter; and separately extracting the alternately transmitted positive ions and negative ions at the output of the quadrupole filter.
Claim 3
Dependent Claim
33 words
The method recited in claim 1 including the steps of: producing electrical signals representative of the positive ions and the negative ions extracted in the step of extracting; and processing the electrical signals.
Claim 4
Dependent Claim
41 words
The method recited in claim 1, wherein the step of operating includes the steps of: using a reagent gas such as isobutane at a pressure of approximately one torr as a reagent gas; and using perfluorokerosene as an internal standard material.
Claim 5
Dependent Claim
26 words
The method recited in claim 1 wherein the step of transmitting includes the step of: switching the relative potential applied between source and quadrupole filter electrodes.
Claim 6
Dependent Claim
30 words
The method recited in claim 1 wherein the transmitting step includes: alternately transmitting the positive ions and the negative ions at a frequency of 10 kHz. through the quadrupole filter.
Claim 7
Independent Claim
77 words
An apparatus for enabling a quadrupole mass spectrometer, having an ion generator with repeller, source and lens electrodes, and a quadrupole filter, to effectively simultaneously generate and monitor both positive and negative ions, comprising: means for alternately transmitting positive ions and negative ions at a frequency in excess of 1 kHz. through the quadrupole filter; and dual extraction means for separately extracting the alternately transmitted positive ions and negative ions at the output of the quadrupole filter.
Claim 8
Independent Claim
77 words
An apparatus for enabling a quadrupole mass spectrometer, having an ion generator with repeller, source and lens electrodes, and a quadrupole filter, to effectively simultaneously generate and monitor both positive and negative ions, comprising: means for alternately transmitting positive ions and negative ions at a frequency in excess of 1 kHz. through the quadrupole filter; and dual extraction means for separately extracting the alternately transmitted positive ions and negative ions at the output of the quadrupole filter.
Claim 9
Dependent Claim
55 words
The apparatus recited in claim 6 wherein the transmitting means includes: a plurality of independently adjustable voltage sources; electronic switching circuit means coupled to the voltage sources for selectively connecting the voltage sources with said quadrupole mass spectrometer; and timing circuit means coupled to the electronic switching circuit means for controlling the switching frequency thereof.
Claim 10
Dependent Claim
43 words
The apparatus recited in claim 7 wherein the transmitting means includes: mode selective switch means coupled to the timing and electronic switching circuit means for selectively disabling the timing circuit means and for selectively establishing a fixed condition of the switching circuit means.
Claim 11
Dependent Claim
29 words
The apparatus recited in claim 7 wherein: the plurality of voltage sources includes at least four independently variable voltage dividers for independently setting desired positive and negative voltage levels.
Claim 12
Dependent Claim
30 words
The apparatus recited in claim 8 wherein the transmitting means includes: output power amplifiers adapted to be coupled between the switching circuit means and the repeller, source and lens electrodes.
Claim 13
Dependent Claim
55 words
The apparatus recited in claim 6 wherein the dual extraction means includes: a pair of electron multiplier tubes adapted to be coupled to the output of the quadrupole filter; negative biasing means coupled to one of the tubes for attracting positive ions; and positive biasing means coupled to the other tube for attracting negative ions.
Claim 14
Dependent Claim
24 words
The apparatus recited in claim 11 including: cross-talk reducing means coupled to the dual extraction means for reducing cross-talk between the electron multiplier tubes.
Claim 15
Dependent Claim
51 words
The apparatus recited in claim 12 wherein the cross-talk reducing means includes: a conductive plate including a pair of apertures, the apertures positioned to permit ions to pass through the plate and impinge upon the electron multiplier tubes; and an upstanding separating fin secured to the plate midway between the apertures.
References Cited (Backward Citations)
US2939952A
Cited
US2816243A
Cited
US3193722A
Cited
US3280326A
Cited
US3555272A
Cited
US3849656A
Cited
US3641340A
Cited
US3629573A
Cited
US3767914A
Cited
US3925662A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-01-02 | 1981-07-04 | 1982-01-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-01-02 | 1985-07-04 | 1986-01-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-01-02 | 1989-07-04 | 1990-01-03 | $7700.00 | Window Closed / Lapsed |