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US4062934A
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US
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X-ray contrast media
Assignee: Laboratoires Andre Guerbet
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Filing: 1976-05-25
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Granted: 1977-12-13
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Expires: 1996-05-25
Abstract
Abstract This invention relates to compounds having the following general formula: ##STR1## in which n is an integer from 0 to 4; R 1 and R 2 represent independently from each other a radical of the formula --CONHR 5 in which R 5 is an alkyl radical having 1-4 carbon atoms or a hydroxyalkyl radical having 1-4 carbon atoms or a radical of the formula ##STR2## in which R 6 and R 7 are alkyl radicals having 1-4 carbon atoms; and R 3 and R 4 , independently from each other, represent a hydrogen atom or an alkyl radical having 1-4 carbon atoms. Said compounds are useful as X-ray contrast media, particularly for myelography.
Inventors
- 👤 Guy Tilly
- 👤 Michel Jean-Charles Hardouin
- 👤 Jean Lautrou
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 22:36
CPC Classifications
C; C07; C07C; C07C243/00; C07C243/24; C07C243/38
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
110 words
Compounds having the general formula: ##STR37## in which: n is an integer from 0 to 4, R 1 and R 2 , independently from each other, are selected from the group consisting of a radical of the formula --CONHR 5 , in which R 5 is selected from the group consisting of alkyl having 1-4 carbon atoms and hydroxyalkyl having 1-4 carbon atoms, and a radical of the formula ##STR38## in which R 6 and R 7 each represent alkyl radicals having 1-4 carbon atoms, and R 3 and R 4 , independently from each other, are selected from the group consisting of hydrogen and alkyl having 1-4 carbon atoms.
Claim 2
Dependent Claim
110 words
Compounds having the general formula: ##STR37## in which: n is an integer from 0 to 4, R 1 and R 2 , independently from each other, are selected from the group consisting of a radical of the formula --CONHR 5 , in which R 5 is selected from the group consisting of alkyl having 1-4 carbon atoms and hydroxyalkyl having 1-4 carbon atoms, and a radical of the formula ##STR38## in which R 6 and R 7 each represent alkyl radicals having 1-4 carbon atoms, and R 3 and R 4 , independently from each other, are selected from the group consisting of hydrogen and alkyl having 1-4 carbon atoms.
Claim 3
Dependent Claim
1 words
1,2-N,N'-bis(2,4,6-triiodo-3-N-methyl-N-acetylamino-5-N-gluconylamino-benzoyl)diamino-ethane.
Claim 4
Dependent Claim
1 words
1,2-N,N'-bis(2,4,6-triiodo-3-N-methyl-N-acetylamino-5-N-gluconylamino-benzoyl)diamino-ethane.
Claim 5
Dependent Claim
28 words
X-ray contrast medium consisting of an aqueous solution containing 5-100 g of a compound of the formula (I) as claimed in claim 1 per 100 ml of solution.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-12-12 | 1981-06-13 | 1981-12-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-12-12 | 1985-06-13 | 1985-12-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-12-12 | 1989-06-13 | 1989-12-13 | $7700.00 | Window Closed / Lapsed |