Patent US4028405A successfully refreshed from Google Patents.
US4028405A
Expired / Lapsed
US
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Fluorinated amino acids
Assignee: Merck and Co Inc
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Filing: 1976-06-07
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Granted: 1977-06-07
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Expires: 1996-06-07
Abstract
Abstract Deutero analogs of 3-fluoro-D-alanine prepared by direct photofluorination of the D-amino acids demonstrate in vivo and in vitro antibacterial activity against both gram negative and gram positive microorganisms. Deuters analogs of 3-fluoro-L-alanine and 3-fluoro-D,L-alanine also demonstrate useful in vitro activity.
Inventors
- 👤 Janos Kollonitsch
- 👤 Frederick M. Kahan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 13:26
CPC Classifications
C; C07; C07C; C07C227/00; C07C227/04; C07C227/06; C07C227/08
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
16 words
A compound of structural formula ##STR2## wherein X is 1 or 2 and y is 2.
Claim 2
Dependent Claim
16 words
A compound of structural formula ##STR2## wherein X is 1 or 2 and y is 2.
Claim 3
Dependent Claim
1 words
2-Deutero-3-fluoro-D-alanine.
Claim 4
Dependent Claim
1 words
2-Deutero-3-fluoro-D-alanine.
Claim 5
Dependent Claim
1 words
2,3,3-Trideutero-3-fluoro-D-alanine.
Claim 6
Dependent Claim
1 words
2,3,3-Trideutero-3-fluoro-D-alanine.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-06-06 | 1980-12-06 | 1981-06-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-06-06 | 1984-12-06 | 1985-06-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-06-06 | 1988-12-06 | 1989-06-07 | $7700.00 | Window Closed / Lapsed |