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US4021574A
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Antidandruff compositions containing 9-(4-lower alkoxy-2,3,6-trilower-alkylphenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid lower alkyl amides
Assignee: Hoffmann La Roche Inc
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Filing: 1975-09-09
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Granted: 1977-05-03
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Expires: 1995-09-09
Abstract
Abstract Compositions suitable for the care of the hair and scalp particularly with respect to the control of dandruff are disclosed. Said compositions comprise a suitable inert carrier and, as an active ingredient, a compound selected from those represented by the formula <IMAGE> I wherein R1, R2, R3, R4 and R6 are lower alkyl.
Inventors
- 👤 Werner Bollag
- 👤 Rudolf Ruegg
- 👤 Gottlieb Ryser
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 14:21
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/42; A61Q; A61Q5/00; A61Q5/006; A61Q5/02; C; C07; C07C; C07C43/00; C07C43/02; C07C43/20; C07C43/205; C07C45/00; C07C45/61; C07C45/67; C07C45/68; C07C45/72; C07C45/74; C07C59/00; C07C59/40; C07C59/58; C07C59/64; Y; Y10; Y10S; Y10S424/00; Y10S424/02; Y10S424/04
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
63 words
A composition for application to the hair and scalp for the treatment of dandruff comprising a pharmaceutically acceptable hair lotion or dressing containing, as an active ingredient, from about 0.005% by weight to about 0.2% by weight of a compound represented by the formula ##STR6## wherein R 1 , R 2 , R 3 , R 4 and R 6 are lower alkyl.
Claim 2
Dependent Claim
63 words
A composition for application to the hair and scalp for the treatment of dandruff comprising a pharmaceutically acceptable hair lotion or dressing containing, as an active ingredient, from about 0.005% by weight to about 0.2% by weight of a compound represented by the formula ##STR6## wherein R 1 , R 2 , R 3 , R 4 and R 6 are lower alkyl.
Claim 3
Dependent Claim
24 words
The composition in accordance with claim 1 wherein said active ingredient is present in from about 0.01% by weight to about 0.1% by weight.
Claim 4
Dependent Claim
24 words
The composition in accordance with claim 1 wherein said active ingredient is present in from about 0.05% by weight to about 0.06% by weight.
Claim 5
Dependent Claim
16 words
The composition in accordance with claim 1 wherein said active ingredient is 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-nona-2,4,6,8-tetraen-1-oic acid ethyl amide.
Claim 6
Dependent Claim
28 words
A method for the treatment of dandruff which comprises applying to the scalp of an individual requiring such treatment an effective amount of the composition of claim 1.
Claim 7
Dependent Claim
33 words
The method in accordance with claim 5 wherein a sufficient amount of said composition is applied to the scalp to provide from about 0.25 mg to about 20 mg of said active ingredient.
Claim 8
Dependent Claim
60 words
A composition for application to the hair and scalp for the treatment of dandruff comprising a pharmaceutically acceptable shampoo containing, as an active ingredient, from about 0.05% by weight to about 2.0% by weight of a compound represented by the formula ##STR7## wherein R 1 , R 2 , R 3 , R 4 and R 6 are lower alkyl.
Claim 9
Dependent Claim
60 words
A composition for application to the hair and scalp for the treatment of dandruff comprising a pharmaceutically acceptable shampoo containing, as an active ingredient, from about 0.05% by weight to about 2.0% by weight of a compound represented by the formula ##STR7## wherein R 1 , R 2 , R 3 , R 4 and R 6 are lower alkyl.
Claim 10
Dependent Claim
24 words
The composition in accordance with claim 7 wherein said active ingredient is present in from about 0.1% by weight to about 1.0% by weight.
Claim 11
Dependent Claim
24 words
The composition in accordance with claim 7 wherein said active ingredient is present in from about 0.5% by weight to about 0.6% by weight.
Claim 12
Dependent Claim
16 words
The composition in accordance with claim 7 wherein said active ingredient is 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-nona-2,4,6,8-tetraen-1-oic acid ethyl amide.
Claim 13
Dependent Claim
28 words
A method for the treatment of dandruff which comprises applying to the scalp of an individual requiring such treatment an effective amount of the composition of claim 7.
Claim 14
Dependent Claim
33 words
The method in accordance with claim 11 wherein a sufficient amount of said composition is applied to the scalp to provide from about 2.5 mg to about 200 mg of said active ingredient.
References Cited (Backward Citations)
US2677697A
Cited
US3780102A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-05-02 | 1980-11-01 | 1981-05-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-05-02 | 1984-11-01 | 1985-05-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-05-02 | 1988-11-01 | 1989-05-03 | $7700.00 | Window Closed / Lapsed |