Substituted cinnamamides

Abstract

Abstract C2H5NH-COO-C2H4- THE PRESENT INVENTION CONCERNS NEW CINNAMAMIDES OF FORMULA: (R1,R2,R3-PHENYL)-C(-R4)=C(-R5)-CO-N(-R6)-C(-R7)(-R8)- CH(-R9)-R10 IN WHICH R1 AND R3 ARE HYDROGEN, A LOWER ALKYL OR LOWER ALKOXY RADICAL; R2 IS HYDROGEN, A HALOGEN, A LOWER ALKYL OR LOWER ALKOXY RADICAL; R4 AND R5 ARE HYDROGEN OR A LOWER ALKYL RADICAL; R6 IS HYDROGEN, A LOWER ALKYL OR LOWER HYDROXYL ALKYL RADICAL ARYL RADICAL OR R7 AND R8 ARE HYDROGEN, A LOW ALKYL OR LOWER HYDROXY, ALKYL RADICAL; R9 IS HYDROGEN, A LOWER ALKYL OR LOWER HYDROXY ALKYL RADICAL; R10=HALOGEN, A HYDROXY RADICAL EXCEPT WHEN R1 TO R9=H AND R1, R2, R3=CH3O, R4=CH3 AND R5 TO R9=H, A LOWER ALKYL RADICAL, A LOWER HYDROXYALKYL RADICAL, NH2-COO, A LOWER ALKYL RADICAL -NH-COO AND ARYL RADICAL-NH-COO. THE INVENTION IS RELATIVE TO PREPARATION PROCESSES AND MEDICINE CONTAINING AS ACTIVE PRINCIPLE A CINNAMAMIDE OF FORMULA I, IN WHICH THE RADICALS R1 TO R9 HAVE THE SAME MEANINGS A S ABOVE AND R10=HALOGEN, A HYDROXY RADICAL-EXCEPT WHEN R1, R2, R3=CH3O, R4=CH3 AND R5 TO R9=H-LOWER HYDROXY ALKYL, NH2COO, LOWER ALKYL-NHCOO-ARYL NHCOO.

Inventors

• 👤 M Grand
• 👤 M Bayssat
• 👤 L Fontaine

Bibliographic Details