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US3979261A
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Production of glucose isomerase by bacillus coagulans
Assignee: Novo Nordisk AS
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Filing: 1973-12-27
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Granted: 1976-09-07
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Expires: 1993-12-27
Abstract
Abstract A superior glucose isomerase is present intracellularly in an atypical B. coagulans characterized by an ability to grow on inorganic sources of nitrogen.
Inventors
- 👤 Helle Outtrup
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 09:42
CPC Classifications
C; C12; C12N; C12N9/00; C12N9/90; C12N9/92; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/822; Y10S435/832
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
86 words
A process for the production of glucose isomerase, comprising cultivating under aerobic conditions an atypical Bacillus coagulans productive of a glucose isomerase, said Bacillus coagulans being capable of growth on only inorganic nitrogen sources as the nitrogen source and at a temperature of 65°C on a nutrient medium containing a nitrogen source, a carbon source, optionally including xylose, small amounts of inorganic salts, at a pH value between 5 and 9 and a temperature between 40° and 65°C, whereafter the glucose isomerase thus produced is recovered.
Claim 2
Dependent Claim
86 words
A process for the production of glucose isomerase, comprising cultivating under aerobic conditions an atypical Bacillus coagulans productive of a glucose isomerase, said Bacillus coagulans being capable of growth on only inorganic nitrogen sources as the nitrogen source and at a temperature of 65°C on a nutrient medium containing a nitrogen source, a carbon source, optionally including xylose, small amounts of inorganic salts, at a pH value between 5 and 9 and a temperature between 40° and 65°C, whereafter the glucose isomerase thus produced is recovered.
Claim 3
Dependent Claim
24 words
A process as claimed in claim 1 in which a mutant atypical Bacillus coagulans strain is cultivated in a growth medium free of xylose.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-09-07 | 1980-03-08 | 1980-09-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-09-07 | 1984-03-08 | 1984-09-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-09-07 | 1988-03-08 | 1988-09-07 | $7700.00 | Window Closed / Lapsed |