Patent US3939276A successfully refreshed from Google Patents.
US3939276A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Cyclic carbonyl compounds
Assignee: SmithKline Beecham Corp
•
Filing: 1973-03-06
•
Granted: 1976-02-17
•
Expires: 1993-03-06
Abstract
Abstract Certain fluorenone and anthraquinone compounds, each of which is 2-substituted by a carboxyl group or a salt, ester or optionally substituted amide thereof and each of which is optionally substituted in the 5,6-,7- or 8- position, by a second carboxyl group, salt, ester or optionally substituted amide thereof, the substitutent in the 5,6-7- or 8- position of the fluorenone compounds, also being selected from cyano, halogen, nitro, alkyl, alkoxy and acyl, are useful for the relief or prophylaxis of allergic conditions.
Inventors
- 👤 Harold Francis Hodson
- 👤 John Frederick Batchelor
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 12:20
CPC Classifications
C; C07; C07C; C07C66/00; C07C66/02; C07C51/00; C07C51/41; C07C51/412; C07C65/00; C07C65/32; C07C65/34; C07C65/36; C07C65/40
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
83 words
A method of preventing the symptoms of asthma or allergic rhinitis in a mammal having asthma or allergic rhinitis which comprises administering to said mammal a prophylactically effective amount of a compound of formula ##SPC14## where Z 1 is selected from the group consisting of carboxyl, a pharmaceutically acceptable carboxylate salt and alkyl carboxylate wherein the alkyl moiety has 1 to 6 carbon atoms; and Z 2 is selected from the group consisting of hydrogen and a substituent Z 1 as defined herein.
Claim 2
Independent Claim
83 words
A method of preventing the symptoms of asthma or allergic rhinitis in a mammal having asthma or allergic rhinitis which comprises administering to said mammal a prophylactically effective amount of a compound of formula ##SPC14## where Z 1 is selected from the group consisting of carboxyl, a pharmaceutically acceptable carboxylate salt and alkyl carboxylate wherein the alkyl moiety has 1 to 6 carbon atoms; and Z 2 is selected from the group consisting of hydrogen and a substituent Z 1 as defined herein.
Claim 3
Independent Claim
74 words
A method of preventing the symptoms of asthma or allergic rhinitis in a mammal having asthma or allergic rhinitis which comprises administering to said mammal a prophylactically effective amount of a compound of the formula ##SPC15## wherein Z 1 and Z 2 are the same or different and each is selected from the group consisting of carboxyl, pharmaceutically acceptable carboxylate salt, and alkyl carboxylate having 1 to 6 carbon atoms in the `alkyl` moiety.
Claim 4
Independent Claim
74 words
A method of preventing the symptoms of asthma or allergic rhinitis in a mammal having asthma or allergic rhinitis which comprises administering to said mammal a prophylactically effective amount of a compound of the formula ##SPC15## wherein Z 1 and Z 2 are the same or different and each is selected from the group consisting of carboxyl, pharmaceutically acceptable carboxylate salt, and alkyl carboxylate having 1 to 6 carbon atoms in the `alkyl` moiety.
Claim 5
Dependent Claim
34 words
The method as claimed in claim 2 wherein Z 1 is selected from the group consisting of carboxyl and pharmaceutically acceptable carboxylate salt, and Z 2 is selected from Z 1 as defined herein.
Claim 6
Dependent Claim
38 words
The method as claimed in claim 3 wherein the carboxylate salt is selected from the group consisting of potassium, sodium, calcium, magnesium, ammonium and organic base salts selected from the group consisting of triethanolamine, diethylaminoethylamine, piperazine and morpholine.
Claim 7
Dependent Claim
13 words
The method according to claim 1 wherein the compound is administered by inhalation.
Claim 8
Dependent Claim
28 words
The method according to claim 5 wherein the compound is administered in the form of a powder having a particle size in the range from 0.5 to 7μ.
Claim 9
Dependent Claim
25 words
The method according to claim 1 wherein the amount of the compound is from 2 μg. to 100 mg. per Kg. bodyweight of said mammal.
Claim 10
Dependent Claim
25 words
The method according to claim 1 wherein the amount of the compound is from 20 μg to 0.2 mg. per kg. bodyweight of said mammal.
Claim 11
Dependent Claim
13 words
The method according to claim 1 wherein the asthma condition is extrinsic asthma.
Claim 12
Dependent Claim
12 words
The method according to claim 1 wherein the condition is allergic rhinitis.
Claim 13
Dependent Claim
11 words
The method of claim 1 wherein said compound is disodium anthraquinone-2,6-dicarboxylate.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-02-16 | 1979-08-18 | 1980-02-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-02-16 | 1983-08-18 | 1984-02-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-02-16 | 1987-08-18 | 1988-02-17 | $7700.00 | Window Closed / Lapsed |