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2-(2-Methyl-5-nitro-1-imidazolyl)ethyl-N-arylalkyldithiocarbamates

Assignee: GD Searle LLC
•
Filing: 1973-10-29
•
Granted: 1975-10-07
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Expires: 1993-10-29
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Abstract

Abstract 2-(2-Methyl-5-nitro-1-imidazolyl)ethyl esters of Narylalkyldithiocarbamates of the formula wherein n is an integer from 1 to 7, R1 is hydrogen or lower alkyl, and R2 is hetero or carbomonocyclicaryl. These compounds are anti-microbial agents. The compounds are prepared in 2 steps. The reaction of the appropriate amine with carbon disulfide in aqueous base forms the dithiocarbamate salt and the final products are formed by the reaction of this salt with 1-(2chloroethyl)-2-methyl-5-nitroimidazole.

Inventors

  • 👤 Eunice M Kreider

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 23:36
CPC Classifications
C; C07; C07D; C07D233/00; C07D233/54; C07D233/66; C07D233/91; C07D233/92; C07D233/94

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 5 words
A COMPOUND OF THE FORMULA
Claim 2
Dependent Claim 5 words
A COMPOUND OF THE FORMULA
Claim 3
Dependent Claim 10 words
According to claim 1, the compound which is 2-(2methyl-5-nitro-5-nitro-1-imidazolyl)ethyl-N-3,4 -dichlorobenzyldithiocarbamate.
Claim 4
Dependent Claim 9 words
According to claim 1, the compound which is 2-(2-methyl-5-nitro-1-imidazolyl)ethyl-N-p-chlorobenzyldithiocarbamate.
Claim 5
Dependent Claim 9 words
According to claim 1, the compound which is 2-(2-methyl-5-nitro-1-imidazolyl)ethyl-N-p-methoxybenzyldithiocarbamate.
Claim 6
Dependent Claim 9 words
According to claim 1, the compound which is 2-(2-methyl-5-nitro-1-imidazolyl)ethyl-N-3,4-dimethoxybenzyldithiocarbamate.
Claim 7
Dependent Claim 9 words
According to claim 1, the compound which is 2-(2-methyl-5-nitro-1-imidazolyl)ethyl-N-o-fluorobenzyldithiocarbamate.
Claim 8
Dependent Claim 9 words
According to claim 1, the compound which is 2-(2-methyl-5-nitro-1-imidazolyl)ethyl-N-m-methylbenzyldithiocarbamate.
Claim 9
Dependent Claim 9 words
According to claim 1, the compound which is 2-(2-methyl-5-nitro-1-imidazolyl)ethyl-N-furfuryldithiocarbamate.
Claim 10
Dependent Claim 9 words
According to claim 1, the compound which is 2-(2-methyl-5-nitro-1-imidazolyl)ethyl-N-p-chlorophenethyldithiocarbamate.
Claim 11
Dependent Claim 9 words
According to claim 1, the compound which is 2-(2-methyl-5-nitro-2-imidazolyl)ethyl-N-p-methoxyphenethyldithiocarbamate.
Claim 12
Dependent Claim 9 words
According to claim 1, the compound which is 2-(2-methyl-5-nitro-1-imidazolyl)ethyl-N-methyl-N-benzyldithiocarbamate.

References Cited (Backward Citations)

US3696116A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-10-06 1979-04-07 1979-10-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-10-06 1983-04-07 1983-10-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-10-06 1987-04-07 1987-10-07 $7700.00 Window Closed / Lapsed

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