Patent US3901876A successfully refreshed from Google Patents.
US3901876A
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Adenosine derivatives
Assignee: Bayer Pharma AG
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Filing: 1972-09-14
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Granted: 1975-08-26
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Expires: 1992-09-14
Abstract
Abstract Adenosine derivatives of the formula WHEREIN A is saturated or unsaturated, straight-chain, branched or cyclic alkylene optionally substituted by one of hydroxy, acyloxy, carboxy or acyl; X is a valence bond, oxygen, sulfur, or an alkylated or acylated imino group; and B is 3-indolyl or 4imidazolyl optionally substituted by one or more of halogen, alkyl, haloalkyl, alkoxy, aryloxy, acyloxy, hydroxy, mercapto, alkylmercapto, nitro, carboxy, carboxyalkyl, or methylsulfonylamino, and processes for their preparation and use. These adenosine derivatives exert pharmacological effects on the central nervous system, the circulation, and the heart.
Inventors
- 👤 Helmut Vorbruggen
- 👤 Rudolf Kopp
- 👤 Reinhard Horowski
- 👤 Gert Paschelke
- 👤 Dieter Palenschat
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 13:11
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/16
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
5 words
ADENOSINE DERIVATIVES OF THE FORMULA
Claim 2
Dependent Claim
5 words
ADENOSINE DERIVATIVES OF THE FORMULA
Claim 3
Dependent Claim
16 words
A compound according to claim 1, wherein A is linear saturated alkylene of 1-8 carbon atoms.
Claim 4
Dependent Claim
12 words
A compound according to claim 1, wherein X is a valence bond.
Claim 5
Dependent Claim
23 words
A compound according to claim 1, wherein B is unsubstituted indolyl or indolyl substituted at one or both of the 2- and 5-positions.
Claim 6
Dependent Claim
15 words
A compound according to claim 4, wherein B is substituted by hydroxy or lower alkoxy.
Claim 7
Dependent Claim
12 words
A compound according to claiM 4, wherein X is a valence bond.
Claim 8
Dependent Claim
16 words
A compound according to claim 4, wherein A is linear saturated alkylene of 1-8 carbon atoms.
Claim 9
Dependent Claim
23 words
A compound according to claim 1, wherein B is unsubstituted imidazolyl or imidazolyl substituted at one or both of the 1- and 5-positions.
Claim 10
Dependent Claim
15 words
A compound according to claim 8, wherein B is substituted by hydroxy or lower alkoxy.
Claim 11
Dependent Claim
12 words
A compound according to claim 8, wherein X is a valence bond.
Claim 12
Dependent Claim
16 words
A compound according to claim 8, wherein A is linear saturated alkylene of 1-8 carbon atoms.
Claim 13
Dependent Claim
9 words
A compound of claim 1, N6-( Beta -indolyl-3-ethyl) adenosine.
Claim 14
Dependent Claim
9 words
A compound of claim 1, N6-( Beta -(5-hydroxyindolyl-3)-ethyl) adenosine.
Claim 15
Dependent Claim
9 words
A compound of claim 1, N6-( Beta -(5-methoxyindolyl-3)-ethyl) adenosine.
Claim 16
Dependent Claim
9 words
A compound of claim 1, N6-( Beta -imidazolyl-4-ethyl) adenosine.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-08-25 | 1979-02-24 | 1979-08-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-08-25 | 1983-02-24 | 1983-08-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-08-25 | 1987-02-24 | 1987-08-26 | $7700.00 | Window Closed / Lapsed |