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US3890101A Expired / Lapsed US ⏱️ 0.0 years remaining

Collection ring for use in multiple-sample blood fractionation centrifugal rotors

Assignee: United States Department of Energy
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Filing: 1974-02-15
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Granted: 1975-06-17
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Expires: 1994-02-15
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Abstract

Abstract An improved sample collection ring which comprises a removable annular vial holder ring defining passageways for receiving multiple blood fractions discharged from a central blood fractionation rotor and passing them to respective collection vials. The collection vials sealably and detachably engage respective nipples defined by and integral with the vial holder ring. O-ring seals prevent leakage from the collection vials and assist in the vial-nipple engagement.

Inventors

  • 👤 Thomas O Tiffany
  • 👤 William A Walker
  • 👤 Wayne F Johnson

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 12:17
CPC Classifications
G; G01; G01N; G01N21/00; G01N21/01; G01N21/03; G01N21/07

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 195 words
AN IMPROVED SAMPLE COLLECTION RING FOR USE IN MULTIPLESAMPLE BLOOD FRACTIONATION CENTRIFUGAL ROTORS CHARACTERIZED BY A CENTRAL ROTOR PORTION FOR PREPARING BLOOD FRACTIONS HAVING A MULTIPLICITY OF CIRCUMFERENTIAL DISCHARGE PORTS, SAID COLLECTION RING COMPRISING: I. A REMOVABLE ANNULAR VIAL HOLDER RING HAVING A TOP SURFACE AND A BOTTOM SURFACE NESTED CONCENTRICALLY ABOUT SAID CENTRAL ROTOR PORTION, SAID VIAL HOLDER RING DEFINING: A. FIRST AND SECOND NIPPLES POSITIONED ALTERNATIVELY IN A CIRCULAR ARRAY, SAID NIPPLES DEPENDING FROM THE BOTTOM SIDE OF SAID VIAL HOLDER RING, B. A FIRST ARRAY OF PASAGEWAYS HAVING CENTRIPETAL ENDS OPENING IN REGISTER WITH SAID CIRCUMFERENTIAL DISCJARGE PORTS AND CENTRIFUGAL ENDS OPENING IN THE BOTTOM ENDS OF SAID FIRST NIPPLES, C. A SECOND ARRAY OF PASSAGEWAYS COMMUNICATING BETWEEN AND OPOPENING IN THE BOTTOM ENDS OF PAIRS OF SAID FIRST AND SECOND NIPPLES, AND D. A THIRD ARAY OF PASSAGEWAYS HAVING CENTRIFUGAL ENDS OPENING IN THE BOTTOM ENDS OF SAID SECOND NIPPLES AND CENTRIPETAL ENDS OPENING IN SAID TOP SURFACE OF SAID VIAL HOLDER RING, II. PRIMARY AND SECONDARY SAMPLE COLLECTION VIALS REMOVABLY ATTACHED TO SAID FIRST AND SECOND NIPLES, RESPECTIVELY, AND II. MEANS FOR SEALING SAID SAMPLE COLLECTION VIALS TO SAID NIPPLES.
Claim 2
Dependent Claim 195 words
AN IMPROVED SAMPLE COLLECTION RING FOR USE IN MULTIPLESAMPLE BLOOD FRACTIONATION CENTRIFUGAL ROTORS CHARACTERIZED BY A CENTRAL ROTOR PORTION FOR PREPARING BLOOD FRACTIONS HAVING A MULTIPLICITY OF CIRCUMFERENTIAL DISCHARGE PORTS, SAID COLLECTION RING COMPRISING: I. A REMOVABLE ANNULAR VIAL HOLDER RING HAVING A TOP SURFACE AND A BOTTOM SURFACE NESTED CONCENTRICALLY ABOUT SAID CENTRAL ROTOR PORTION, SAID VIAL HOLDER RING DEFINING: A. FIRST AND SECOND NIPPLES POSITIONED ALTERNATIVELY IN A CIRCULAR ARRAY, SAID NIPPLES DEPENDING FROM THE BOTTOM SIDE OF SAID VIAL HOLDER RING, B. A FIRST ARRAY OF PASAGEWAYS HAVING CENTRIPETAL ENDS OPENING IN REGISTER WITH SAID CIRCUMFERENTIAL DISCJARGE PORTS AND CENTRIFUGAL ENDS OPENING IN THE BOTTOM ENDS OF SAID FIRST NIPPLES, C. A SECOND ARRAY OF PASSAGEWAYS COMMUNICATING BETWEEN AND OPOPENING IN THE BOTTOM ENDS OF PAIRS OF SAID FIRST AND SECOND NIPPLES, AND D. A THIRD ARAY OF PASSAGEWAYS HAVING CENTRIFUGAL ENDS OPENING IN THE BOTTOM ENDS OF SAID SECOND NIPPLES AND CENTRIPETAL ENDS OPENING IN SAID TOP SURFACE OF SAID VIAL HOLDER RING, II. PRIMARY AND SECONDARY SAMPLE COLLECTION VIALS REMOVABLY ATTACHED TO SAID FIRST AND SECOND NIPLES, RESPECTIVELY, AND II. MEANS FOR SEALING SAID SAMPLE COLLECTION VIALS TO SAID NIPPLES.
Claim 3
Dependent Claim 23 words
The improved sample collection ring of claim 1 wherein the centripetal ends of passageways in said first array of passageways have enlarged ends.
Claim 4
Dependent Claim 27 words
The improved sample collection ring of claim 1 wherein said means for sealing said sample collection vials to said nipples comprises O-rings extending circumferentially about said nipples.
Claim 5
Dependent Claim 167 words
An improved sample collection ring for use in multiple-sample blood fractionation centrifugal rotors characterized by a central rotor portion for preparing blood fractions having a multiplicity of circumferential discharge ports; said collection ring comprising: i. a removable annular vial holder ring having a top surface and a bottom surface nested concentrically about said central rotor portion, said vial holder ring defining: a. a circular array of nipples equal in number to said discharge ports, said nipples depending from the bottom side of said vial holder ring; b. a first array of passageways having centripetal ends opening in register with said discharge ports and centrifugal ends opening in the bottom ends of said nipples; and c. a second array of passageways having centrifugal ends opening in the bottom ends of said nipples and centripetal ends opening in said top surface of said vial holder ring; ii. sample collection vials removably attached to each of said nipples; and iii. means for sealing said sample collection vials to said nipples.
Claim 6
Dependent Claim 167 words
An improved sample collection ring for use in multiple-sample blood fractionation centrifugal rotors characterized by a central rotor portion for preparing blood fractions having a multiplicity of circumferential discharge ports; said collection ring comprising: i. a removable annular vial holder ring having a top surface and a bottom surface nested concentrically about said central rotor portion, said vial holder ring defining: a. a circular array of nipples equal in number to said discharge ports, said nipples depending from the bottom side of said vial holder ring; b. a first array of passageways having centripetal ends opening in register with said discharge ports and centrifugal ends opening in the bottom ends of said nipples; and c. a second array of passageways having centrifugal ends opening in the bottom ends of said nipples and centripetal ends opening in said top surface of said vial holder ring; ii. sample collection vials removably attached to each of said nipples; and iii. means for sealing said sample collection vials to said nipples.
Claim 7
Dependent Claim 27 words
The improved sample collection ring of claim 4 wherein said means for sealing said sample collection vials to said nipples comprises O-rings extending circumferentially about said nipples.

References Cited (Backward Citations)

US3547547A Cited
US3744975A Cited
US3798459A Cited
US3795451A Cited
US3829223A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-06-16 1978-12-16 1979-06-17 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-06-16 1982-12-16 1983-06-17 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-06-16 1986-12-16 1987-06-17 $7700.00 Window Closed / Lapsed

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