Patent US3880739A successfully refreshed from Google Patents.
US3880739A
Expired / Lapsed
US
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Enzyme catalyzed oxidations of hydrocarbons
Assignee: Mobil Oil AS
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Filing: 1973-01-04
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Granted: 1975-04-29
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Expires: 1993-01-04
Abstract
Abstract The known oxidation of long chain normal paraffins by oxygen to oxygenated derivatives, notably aldehydes, in the presence of enzymes which are per se known to catalyze this oxidation is improved by operating in a water (enzyme phase) in oil (paraffin phase) emulsion system, adding a non-ionic surfactant; feeding enzyme which has been recovered from parent cells in the presence of paraffin; and utilizing a semipermeable membrane to separate the oil phase, including product, from the enzyme-containing water phase.
Inventors
- 👤 Richard I Leavitt
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 07:54
CPC Classifications
B; B01; B01D; B01D61/00; B01D61/02; B01D67/00; B01D67/0081; B01D67/0088; B01D71/00; B01D71/06; B01D71/66; C; C12; C12P; C12P1/00; C12P7/00; C12P7/24
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
125 words
IN THE OXYGEN OXIDATION OF A HYDROPHOBIC REACTANT COMPRISING AT LEAST ONE PARAFFIN, OR PARTIALLY OXYGENATED DERIVATIVE THEREOF, BY CONTACTING OXYGEN, SAID HYDROPHOBIC REACTANT AND AN AQUEOUS SYSTEM CONTAINING AT LEAST ONE ENZYME CAPABLE OF CARALYZING THIS OXIDATION UNDER REACTION CONSITIONS SUFFICIENT TO SUPPORT SAID OXIDATION; THE IMPROVEMENT WHICH COMPRISES PROVIDING AS A REACTION MASS SAID HYDROPHOBIC REACTANT IN A CONTINUOUS HYDROPHOBIC PHASE AND SAID ENZYME IN A DISCONTINUOUS AQUEOUS PHASE ENVELOPED BY SAID CONTINUOUS HYDROPHOBIC PHASE; PROVIDING A HYDROPHOBIC PHASE PERMEABLE-AQUEOUS ENZYME SOLUTION IMPERMAEABLE SEMI-PERMEABLE MEMBRANE; CONTACTING SAID REACTION MASS WITH SAID SEM-PERMEABLE MEMBRANE UNDER SUCH TEMPERATURE AND PRESSURE CONDITIONS AS TO PASS SAID HYDROPHOBIC PHASE CONTAINING SIAD HIGHER OXYGENATED DERIVATIVE PRODUCT THERETHROUGH; AND RECOVERING SAID HIGHER OXYGENATED DERIVATIVE FROM SAID PASSED HYDRPHHOBIC PHASE.
Claim 2
Dependent Claim
125 words
IN THE OXYGEN OXIDATION OF A HYDROPHOBIC REACTANT COMPRISING AT LEAST ONE PARAFFIN, OR PARTIALLY OXYGENATED DERIVATIVE THEREOF, BY CONTACTING OXYGEN, SAID HYDROPHOBIC REACTANT AND AN AQUEOUS SYSTEM CONTAINING AT LEAST ONE ENZYME CAPABLE OF CARALYZING THIS OXIDATION UNDER REACTION CONSITIONS SUFFICIENT TO SUPPORT SAID OXIDATION; THE IMPROVEMENT WHICH COMPRISES PROVIDING AS A REACTION MASS SAID HYDROPHOBIC REACTANT IN A CONTINUOUS HYDROPHOBIC PHASE AND SAID ENZYME IN A DISCONTINUOUS AQUEOUS PHASE ENVELOPED BY SAID CONTINUOUS HYDROPHOBIC PHASE; PROVIDING A HYDROPHOBIC PHASE PERMEABLE-AQUEOUS ENZYME SOLUTION IMPERMAEABLE SEMI-PERMEABLE MEMBRANE; CONTACTING SAID REACTION MASS WITH SAID SEM-PERMEABLE MEMBRANE UNDER SUCH TEMPERATURE AND PRESSURE CONDITIONS AS TO PASS SAID HYDROPHOBIC PHASE CONTAINING SIAD HIGHER OXYGENATED DERIVATIVE PRODUCT THERETHROUGH; AND RECOVERING SAID HIGHER OXYGENATED DERIVATIVE FROM SAID PASSED HYDRPHHOBIC PHASE.
Claim 3
Dependent Claim
35 words
The improved process claimed in claim 1 wherein said hydrophobic reactant phase includes a normal alcohol of about 12 to 18 carbon atoms and said oxygenated derivative is a C12 to C18 normal alkyl aldehyde.
Claim 4
Dependent Claim
21 words
The improved process claimed in claim 2 wherein the principal aldehyde product corresponds in chain length and configuration to said alkanol.
Claim 5
Dependent Claim
23 words
The improved process claimed in claim 3 wherein said hydrophobic reactant phase includes said alkanol and a paraffin of the same chain length.
Claim 6
Dependent Claim
21 words
The improved process claimed in claim 4 wherein said paraffin is n-tetradecane, said alcohol is n-tetradecanol and said aldehyde is n-tetradecanal.
Claim 7
Dependent Claim
10 words
The improved process claimed in claim 1 carried out continuously.
Claim 8
Dependent Claim
16 words
The improved process claimed in claim 1 wherein said enzymes are derived from Pichia yeast cells.
Claim 9
Dependent Claim
39 words
The improved process claimed in claim 1 wherein said reactant comprises a paraffin and said product comprises an oxygenated derivative thereof, and wherein said aqueous enzyme solution is substantially immiscible with said paraffin reactant and said oxygenated derivative thereof.
Claim 10
Dependent Claim
24 words
The improved process claimed in claim 1 wherein the reaction mass comprises an emulsion of said aqueous enzyme phase in said hydrophobic reactant phase.
Claim 11
Dependent Claim
16 words
A process as claimed in claim 1 including recycling unreacted portions of said hydrophobic reactant phase.
Claim 12
Dependent Claim
70 words
A process as claimed in claim 1 wherein said semi-permeable membranes comprises a thermoplastic polymer having about 5 To 50 percent crystallinity, a glass transition temperature of at least about 20*C and a water absorptivity of less than about 10 percent at 25*C and 100 percent relative humidity, and wherein said membrane has been dried and had its pores filed with a hydrophobic liquid prior to use in said process.
Claim 13
Dependent Claim
15 words
A process as claimed in claim 1 including providing a surfactant in the reaction system.
Claim 14
Dependent Claim
12 words
A process as claimed in claim 1 including agitating the reaction system.
Claim 15
Dependent Claim
21 words
The improved process of claim 1 wherein said continuous hydrophobic phase contains a material which is miscible with said organic compound.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-04-28 | 1978-10-28 | 1979-04-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-04-28 | 1982-10-28 | 1983-04-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-04-28 | 1986-10-28 | 1987-04-29 | $7700.00 | Window Closed / Lapsed |