Patent US3801783A successfully refreshed from Google Patents.
US3801783A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Apparatus for screening cytological specimens
Assignee: Information Utilization Corp
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Filing: 1971-07-22
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Granted: 1974-04-02
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Expires: 1991-07-22
Abstract
Abstract A slide specimen of exfoliated cells is prepared in the usual manner for microscopic optical examination of a Papanicloaou Test, up to the point of staining. At this stage, instead of the ordinary stains, a stain containing a radioisotope is used. The slide with the radioisotope-bearing stain is thereupon passed through a radiation counter which gives an indication of the amount of radiation the slide emits, which indicates the amount of radioactive stain absorbed by the specimen. This relative absorption amount indicates the differential staining of the cellular material and forms the equivalent electronic differentiation of the specimens to the standard Papanicolaou optical differentiation as viewed through the microscope. In this way, the automatic radiation counter is used to substitute for the human element in the microscopic evaluation of the specimens.
Inventors
- 👤 L Caiola
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 17:31
CPC Classifications
G; G01; G01N; G01N1/00; G01N1/28; G01N1/30; G01T; G01T7/00; G01T7/08; G02; G02B; G02B21/00; G02B21/34; Y; Y10; Y10S; Y10S435/00; Y10S435/808
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
72 words
In an apparatus for analyzing specimens for the Pap Test using exfoliated or tissue biopsy cells, the combination of means for preparing a specimen and for applying a biological stain containing a radioactive material to the specimen, means for ascertaining the radioactive level of a specimen as a quantitative indication of the uptake of the cells therein of radioactive material, and means for sorting the specimens according to the radioactive levels thereof.
Claim 2
Dependent Claim
72 words
In an apparatus for analyzing specimens for the Pap Test using exfoliated or tissue biopsy cells, the combination of means for preparing a specimen and for applying a biological stain containing a radioactive material to the specimen, means for ascertaining the radioactive level of a specimen as a quantitative indication of the uptake of the cells therein of radioactive material, and means for sorting the specimens according to the radioactive levels thereof.
Claim 3
Dependent Claim
38 words
In an apparatus as claimed in claim 1 wherein there is a centrifuge means for acting upon specimens in solution so that a residue is obtained therefrom which residue is fed to the means for preparing the specimen.
Claim 4
Dependent Claim
20 words
In an apparatus as claimed in claim 1 and means for recording the results of the radioactive levels of specimens.
Claim 5
Dependent Claim
14 words
In an apparatus as claimed in claim 1 wherein there is a cell counter.
Claim 6
Dependent Claim
16 words
In an apparatus as claimed in claim 3 wherein said recording means comprises a digital computer.
Claim 7
Dependent Claim
52 words
In an apparatus as claimed in claim 5, wherein the ascertaining means includes means for generating an output signal corresponding to the radioactive level of each of said specimens, and further comprising an output readout unit connected to said computer for receiving said output signal and for furnishing data to said computer.
Claim 8
Dependent Claim
45 words
In an apparatus as claimed in claim 2 and conveyor means for transferring said specimens between said centrifuge, preparing and staining means and ascertaining means, and including means for delivering data corresponding to the radioactive levels of each of said specimens to said sorting means.
Claim 9
Dependent Claim
20 words
In an apparatus as claimed in claim 6 with said counter having a conveyor upon which said specimens are positioned.
Claim 10
Dependent Claim
39 words
In an apparatus as claimed in claim 6 with said means for ascertaining the radioactive level having a conveyor for moving specimens therethrough, a holder for each specimen, and means on said conveyor for retaining said specimen holders thereon.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-04-01 | 1977-10-01 | 1978-04-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-04-01 | 1981-10-01 | 1982-04-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-04-01 | 1985-10-01 | 1986-04-02 | $7700.00 | Window Closed / Lapsed |