Patent US3666749A successfully refreshed from Google Patents.
US3666749A
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Iron dextran complex and process for making same
Assignee: Rosco AS
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Filing: 1969-09-15
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Granted: 1972-05-30
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Expires: 1989-09-15
Abstract
Abstract A method of making iron dextran complexes wherein ferric hydroxide is reacted with dextran or dextran glucosides, precipitating iron dextran into at least two fractions having different iron contents and subjecting one of the fractions of the iron dextran formed in the first complexing step to a second complexing step and precipitating the iron dextran into at least two fractions having different iron contents, separating and recovering the fraction having the higher iron content and recycling the fraction having the lower iron content.
Inventors
- 👤 Jorgen De Musquiz Reumert
- 👤 Ole Gylling-Pedersen
- 👤 Jose Bou Casals
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 22:08
CPC Classifications
A; A61; A61K; A61K33/00; A61K33/24; A61K33/26; A61K31/00; A61K31/28; A61K31/295; C; C08; C08B; C08B37/00; C08B37/0006; C08B37/0009; C08B37/0021
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
56 words
The method of increasing the iron content of iron dextran complexes which comprises reacting an iron dextran complex in an aqueous medium under acid conditions with a formed in situ ferric hydroxide sol and thereafter precipitating less than about one half the iron dextran complex from the reaction mass and separating and recovering the fraction precipitated.
Claim 2
Dependent Claim
16 words
The method according to claim 2 wherein a second fraction is precipitated , separated and recycled.
Claim 3
Dependent Claim
134 words
The process for producing iron dextran complexes which comprises a first complexing step in which ferric hydroxide is reacted under aqueous acid conditions with a dextran compound having an intrinsic viscosity of 0.025 to 0.75 at 25* C and selected from the group dextran and dextran glucosides, precipitating the iron dextran complex into at least two fractions having different iron contents, subjecting one of the fractions of the iron dextran complex formed in the first complexing step to a second complexing step and wherein said iron dextran complex is reacted under aqueous acid conditions with ferric hydroxide, precipitating the iron dextran contained in the reaction mass into at least two fractions having different iron contents, separating and recovering the fraction having the higher iron content and recycling the fraction having the lower iron content.
Claim 4
Dependent Claim
36 words
A process according to claim 4 wherein the fraction of the iron dextran complex formed in the first complexing step that is subjected to the second complexing step is the fraction having the lower iron content.
Claim 5
Dependent Claim
22 words
A process according to claim 4 wherein both of the complexing steps are carried out at a pH of 1.1 to 2.3.
Claim 6
Dependent Claim
30 words
A process according to claim 4 wherein unreacted ferric ions are removed from the complex produced in the first complexing step before it is subjected to the second complexing step.
Claim 7
Dependent Claim
35 words
A process according to claim 4 wherein an aqueous alkaline solution of the iron dextran complex from the first or second complexing steps is autoclaved, cooled and acidified Before fractionally precipitating the iron dextran complex.
Claim 8
Dependent Claim
35 words
A process according to claim 4 wherein an aqueous alkaline solution of the iron dextran complex from the first and second complexing steps is autoclaved, cooled and acidified before fractionally precipitating the iron dextran complex.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-05-30 | 1975-11-29 | 1976-05-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-05-30 | 1979-11-29 | 1980-05-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-05-30 | 1983-11-29 | 1984-05-30 | $7700.00 | Window Closed / Lapsed |