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US20070050014A1 Expired / Lapsed US ⏱️ 0.0 years remaining

Implantable valve

Assignee: Cook Biotech Inc
•
Filing: 2006-08-31
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Granted: —
•
Expires: 2026-08-31
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Abstract

Abstract Described are implantable prosthetic valve devices comprising isolated granulation tissue. Also described are methods of treatment that include implanting at least one of these valves within a body passageway of a patient, for example, within a vein to treat venous insufficiency.

Inventors

  • 👤 Chad Johnson

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 12:45
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/24; A61F2/2475; A61F2/2412; A61F2/2415

Claims Analysis

Total Claims: 54
Claim 1
Independent Claim 19 words
1 . An implantable valve for modifying fluid flow in a body passageway, said valve comprising isolated granulation tissue.
Claim 2
Dependent Claim 19 words
1 . An implantable valve for modifying fluid flow in a body passageway, said valve comprising isolated granulation tissue.
Claim 3
Dependent Claim 16 words
2 . The valve of claim 1 , wherein said isolated granulation tissue includes mesothelial cells.
Claim 4
Dependent Claim 15 words
3 . The valve of claim 1 , wherein said isolated granulation tissue includes myofibroblasts.
Claim 5
Dependent Claim 15 words
4 . The valve of claim 1 , wherein said isolated granulation tissue is decellularized.
Claim 6
Dependent Claim 19 words
5 . The valve of claim 1 , wherein said isolated granulation tissue is formed in a body cavity.
Claim 7
Dependent Claim 16 words
6 . The valve of claim 5 , wherein said body cavity is in a human.
Claim 8
Dependent Claim 22 words
7 . The valve of claim 5 , wherein said body cavity is in a human patient to receive said implantable valve.
Claim 9
Dependent Claim 12 words
8 . The valve of claim 1 which is a monocusp valve.
Claim 10
Dependent Claim 12 words
9 . The valve of claim 1 which is a multicuspid valve.
Claim 11
Dependent Claim 12 words
10 . The valve of claim 1 which is a bicuspid valve.
Claim 12
Dependent Claim 12 words
11 . The valve of claim 1 which is a tricuspid valve.
Claim 13
Dependent Claim 14 words
12 . The valve of claim 1 configured for implantation as a vascular valve.
Claim 14
Dependent Claim 14 words
13 . The valve of claim 1 configured for implantation as a heart valve.
Claim 15
Dependent Claim 14 words
14 . The valve of claim 1 configured for implantation as a venous valve.
Claim 16
Dependent Claim 13 words
15 . The valve of claim 1 , wherein said valve is frameless.
Claim 17
Dependent Claim 15 words
16 . The valve of claim 1 in combination with at least one frame element.
Claim 18
Dependent Claim 17 words
17 . The valve of claim 16 , wherein said at least one frame element is collapsible.
Claim 19
Dependent Claim 17 words
18 . The valve of claim 16 , wherein said at least one frame element is bioresorbable.
Claim 20
Dependent Claim 19 words
19 . The valve of claim 16 , wherein said at least one frame element comprises a metallic material.
Claim 21
Dependent Claim 23 words
20 . The valve of claim 1 , wherein said valve includes adaptations to attach said valve to walls of said body passageway.
Claim 22
Dependent Claim 40 words
21 . A method of forming an implantable valve cusp for modifying fluid flow in a body passageway, comprising: inserting a cusp-forming device into a body cavity; removing the cusp-forming device from the body cavity after tissue has formed thereon.
Claim 23
Dependent Claim 40 words
21 . A method of forming an implantable valve cusp for modifying fluid flow in a body passageway, comprising: inserting a cusp-forming device into a body cavity; removing the cusp-forming device from the body cavity after tissue has formed thereon.
Claim 24
Dependent Claim 16 words
22 . The method of claim 21 , wherein said cusp-forming device comprises a three-dimensional body.
Claim 25
Dependent Claim 19 words
23 . The method of claim 21 , wherein at least a portion of said cusp-forming device is non-planar.
Claim 26
Dependent Claim 16 words
24 . The method of claim 21 , wherein said cusp-forming device comprises a synthetic polymer.
Claim 27
Dependent Claim 16 words
25 . The method of claim 21 , wherein said cusp-forming device comprises a mesh material.
Claim 28
Dependent Claim 16 words
26 . The method of claim 21 , wherein said cusp-forming device comprises a metallic material.
Claim 29
Dependent Claim 18 words
27 . The method of claim 21 , wherein said cusp-forming device comprises at least one frame element.
Claim 30
Dependent Claim 17 words
28 . The method of claim 21 , wherein said body cavity is that of a vertebrate.
Claim 31
Dependent Claim 17 words
29 . The method of claim 21 , wherein said body cavity is that of a human.
Claim 32
Dependent Claim 21 words
30 . The method of claim 21 , wherein said body cavity is that of a bovine, equine, ovine, or porcine.
Claim 33
Dependent Claim 16 words
31 . The method of claim 21 , wherein said body cavity is a peritoneal cavity.
Claim 34
Dependent Claim 22 words
32 . The method of claim 21 , wherein the cusp-forming device is removed from and/or inserted into the body cavity laparoscopically.
Claim 35
Dependent Claim 14 words
33 . The method of claim 21 , wherein said tissue includes granulation tissue.
Claim 36
Dependent Claim 14 words
34 . The method of claim 21 , wherein said tissue comprises mesothelial cells.
Claim 37
Dependent Claim 13 words
35 . The method of claim 21 , wherein said tissue comprises myofibroblasts.
Claim 38
Dependent Claim 26 words
36 . The method of claim 21 , wherein the cusp-forming device is removed from the body cavity at least 15 days after being inserted therein.
Claim 39
Dependent Claim 27 words
37 . The method of claim 21 , wherein the cusp-forming device is removed from the body cavity no later than 45 days after being inserted therein.
Claim 40
Dependent Claim 28 words
38 . The method of claim 21 , further comprising manipulating said cusp-forming device and/or said tissue after removing said device and said tissue from said body cavity.
Claim 41
Dependent Claim 24 words
39 . The method of claim 38 , wherein said manipulating comprises separating at least a portion of said tissue from said cusp-forming device.
Claim 42
Dependent Claim 25 words
40 . The method of claim 38 , wherein said manipulating comprises associating said cusp-forming device and/or said tissue with at least one frame element.
Claim 43
Dependent Claim 34 words
41 . The method of claim 38 , wherein said manipulating comprises associating said cusp-forming device and/or said tissue with at least one adaptation for attaching said valve to walls of said body passageway.
Claim 44
Dependent Claim 15 words
42 . The method of claim 38 , wherein said manipulating comprises decellularizing said tissue.
Claim 45
Dependent Claim 38 words
43 . A medical product, comprising: at least one implantable valve for modifying fluid flow in a body passageway, said at least one valve comprising isolated granulation tissue; and a sealed package containing said at least one valve.
Claim 46
Dependent Claim 38 words
43 . A medical product, comprising: at least one implantable valve for modifying fluid flow in a body passageway, said at least one valve comprising isolated granulation tissue; and a sealed package containing said at least one valve.
Claim 47
Dependent Claim 22 words
44 . The medical product of claim 43 , wherein said at least one implantable valve is configured as a venous valve.
Claim 48
Dependent Claim 22 words
45 . The medical product of claim 43 , wherein said at least one implantable valve is configured as a heart valve.
Claim 49
Dependent Claim 30 words
46 . The medical product of claim 43 , wherein said package is configured to maintain said at least one implantable valve in a sterile condition when sterilely packaged therein.
Claim 50
Dependent Claim 28 words
47 . A method of treatment comprising implanting at least one valve within a body passageway of a patient, the at least one valve comprising isolated granulation tissue.
Claim 51
Dependent Claim 28 words
47 . A method of treatment comprising implanting at least one valve within a body passageway of a patient, the at least one valve comprising isolated granulation tissue.
Claim 52
Dependent Claim 28 words
48 . The method of claim 47 , wherein the at least one valve is implanted within a vascular vessel to treat a condition of the vascular system.
Claim 53
Dependent Claim 23 words
49 . The method of claim 47 , wherein the at least one valve is implanted within a vein to treat venous insufficiency.
Claim 54
Dependent Claim 17 words
50 . The method of claim 47 , wherein the at least one valve is implanted percutaneously.

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