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US20050096647A1 Expired / Lapsed US ⏱️ 0.0 years remaining

Selectable eccentric remodeling and/or ablation of atherosclerotic material

Assignee: Boston Scientific Scimed Inc
•
Filing: 2004-09-10
•
Granted: —
•
Expires: 2024-09-10
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Abstract

Abstract A catheter and catheter system for eccentric remodeling and/or removal of atherosclerotic material of a blood vessel of a patient include an elongate flexible catheter body with a radially expandable structure. A plurality of electrodes or other electrosurgical energy delivery surfaces can radially engage atherosclerotic material when the structure expands. An atherosclerotic material detector near the distal end of the catheter body may measure circumferential atherosclerotic material distribution, and a power source selectively energizes the electrodes to eccentrically remodel the measured atherosclerotic material.

Inventors

  • 👤 Tom Steinke
  • 👤 Corbett Stone
  • 👤 Stephen Ross
  • 👤 Brian Kelleher
  • 👤 Raphael Michel
  • 👤 Donald Koenig

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-22 22:08
CPC Classifications
A; A61; A61B; A61B18/00; A61B18/04; A61B18/12; A61B18/14; A61B18/1492; A61B18/18; A61B18/1815; A61B2018/00053; A61B2018/0016; A61B2018/00214; A61B2018/0022; A61B2018/00267; A61B2018/00315; A61B2018/00345; A61B2018/00404; A61B2018/0041; A61B2018/00571; A61B2018/00577; A61B2018/00601; A61B2018/00636; A61B2018/00642; A61B2018/00654; A61B2018/1861; A61B90/00; A61B90/36; A61B90/37; A61B2090/373; A61B2090/374; A61B2090/376; A61B2090/378; A61B2090/3782; A61B2090/3784; A61B2218/00; A61B2218/001; A61B2218/002; A61B2218/007

Claims Analysis

Total Claims: 66
Claim 1
Independent Claim 105 words
1 . A catheter system for eccentric remodeling of atherosclerotic material of a blood vessel of a patient, the system comprising: an elongate flexible catheter body having a proximal end and a distal end with an axis therebetween; a radially expandable structure near the distal end of the catheter body; a plurality of energy delivery surfaces, each energy delivery surface oriented radially when the expandable structure expands; an atherosclerotic material detector disposed for circumferential atherosclerotic material detection; and a power source electrically coupled to the energy delivery surfaces, the power source energizing the energy delivery surfaces so as to eccentrically remodel the detected atherosclerotic material.
Claim 2
Dependent Claim 105 words
1 . A catheter system for eccentric remodeling of atherosclerotic material of a blood vessel of a patient, the system comprising: an elongate flexible catheter body having a proximal end and a distal end with an axis therebetween; a radially expandable structure near the distal end of the catheter body; a plurality of energy delivery surfaces, each energy delivery surface oriented radially when the expandable structure expands; an atherosclerotic material detector disposed for circumferential atherosclerotic material detection; and a power source electrically coupled to the energy delivery surfaces, the power source energizing the energy delivery surfaces so as to eccentrically remodel the detected atherosclerotic material.
Claim 3
Dependent Claim 25 words
2 . The catheter system of claim 1 , wherein the catheter body has a lumen extending between the proximal end and the distal end.
Claim 4
Dependent Claim 28 words
3 . The catheter system of claim 2 , further comprising an aspiration connector in fluid communication with the lumen at the proximal end of the catheter body.
Claim 5
Dependent Claim 45 words
4 . The catheter system of claim 3 , further comprising proximal and distal debris barriers disposed proximally and distally of the energy delivery surfaces, respectively, and an aspiration port disposed between the proximal and distal barriers for removal of debris during atherosclerotic material remodeling.
Claim 6
Dependent Claim 48 words
5 . The catheter system of claim 2 , wherein the atherosclerotic material detector comprises at least one of: an intravascular ultrasound catheter disposed in the lumen; an intravascular optical coherence tomography catheter disposed in the lumen; and an intravascular magnetic resonance imaging catheter disposed in the lumen.
Claim 7
Dependent Claim 31 words
6 . The catheter system of claim 2 , further comprising an irrigation lumen extending between the proximal end of the catheter body and the distal end of the catheter body.
Claim 8
Dependent Claim 28 words
7 . The catheter system of claim 2 , further comprising a restenosis inhibitor advancable distally within the lumen so as to inhibit restenosis of the blood vessel.
Claim 9
Dependent Claim 21 words
8 . The catheter system of claim 7 , wherein the restenosis inhibitor comprises a brachytherapy catheter having a radiation source.
Claim 10
Dependent Claim 31 words
9 . The catheter system of claim 1 , wherein the radially expandable body comprises a plurality of flexible struts, and wherein the energy delivery surfaces define a circumferentially oriented array.
Claim 11
Dependent Claim 84 words
10 . The catheter system of claim 9 , wherein struts of the radially expandable structure have perforations disposed therebetween so as to define an expandable basket, wherein the basket has a proximal portion and a distal portion with an intermediate portion disposed therebetween, the array of electrodes supported along the intermediate portion so as to engage adjacent atherosclerotic material when the basket is expanded within the blood vessel, and further comprising an aspiration port in fluid communication with an interior of the basket.
Claim 12
Dependent Claim 59 words
11 . The catheter system of claim 10 , further comprising a distal membrane deployable within the blood vessel distally of the electrodes so as to inhibit distal movement of debris, and a proximal membrane deployable proximally of the electrodes so as to inhibit proximal movement of the debris, wherein the membranes inhibit blood interaction with the remodeling process.
Claim 13
Dependent Claim 48 words
12 . The catheter system of claim 11 , wherein the distal membrane is supported by the distal portion of the basket so as to expand radially therewith, and wherein the proximal membrane is supported by the proximal portion of the basket so as to expand radially therewith.
Claim 14
Dependent Claim 27 words
13 . The catheter system of claim 12 , wherein at least one of the proximal and distal membranes comprises a balloon axially off-set from the basket.
Claim 15
Dependent Claim 54 words
14 . The catheter system of claim 1 , wherein the electrodes comprise an array of at least 3 selectable electrodes distributed circumferentially about the axis, and a controller coupling the power source to the electrode array for selectively energizing an eccentric subset of the electrode array in response to the detected atherosclerotic material.
Claim 16
Dependent Claim 45 words
15 . The catheter system of claim 14 , wherein each electrode comprises a metallic surface supported by an adjacent strut of the expandable structure with an associated conductor extending proximally of the electrode so as to electrically couple the electrode surface to the controller.
Claim 17
Dependent Claim 33 words
16 . The catheter system of claim 1 , wherein a controller selectively energizes a subset of the energy directing surfaces by directing at least one of RF energy and microwave energy thereto.
Claim 18
Dependent Claim 22 words
17 . The catheter system of claim 1 , wherein the atherosclerotic material detector comprises an ultrasound transducer or optical coherence reflectrometer.
Claim 19
Dependent Claim 34 words
18 . The catheter system of claim 1 , further comprising a display coupled to the atherosclerotic material detector, the display showing an image of circumferential atherosclerotic material thickness distributed about the catheter axis.
Claim 20
Dependent Claim 110 words
19 . A catheter system for eccentric removal of atherosclerotic material from a blood vessel of a patient, the system comprising: an elongate flexible catheter body having a proximal end and a distal end with an axis therebetween; a radially expandable structure near the distal end of the catheter body; a plurality of electrodes oriented to be urged radially against atherosclerotic material when the expandable structure expands; an atherosclerotic material detector disposed near the distal end of the catheter body for circumferential measurement of atherosclerotic material; and a power source electrically coupled to the electrodes, the power source energizing the electrodes so as to eccentrically ablate the measured atherosclerotic material.
Claim 21
Dependent Claim 110 words
19 . A catheter system for eccentric removal of atherosclerotic material from a blood vessel of a patient, the system comprising: an elongate flexible catheter body having a proximal end and a distal end with an axis therebetween; a radially expandable structure near the distal end of the catheter body; a plurality of electrodes oriented to be urged radially against atherosclerotic material when the expandable structure expands; an atherosclerotic material detector disposed near the distal end of the catheter body for circumferential measurement of atherosclerotic material; and a power source electrically coupled to the electrodes, the power source energizing the electrodes so as to eccentrically ablate the measured atherosclerotic material.
Claim 22
Dependent Claim 25 words
20 . The catheter system of claim 19 , wherein the catheter body has a lumen extending between the proximal end and the distal end.
Claim 23
Dependent Claim 28 words
21 . The catheter system of claim 20 , further comprising an aspiration connector in fluid communication with the lumen at the proximal end of the catheter body.
Claim 24
Dependent Claim 45 words
22 . The catheter system of claim 21 , further comprising proximal and distal ablation debris barriers disposed proximally and distally of the electrodes, respectively, and an aspiration port disposed between the proximal and distal barriers for removal of ablation debris during atherosclerotic material ablation.
Claim 25
Dependent Claim 31 words
23 . The catheter system of claim 20 , wherein the atherosclerotic material detector comprises an ultrasound transducer of an intravascular ultrasound catheter, the intravascular ultrasound catheter disposed in the lumen.
Claim 26
Dependent Claim 31 words
24 . The catheter system of claim 20 , further comprising an irrigation lumen extending between the proximal end of the catheter body and the distal end of the catheter body.
Claim 27
Dependent Claim 28 words
25 . The catheter system of claim 20 , further comprising a restenosis inhibitor advancable distally within the lumen so as to inhibit restenosis of the blood vessel.
Claim 28
Dependent Claim 21 words
26 . The catheter system of claim 25 , wherein the restenosis inhibitor comprises a brachytherapy catheter having a radiation source.
Claim 29
Dependent Claim 30 words
27 . The catheter system of claim 19 , wherein the radially expandable body comprises a plurality of flexible struts, and wherein the electrodes define a circumferentially oriented electrode array.
Claim 30
Dependent Claim 85 words
28 . The catheter system of claim 27 , wherein struts of the radially expandable structure have perforations disposed therebetween so as to define an expandable basket, wherein the basket has a proximal portion and a distal portion with an intermediate portion disposed therebetween, an array of electrodes supported along the intermediate portion so as to engage the adjacent atherosclerotic material when the basket is expanded within the blood vessel, and further comprising an aspiration port in fluid communication with an interior of the basket.
Claim 31
Dependent Claim 60 words
29 . The catheter system of claim 28 , further comprising a distal membrane deployable within the blood vessel distally of electrodes so as to inhibit distal movement of ablation debris, and a proximal membrane deployable proximally of the electrodes so as to inhibit proximal movement of the ablation debris, wherein the membranes inhibit blood interaction with the ablation process.
Claim 32
Dependent Claim 48 words
30 . The catheter system of claim 29 , wherein the distal membrane is supported by the distal portion of the basket so as to expand radially therewith, and wherein the proximal membrane is supported by the proximal portion of the basket so as to expand radially therewith.
Claim 33
Dependent Claim 27 words
31 . The catheter system of claim 30 , wherein at least one of the proximal and distal membranes comprises a balloon axially off-set from the basket.
Claim 34
Dependent Claim 55 words
32 . The catheter system of claim 19 , wherein the electrodes comprise an array of at least 6 alternatively selectable electrodes distributed circumferentially about the axis, and a controller coupling the power source to the electrode array for selectively energizing an eccentric subset of the electrode array in response to the measured atherosclerotic material.
Claim 35
Dependent Claim 48 words
33 . The catheter system of claim 32 , wherein each electrode comprises a metallic body affixed to an adjacent strut of the expandable structure by a polymer with an associated conductor extending proximally from the electrode so as to electrically couple the electrode surface to the controller.
Claim 36
Dependent Claim 20 words
34 . The catheter system of claim 32 , wherein the controller selectively energizes electrodes by directing RF energy thereto.
Claim 37
Dependent Claim 22 words
35 . The catheter system of claim 19 , wherein the atherosclerotic material detector comprises an ultrasound transducer or optical coherence reflectrometry.
Claim 38
Dependent Claim 26 words
36 . The catheter system of claim 20 , further comprising a display showing an image of circumferential atherosclerotic material thickness distributed about the catheter axis.
Claim 39
Dependent Claim 113 words
37 . A catheter for remodeling of atherosclerotic material of a blood vessel of a patient, the catheter comprising: an elongate flexible catheter body having a proximal end and a distal end with lumen therebetween; a radially expandable basket near the distal end of the catheter body, the basket having a proximal portion and a distal portion with an intermediate portion disposed therebetween; and a circumferential electrode array distributed circumferentially about the intermediate portion of the radially expandable basket so as to selectably remodel adjacent eccentric atherosclerotic material while the basket is expanded within the blood vessel; an aspiration port providing fluid communication between the aspiration lumen and an interior of the basket.
Claim 40
Dependent Claim 113 words
37 . A catheter for remodeling of atherosclerotic material of a blood vessel of a patient, the catheter comprising: an elongate flexible catheter body having a proximal end and a distal end with lumen therebetween; a radially expandable basket near the distal end of the catheter body, the basket having a proximal portion and a distal portion with an intermediate portion disposed therebetween; and a circumferential electrode array distributed circumferentially about the intermediate portion of the radially expandable basket so as to selectably remodel adjacent eccentric atherosclerotic material while the basket is expanded within the blood vessel; an aspiration port providing fluid communication between the aspiration lumen and an interior of the basket.
Claim 41
Dependent Claim 93 words
38 . The catheter of claim 37 , wherein the catheter body has an aspiration lumen, and further comprising: an aspiration port providing fluid communication between the aspiration lumen and an interior of the basket; and a distal membrane supported by the distal portion of the basket so as to inhibit distal movement of debris when the basket is expanded within the blood vessel, and a proximal membrane supported by the proximal portion of the basket so as to inhibit proximal movement of debris when the basked is expanded within the blood vessel.
Claim 42
Dependent Claim 171 words
39 . A catheter for atherosclerotic material removal from a blood vessel of a patient, the catheter comprising: an elongate flexible catheter body having a proximal end and a distal end with an axial aspiration lumen therebetween; a radially expandable basket near the distal end of the catheter body, the basket having a proximal portion and a distal portion with an intermediate portion disposed therebetween; a circumferential electrode array distributed circumferentially about the intermediate portion of the radially expandable basket so as to ablate adjacent atherosclerotic material when the basket expands within the blood vessel; an aspiration port providing fluid communication between the aspiration lumen and an interior of the basket; and a distal membrane supported by the distal portion of the basket so as to inhibit distal movement of ablation debris when the basket is expanded within the blood vessel, and a proximal membrane supported by the proximal portion of the basket so as to inhibit proximal movement of ablation debris when the basked is expanded within the blood vessel.
Claim 43
Dependent Claim 171 words
39 . A catheter for atherosclerotic material removal from a blood vessel of a patient, the catheter comprising: an elongate flexible catheter body having a proximal end and a distal end with an axial aspiration lumen therebetween; a radially expandable basket near the distal end of the catheter body, the basket having a proximal portion and a distal portion with an intermediate portion disposed therebetween; a circumferential electrode array distributed circumferentially about the intermediate portion of the radially expandable basket so as to ablate adjacent atherosclerotic material when the basket expands within the blood vessel; an aspiration port providing fluid communication between the aspiration lumen and an interior of the basket; and a distal membrane supported by the distal portion of the basket so as to inhibit distal movement of ablation debris when the basket is expanded within the blood vessel, and a proximal membrane supported by the proximal portion of the basket so as to inhibit proximal movement of ablation debris when the basked is expanded within the blood vessel.
Claim 44
Dependent Claim 102 words
40 . A method for remodeling eccentric atherosclerotic material of a blood vessel of a patient, the method comprising: positioning a working end of a catheter within the blood vessel and adjacent the atherosclerotic material, the catheter defining an axis radially expanding the catheter so as to engage at least one energy delivery surface of the catheter against the atherosclerotic material; determining a circumferential distribution of the atherosclerotic material about the axis of the catheter; directing electrosurgical energy from the at least one energy delivery surface eccentrically relative to the axis of the catheter in response to the determined atherosclerotic material distribution.
Claim 45
Dependent Claim 102 words
40 . A method for remodeling eccentric atherosclerotic material of a blood vessel of a patient, the method comprising: positioning a working end of a catheter within the blood vessel and adjacent the atherosclerotic material, the catheter defining an axis radially expanding the catheter so as to engage at least one energy delivery surface of the catheter against the atherosclerotic material; determining a circumferential distribution of the atherosclerotic material about the axis of the catheter; directing electrosurgical energy from the at least one energy delivery surface eccentrically relative to the axis of the catheter in response to the determined atherosclerotic material distribution.
Claim 46
Dependent Claim 48 words
41 . The method of claim 40 , wherein the electrosurgical energy is directed eccentrically without rotating the energy delivery surfaces about the catheter axis by energizing a subset of the electrodes, and further comprising selecting the subset of electrodes in response to the determined atherosclerotic material distribution.
Claim 47
Dependent Claim 20 words
42 . The method of claim 40 , further comprising rotationally registering selected electrodes with the determined atherosclerotic material distribution.
Claim 48
Dependent Claim 28 words
43 . The method of claim 42 , wherein the registration is performed with reference to one or more structures of the expandable basket having a distinguishable image.
Claim 49
Dependent Claim 20 words
44 . The method of claim 42 , wherein the registration is performed automatically with reference to an electronic signal.
Claim 50
Dependent Claim 95 words
45 . A method for eccentric atherosclerotic material removal from a blood vessel of a patient, the method comprising: positioning a working end of a catheter within the blood vessel and adjacent the atherosclerotic material, the catheter defining an axis; radially expanding the catheter so as to engage a plurality of electrodes of the catheter against the atherosclerotic material; measuring a circumferential distribution of the atherosclerotic material about the axis of the catheter; directing RF energy from the electrodes eccentrically relative to the axis of the catheter in response to the measured atherosclerotic material distribution.
Claim 51
Dependent Claim 95 words
45 . A method for eccentric atherosclerotic material removal from a blood vessel of a patient, the method comprising: positioning a working end of a catheter within the blood vessel and adjacent the atherosclerotic material, the catheter defining an axis; radially expanding the catheter so as to engage a plurality of electrodes of the catheter against the atherosclerotic material; measuring a circumferential distribution of the atherosclerotic material about the axis of the catheter; directing RF energy from the electrodes eccentrically relative to the axis of the catheter in response to the measured atherosclerotic material distribution.
Claim 52
Dependent Claim 20 words
46 . The method of claim 45 , further comprising rotationally registering selected electrode with the measured atherosclerotic material distribution.
Claim 53
Dependent Claim 27 words
47 . The method of claim 46 , wherein the registration is performed with reference to a asymmetric structure of the expandable basket having a distinguishable image.
Claim 54
Dependent Claim 20 words
48 . The method of claim 46 , wherein the registration is performed automatically with reference to an electronic signal.
Claim 55
Dependent Claim 100 words
49 . A system for eccentric remodeling of material of a body lumen of a patient, the system comprising: an elongate body having a proximal end and a distal end with an axis therebetween; a radially expandable structure near the distal end of the catheter body; a plurality of electrodes oriented to be urged radially against the material when the expandable structure expands within the body lumen; a material detector disposed for circumferential measurement of the material; and a power source electrically coupled to the electrodes, the power source energizing the electrodes so as to eccentrically remodel the measured material.
Claim 56
Dependent Claim 100 words
49 . A system for eccentric remodeling of material of a body lumen of a patient, the system comprising: an elongate body having a proximal end and a distal end with an axis therebetween; a radially expandable structure near the distal end of the catheter body; a plurality of electrodes oriented to be urged radially against the material when the expandable structure expands within the body lumen; a material detector disposed for circumferential measurement of the material; and a power source electrically coupled to the electrodes, the power source energizing the electrodes so as to eccentrically remodel the measured material.
Claim 57
Dependent Claim 162 words
50 . A device for remodeling occlusive material of a body lumen of a patient, the device comprising: an elongate body having a proximal end and a distal end with an axial aspiration lumen therebetween; a radially expandable basket near the distal end of the body, the basket having a proximal portion and a distal portion with an intermediate portion disposed therebetween; a circumferential electrode array distributed circumferentially about the intermediate portion of the radially expandable basket so as to remodel adjacent occlusive material when the basket expands within the body lumen; an aspiration port providing fluid communication between the aspiration lumen and an interior of the basket; and a distal membrane supported by the distal portion of the basket so as so expand the membrane when the basket is expanded within the body lumen, and a proximal membrane supported by the proximal portion of the basket so as to expand the membrane when the basket is expanded within the body lumen.
Claim 58
Dependent Claim 162 words
50 . A device for remodeling occlusive material of a body lumen of a patient, the device comprising: an elongate body having a proximal end and a distal end with an axial aspiration lumen therebetween; a radially expandable basket near the distal end of the body, the basket having a proximal portion and a distal portion with an intermediate portion disposed therebetween; a circumferential electrode array distributed circumferentially about the intermediate portion of the radially expandable basket so as to remodel adjacent occlusive material when the basket expands within the body lumen; an aspiration port providing fluid communication between the aspiration lumen and an interior of the basket; and a distal membrane supported by the distal portion of the basket so as so expand the membrane when the basket is expanded within the body lumen, and a proximal membrane supported by the proximal portion of the basket so as to expand the membrane when the basket is expanded within the body lumen.
Claim 59
Dependent Claim 108 words
51 . A system for eccentric removal of material from a body lumen of a patient, the system comprising: an elongate body having a proximal end and a distal end with an axis therebetween; a radially expandable structure near the distal end of the catheter body; a plurality of electrodes oriented to be urged radially against the material when the expandable structure expands within the body lumen; a material detector disposed near the distal end of the catheter body for circumferential measurement of the material; and a power source electrically coupled to the electrodes, the power source energizing the electrodes so as to eccentrically ablate the measured material.
Claim 60
Dependent Claim 108 words
51 . A system for eccentric removal of material from a body lumen of a patient, the system comprising: an elongate body having a proximal end and a distal end with an axis therebetween; a radially expandable structure near the distal end of the catheter body; a plurality of electrodes oriented to be urged radially against the material when the expandable structure expands within the body lumen; a material detector disposed near the distal end of the catheter body for circumferential measurement of the material; and a power source electrically coupled to the electrodes, the power source energizing the electrodes so as to eccentrically ablate the measured material.
Claim 61
Dependent Claim 162 words
52 . A device for occlusive material removal from a body lumen of a patient, the device comprising: an elongate body having a proximal end and a distal end with an axial aspiration lumen therebetween; a radially expandable basket near the distal end of the body, the basket having a proximal portion and a distal portion with an intermediate portion disposed therebetween; a circumferential electrode array distributed circumferentially about the intermediate portion of the radially expandable basket so as to ablate adjacent occlusive material when the basket expands within the body lumen; an aspiration port providing fluid communication between the aspiration lumen and an interior of the basket; and a distal membrane supported by the distal portion of the basket so as so expand the membrane when the basket is expanded within the body lumen, and a proximal membrane supported by the proximal portion of the basket so as to expand the membrane when the basked is expanded within the body lumen.
Claim 62
Dependent Claim 162 words
52 . A device for occlusive material removal from a body lumen of a patient, the device comprising: an elongate body having a proximal end and a distal end with an axial aspiration lumen therebetween; a radially expandable basket near the distal end of the body, the basket having a proximal portion and a distal portion with an intermediate portion disposed therebetween; a circumferential electrode array distributed circumferentially about the intermediate portion of the radially expandable basket so as to ablate adjacent occlusive material when the basket expands within the body lumen; an aspiration port providing fluid communication between the aspiration lumen and an interior of the basket; and a distal membrane supported by the distal portion of the basket so as so expand the membrane when the basket is expanded within the body lumen, and a proximal membrane supported by the proximal portion of the basket so as to expand the membrane when the basked is expanded within the body lumen.
Claim 63
Dependent Claim 100 words
53 . A system for eccentric remodeling of material of a body lumen of a patient, the system comprising: an elongate body having a proximal end and a distal end with an axis therebetween; a radially expandable structure near the distal end of the catheter body; a plurality of electrodes oriented to be urged radially against the material when the expandable structure expands within the body lumen; a material detector disposed for circumferential detection of the material; and a power source electrically coupled to the electrodes, the power source energizing the electrodes so as to eccentrically remodel the detected material.
Claim 64
Dependent Claim 100 words
53 . A system for eccentric remodeling of material of a body lumen of a patient, the system comprising: an elongate body having a proximal end and a distal end with an axis therebetween; a radially expandable structure near the distal end of the catheter body; a plurality of electrodes oriented to be urged radially against the material when the expandable structure expands within the body lumen; a material detector disposed for circumferential detection of the material; and a power source electrically coupled to the electrodes, the power source energizing the electrodes so as to eccentrically remodel the detected material.
Claim 65
Dependent Claim 162 words
54 . A device for occlusive material remodeling in a body lumen of a patient, the device comprising: an elongate body having a proximal end and a distal end with an axial aspiration lumen therebetween; a radially expandable basket near the distal end of the body, the basket having a proximal portion and a distal portion with an intermediate portion disposed therebetween; a circumferential electrode array distributed circumferentially about the intermediate portion of the radially expandable basket so as to engage adjacent occlusive material when the basket expands within the body lumen; an aspiration port providing fluid communication between the aspiration lumen and an interior of the basket; and a distal membrane supported by the distal portion of the basket so as so expand the membrane when the basket is expanded within the body lumen, and a proximal membrane supported by the proximal portion of the basket so as to expand the membrane when the basked is expanded within the body lumen.
Claim 66
Dependent Claim 162 words
54 . A device for occlusive material remodeling in a body lumen of a patient, the device comprising: an elongate body having a proximal end and a distal end with an axial aspiration lumen therebetween; a radially expandable basket near the distal end of the body, the basket having a proximal portion and a distal portion with an intermediate portion disposed therebetween; a circumferential electrode array distributed circumferentially about the intermediate portion of the radially expandable basket so as to engage adjacent occlusive material when the basket expands within the body lumen; an aspiration port providing fluid communication between the aspiration lumen and an interior of the basket; and a distal membrane supported by the distal portion of the basket so as so expand the membrane when the basket is expanded within the body lumen, and a proximal membrane supported by the proximal portion of the basket so as to expand the membrane when the basked is expanded within the body lumen.

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