US4862886A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Laser angioplasty
Assignee: Summit Technology Inc
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Filing: 1985-05-08
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Granted: 1989-09-05
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Expires: 2005-05-08
Abstract
Abstract A laser therapy system having improved effectiveness in surgical use, particularly in laser angioplasty, can be formed by employing a pulsed source of radiation. The pulsed energy source is preferably an excimer laser having a coherent beam of ultraviolet radiation and preferably is employed in conjunction with a dye laser to produce an output beam which is tunable over a wide portion of the ultraviolet and visible spectrum. The output beam is coupled via a novel coupling device to an optical fiber disposed within a surgical instrument, for example, a percutaneous catheter. The operative components are sealed in a gas-tight, liquid-tight housing. An electronic controller monitors and adjusts the output energy density, duration, and pulse repetition rate. In operation, a pulsed, high energy beam of extremely short duration is available to remove atherosclerotic plague with less damage to the underlying tissue and less chance of perforating the blood vessel wall.
Inventors
- 👤 Richard H. Clarke
- 👤 Jeffrey M. Isner
- 👤 David F. Muller
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:56
CPC Classifications
G; G02; G02B; G02B6/00; G02B6/24; G02B6/42; G02B6/4296; A; A61; A61B; A61B18/00; A61B18/18; A61B18/20; A61B18/22; A61B18/24; A61B18/245; A61B17/00; A61B2017/00017; A61B2017/00137; A61B2017/00154; A61B2017/00194; A61B17/22; A61B2017/22051; A61B90/00; A61B90/39; G02B2006/4297
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
175 words
A laser therapy system for delivering radiation through a fiber optic waveguide of a catheter, the system comprising: an energy source generating high energy pulsed radiation; a tunable laser optically coupled to the energy source to receive the pulsed radiation therefrom, the tunable laser having a resonant cavity defined by opposing reflectors, at least one of the reflectors being partially transmissive to yield an output beam capable of removing a target tissue by photodecomposition, and means for tuning said output beam over at least a portion of a spectrum ranging from about 300 to about 1000 nanometers; a housing enclosing the energy source and tunable laser and sealing them from the ambient environment; coupling means, secured to the housing and adapted to receive the fiber optic waveguide of the catheter and to focus the output beam into the waveguide; and control means electrically connected to the source and laser for varying the output of the laser within predefined ranges of energy, wavelength and pulse duration in response to conditions encountered during use of the system.
Claim 2
Dependent Claim
175 words
A laser therapy system for delivering radiation through a fiber optic waveguide of a catheter, the system comprising: an energy source generating high energy pulsed radiation; a tunable laser optically coupled to the energy source to receive the pulsed radiation therefrom, the tunable laser having a resonant cavity defined by opposing reflectors, at least one of the reflectors being partially transmissive to yield an output beam capable of removing a target tissue by photodecomposition, and means for tuning said output beam over at least a portion of a spectrum ranging from about 300 to about 1000 nanometers; a housing enclosing the energy source and tunable laser and sealing them from the ambient environment; coupling means, secured to the housing and adapted to receive the fiber optic waveguide of the catheter and to focus the output beam into the waveguide; and control means electrically connected to the source and laser for varying the output of the laser within predefined ranges of energy, wavelength and pulse duration in response to conditions encountered during use of the system.
Claim 3
Dependent Claim
14 words
The system of claim 1 wherein the pulsed energy source is an excimer laser.
Claim 4
Dependent Claim
29 words
The system of claim 1 wherein the tunable laser further comprises a dye laser having a free-flowing liquid dye which is circulated through the resonant cavity of dye laser.
Claim 5
Dependent Claim
22 words
The system of claim 3 wherein the dye laser further includes means for changing the composition of the dye to effect tuning.
Claim 6
Dependent Claim
25 words
The system of claim 1 wherein the output beam has a peak energy density ranging from about 0.2 to about 20 Joules per square centimeter.
Claim 7
Dependent Claim
25 words
The system of claim 1 wherein the output beam has a peak energy density ranging from about 0.5 to about 10 Joules per square centimeter.
Claim 8
Dependent Claim
14 words
The system of claim 1 wherein the wavelength is greater than about 307 nanometers.
Claim 9
Dependent Claim
22 words
The system of claim 1 wherein the pulse duration of the output beam ranges from about 5 nanoseconds to about 100 nanoseconds.
Claim 10
Dependent Claim
19 words
The system of claim 8 wherein the period between pulses ranges from about 1 millisecond to about 1 second.
Claim 11
Dependent Claim
61 words
The system of claim 1 wherein the system further comprises an imaging system having an image detecting element also disposed with said catheter and an image processing means for processing an image from said image detecting element, whereby said image is available to an operator of said laser therapy system for guidance of said catheter and adjustment of said control means.
Claim 12
Dependent Claim
14 words
The system of claim 10 wherein the imaging system is an optical imaging system.
Claim 13
Dependent Claim
14 words
The system of claim 10 wherein the imaging system is an echographic imaging system.
Claim 14
Dependent Claim
14 words
The system of claim 10 wherein the imaging system is a photoacoustic imaging system.
Claim 15
Dependent Claim
135 words
A coupling device for use in a laser therapy system employing a fiber optic waveguide disposed within a catheter to transmit a beam of radiation from said laser therapy system to a patient, the coupling device comprising: a receptacle hermetically sealed to the laser system having an opening adapted to receive the waveguide; fastening means for releasably fastening the waveguide in a precise position in the receptacle during use and for releasing the waveguide once the phototherapy is completed; focusing means formed within the receptacle for receiving the beam of radiation and focusing the radiation on a path into an end surface of the waveguide; and shielding means disposed along said beam path for shielding a peripheral region of the end surface of the waveguide from damage due to the incidence of the focused radiation.
Claim 16
Dependent Claim
135 words
A coupling device for use in a laser therapy system employing a fiber optic waveguide disposed within a catheter to transmit a beam of radiation from said laser therapy system to a patient, the coupling device comprising: a receptacle hermetically sealed to the laser system having an opening adapted to receive the waveguide; fastening means for releasably fastening the waveguide in a precise position in the receptacle during use and for releasing the waveguide once the phototherapy is completed; focusing means formed within the receptacle for receiving the beam of radiation and focusing the radiation on a path into an end surface of the waveguide; and shielding means disposed along said beam path for shielding a peripheral region of the end surface of the waveguide from damage due to the incidence of the focused radiation.
Claim 17
Independent Claim
126 words
A method of performing angioplasty, the method comprising: coupling one end of a fiber optic waveguide carried within a catheter to a tunable source of radiation, said source producing a pulsed beam of radiation tunable over at least a portion of a spectrum ranging from about 300 to about 1000 nanometers and having a peak energy density ranging from about 0.2 Joules per square centimeter to about 20 Joules per square centimeter; disposing the catheter and waveguide within a blood vessel and locating the other end of the waveguide adjacent to an obstruction within the vessel; irradiating the obstruction to remove it by photodecomposition while varying the output of the radiation source within predefined ranges of energy and wavelength in response to conditions encountered during angioplasty.
Claim 18
Independent Claim
126 words
A method of performing angioplasty, the method comprising: coupling one end of a fiber optic waveguide carried within a catheter to a tunable source of radiation, said source producing a pulsed beam of radiation tunable over at least a portion of a spectrum ranging from about 300 to about 1000 nanometers and having a peak energy density ranging from about 0.2 Joules per square centimeter to about 20 Joules per square centimeter; disposing the catheter and waveguide within a blood vessel and locating the other end of the waveguide adjacent to an obstruction within the vessel; irradiating the obstruction to remove it by photodecomposition while varying the output of the radiation source within predefined ranges of energy and wavelength in response to conditions encountered during angioplasty.
Claim 19
Dependent Claim
27 words
The method of claim 15 wherein the step of irradiating the obstruction further includes irradiating with a radiation beam having a wavelength greater than about 307 nanometers.
Claim 20
Dependent Claim
41 words
The method of claim 15 wherein the step of disposing the catheter and waveguide within the blood vessel further includes positioning the waveguide by viewing the internal surface of the blood vessel through an optical system also disposed within the catheter.
Claim 21
Dependent Claim
41 words
The method of claim 15 wherein the step of disposing the catheter and waveguide within the blood vessel further includes positioning the waveguide by viewing the internal surface of the blood vessel through an imaging device also disposed within the catheter.
Claim 22
Dependent Claim
35 words
The method of claim 15 wherein the step of disposing the catheter within the blood vessel further comprises employing an inflation means to obstruct blood flow in front of said other end of the waveguide.
Claim 23
Dependent Claim
22 words
The method of claim 15 wherein the method further comprises removing any debris from the irradiated obstruction by evacuation through the catheter.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-09-04 | 1993-03-06 | 1993-09-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-09-04 | 1997-03-06 | 1997-09-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-09-04 | 2001-03-06 | 2001-09-05 | $7700.00 | Window Closed / Lapsed |