US20030153971A1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Metal reinforced biodegradable intraluminal stents
Assignee: Boston Scientific Scimed Inc
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Filing: 2002-02-14
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Granted: —
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Expires: 2022-02-14
Abstract
Abstract The present invention provides an intraluminal stent comprising a metallic reinforcing component and a biodegradable polymeric material covering at least a portion of the metallic reinforcing component. The metallic reinforcing component provides structural reinforcement for the stent, but this reinforcement is insufficient, in the absence of the biodegradable polymeric material, to provide a stent capable of maintaining patency of a lumen upon implantation of the stent into the lumen. One advantage of the present invention, among others, is that a stent is provided in which reduced amounts of metallic component remain after degradation of the biodegradable polymeric material covering, in turn reducing the incidence of metal-associated adverse events that frequently follow implantation.
Inventors
- 👤 Chandru Chandrasekaran
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:42
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61F2/07; A61L; A61L31/00; A61L31/02; A61L31/022; A61L31/08; A61L31/10; A61F2/82; A61F2/86; A61F2/90; A61F2002/072
Claims Analysis
Total Claims: 28
Claim 1
Independent Claim
65 words
1 . An intraluminal stent comprising: a metallic reinforcing component; and a biodegradable polymeric material covering at least a portion of the metallic reinforcing component; the metallic reinforcing component providing structural reinforcement for the stent but being insufficient, in the absence of the biodegradable polymeric material, to provide a stent capable of maintaining patency of a lumen upon implantation of the stent into the lumen.
Claim 2
Dependent Claim
65 words
1 . An intraluminal stent comprising: a metallic reinforcing component; and a biodegradable polymeric material covering at least a portion of the metallic reinforcing component; the metallic reinforcing component providing structural reinforcement for the stent but being insufficient, in the absence of the biodegradable polymeric material, to provide a stent capable of maintaining patency of a lumen upon implantation of the stent into the lumen.
Claim 3
Dependent Claim
37 words
2 . The intraluminal stent of claim 1 , wherein the metallic reinforcing component comprises a biocompatible metal selected from the group consisting of stainless steel, titanium alloys, tantalum alloys, nickel alloys, cobalt alloys and precious metals.
Claim 4
Dependent Claim
18 words
3 . The intraluminal stent of claim 2 , wherein the biocompatible metal comprises a shape memory alloy.
Claim 5
Dependent Claim
18 words
4 . The intraluminal stent of claim 3 , wherein the shape memory alloy comprises a nickel-titanium alloy.
Claim 6
Dependent Claim
42 words
5 . The intraluminal stent of claim 1 , wherein the biodegradable polymeric material comprises a biocompatible biodegradable polymer selected from the group consisting of polylactic acid, polyglycolic acid, polycaprolactone, polyorthoesters, and trimethylene carbonate polymers, as well as copolymers and mixtures thereof.
Claim 7
Dependent Claim
28 words
6 . The intraluminal stent of claim 1 , wherein the stent is selected from the group consisting of endovascular, biliary, tracheal, gastrointestinal, urethral, ureteral and esophageal stents.
Claim 8
Dependent Claim
16 words
7 . The intraluminal stent of claim 6 , wherein the stent is balloon-expandable or self-expandable.
Claim 9
Dependent Claim
17 words
8 . The intraluminal stent of claim 6 , wherein the endovascular stent is a coronary stent.
Claim 10
Dependent Claim
19 words
9 . The intraluminal stent of claim 1 , wherein the metallic reinforcing component comprises a plurality of apertures.
Claim 11
Dependent Claim
57 words
10 . The intraluminal stent of claim 9 , wherein the metallic reinforcing component is selected from the group consisting of an open-mesh network comprising one or more knitted, woven or braided metallic filaments; an interconnected network of articulable segments; a coiled or helical structure comprising one or more metallic filaments; and, a patterned tubular metallic sheet.
Claim 12
Dependent Claim
19 words
11 . The intraluminal stent of claim 10 , wherein said metallic filaments comprise two or more different metals.
Claim 13
Dependent Claim
27 words
12 . The intraluminal stent of claim 10 , wherein the patterned tubular metallic sheet is formed by laser cutting or chemical etching of a metallic sheet.
Claim 14
Dependent Claim
31 words
13 . The intraluminal stent of claim 9 , wherein the biodegradable polymeric material covering at least a portion of the metallic reinforcing component comprises a biodegradable polymeric material coating layer.
Claim 15
Dependent Claim
24 words
14 . The intraluminal stent of claim 13 , wherein said biodegradable polymeric material coating layer comprises one or more therapeutic and/or diagnostic agents.
Claim 16
Dependent Claim
33 words
15 . The intraluminal stent of claim 9 , wherein the biodegradable polymeric material covering at least a portion of the metallic reinforcing component comprises two or more biodegradable polymeric material coating layers.
Claim 17
Dependent Claim
28 words
16 . The intraluminal stent of claim 15 , wherein one or more of the biodegradable polymeric material coating layers comprise one or more therapeutic and/or diagnostic agents.
Claim 18
Dependent Claim
31 words
17 . The intraluminal stent of claim 16 , wherein different therapeutic agents or combinations of therapeutic agents are present in two of more of said biodegradable polymeric material coating layers.
Claim 19
Dependent Claim
25 words
18 . The intraluminal stent of claim 15 , wherein at least two of said biodegradable polymeric material coating layers have different rates of biodegradation.
Claim 20
Dependent Claim
29 words
19 . The intraluminal stent of claim 16 , wherein at least two of said biodegradable polymeric material coating layers have different rates of release of therapeutic agent therefrom.
Claim 21
Dependent Claim
24 words
20 . The intraluminal stent of claim 9 , wherein the metallic reinforcing component and biodegradable polymeric material are provided within a laminated structure.
Claim 22
Dependent Claim
26 words
21 . The intraluminal stent of claim 20 , wherein the metallic reinforcing component is disposed between two or more layers of the biodegradable polymeric material.
Claim 23
Dependent Claim
20 words
22 . The intraluminal stent of claim 21 , wherein the two or more layers comprise different biodegradable polymeric materials.
Claim 24
Dependent Claim
27 words
23 . The intraluminal stent of claim 21 , wherein at least one of said two or more layers comprises one or more therapeutic and/or diagnostic agents.
Claim 25
Dependent Claim
27 words
24 . The intraluminal stent of claim 23 , wherein different therapeutic agents or combinations of therapeutic agents are present in two or more of said layers.
Claim 26
Dependent Claim
21 words
25 . The intraluminal stent of claim 21 , wherein at least two of said layers have different rates of biodegradation.
Claim 27
Dependent Claim
25 words
26 . The intraluminal stent of claim 23 , wherein at least two of said layers have different rates of release of therapeutic agent therefrom.
Claim 28
Dependent Claim
23 words
27 . The intraluminal stent of claim 1 , wherein a surface of the metallic reinforcing component is passivated to enhance its biocompatibility.
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