US6139510A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Super elastic alloy guidewire
Assignee: Target Therapeutics Inc
•
Filing: 1994-05-11
•
Granted: 2000-10-31
•
Expires: 2014-05-11
Abstract
Abstract This invention is a surgical device. It is a guidewire for use in a catheter and is used for accessing a targeted site in a lumen system of a patient's body. The guidewire may be of a high elasticity metal alloy, preferably a Ni-Ti alloy, having specified physical parameters, and is especially useful for accessing peripheral or soft tissue targets. A special variation of the inventive guidewire includes the concept of coating the wire with a one or more lubricious polymers to enhance its suitability for use within catheters and with the interior of vascular lumen. The "necked" guidewire tip also forms a specific variant of the invention.
Inventors
- 👤 Thomas J. Palermo
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 15:19
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/01; A61M25/09; A61L; A61L31/00; A61L31/02; A61L31/022; A61L31/08; A61L31/10; A61L2400/00; A61L2400/16; A61M2025/09133; A61M2025/09141; A61M2025/09175; A61M25/09016; A61M25/09033
Claims Analysis
Total Claims: 45
Claim 1
Independent Claim
85 words
A guidewire suitable for guiding a catheter within a body lumen, comprising an elongated, flexible metal wire core of a super-elastic alloy having a UP of 75 ksi±10 ksi, an LP of 25 ksi±7.5 ksi measured at 3% strain and a RS of less than 0.25% where measured in a stress-strain test to 6% strain, in which at least a portion of the guidewire is coated with a polymeric material and additionally comprising a tie layer disposed between the polymeric layer and the guidewire core.
Claim 2
Dependent Claim
85 words
A guidewire suitable for guiding a catheter within a body lumen, comprising an elongated, flexible metal wire core of a super-elastic alloy having a UP of 75 ksi±10 ksi, an LP of 25 ksi±7.5 ksi measured at 3% strain and a RS of less than 0.25% where measured in a stress-strain test to 6% strain, in which at least a portion of the guidewire is coated with a polymeric material and additionally comprising a tie layer disposed between the polymeric layer and the guidewire core.
Claim 3
Dependent Claim
16 words
The guidewire of claim 1, where the guidewire has a eccentricity ratio of 1±10 -4 .
Claim 4
Dependent Claim
16 words
The guidewire of claim 1, having a distal section, a middle section, and a proximal section.
Claim 5
Dependent Claim
12 words
The guidewire of claim 1, in which the super-elastic alloy is Ni-Ti.
Claim 6
Dependent Claim
15 words
The guidewire of claim 3, in which the distal section is tapered to a point.
Claim 7
Dependent Claim
16 words
The guidewire of claim 5, in which the distal section is coated with a malleable metal.
Claim 8
Dependent Claim
25 words
The guidewire of claim 6, in which the malleable metal is selected from the group consisting of gold, nickel, silver, platinum, palladium and alloys thereof.
Claim 9
Dependent Claim
34 words
The guidewire of claim 6, in which the at least a portion of the malleable metal coating on the distal portion is covered by an outer coil comprising platinum, tungsten, or an alloy thereof.
Claim 10
Dependent Claim
21 words
The guidewire of claim 4, in which the distal section comprises a proximal tapered portion and a constant diameter distal portion.
Claim 11
Dependent Claim
16 words
The guidewire of claim 9, in which the distal section is coated with a malleable metal.
Claim 12
Dependent Claim
24 words
The guidewire of claim 10, in which the malleable metal is selected from the group consisting of gold, silver, platinum, palladium and alloys thereof.
Claim 13
Dependent Claim
34 words
The guidewire of claim 11, in which the at least a portion of the malleable metal coating on the distal portion is covered by an outer coil comprising platinum, tungsten, or an alloy thereof.
Claim 14
Dependent Claim
15 words
The guidewire of claim 11, wherein an inner coil surrounds the constant diameter distal portion.
Claim 15
Dependent Claim
27 words
The guidewire of claim 13, wherein the inner coil comprises a radiopaque metal selected from the group consisting of platinum, tungsten, or an alloy of the two.
Claim 16
Dependent Claim
23 words
The guidewire of claim 14, wherein a metallic ribbon secures the wire core to the inner coil and further to the outer coil.
Claim 17
Dependent Claim
23 words
The guidewire of claim 4, in which the distal section comprises a necked down portion of smaller diameter than its surrounding distal section.
Claim 18
Dependent Claim
26 words
The guidewire of claim 16, in which at least a portion of the necked down section of the distal portion is covered by an outer coil.
Claim 19
Dependent Claim
29 words
The guidewire of claim 4, in which the outer coil is connected at its distal end by a ribbon joined to the necked down section of the distal portion.
Claim 20
Dependent Claim
25 words
The guidewire of claim 18, in where an inner coil is secured between the ribbon and the necked down section all within the outer coil.
Claim 21
Dependent Claim
96 words
The guidewire of claim 1 where the polymeric material comprises polymers produced from monomers selected from ethylene oxide; 2-vinyl pyridine; N-vinylpyrrolidone; polyethylene glycol acrylates such as mono-alkoxy polyethylene glycol mono(meth) acrylates, including mono-methoxy triethylene glycol mono (meth) acrylate, mono-methoxy tetraethylene glycol mono (meth) acrylate, polyethylene glycol mono (meth) acrylate; other hydrophilic acrylates such as 2-hydroxyethylmethacrylate, glycerylmethacrylate; acrylic acid and its salts; acrylamide and acrylonitrile; acrylamidomethylpropane sulfonic acid and its salts, cellulose, cellulose derivatives such as methyl cellulose ethyl cellulose, carboxymethyl cellulose, cyanoethyl cellulose, cellulose acetate, polysaccharides such as amylose, pectin, amylopectin, alginic acid, and cross-linked heparin.
Claim 22
Dependent Claim
23 words
The guidewire of claim 1, where the tie layer disposed between the polymeric layer and the guidewire core is a heat shrunk tubing.
Claim 23
Dependent Claim
32 words
The guidewire of claim 21, where the tie layer disposed between the polymeric layer and the guidewire core is a heat shrunk tubing comprising a material selected from polyethylene terephthalate and polyurethane.
Claim 24
Dependent Claim
29 words
The guidewire of claim 21, where the tie layer disposed between the polymeric layer and the guidewire core is a heat shrunk tubing and further comprises a radiopaque material.
Claim 25
Dependent Claim
22 words
The guidewire of claim 1, where the tie layer disposed between the polymeric layer and the guidewire core is deposited by plasma.
Claim 26
Dependent Claim
10 words
The guidewire of claim 1 additionally comprising a catheter sheath.
Claim 27
Dependent Claim
85 words
A guidewire suitable for guiding a catheter within a blood vessel, comprising an elongated flexible metal wire core having a distal section including a necked down portion having a diameter smaller than a linearly contiguous section just distal of the necked down portion; an outer coil surrounding at least a portion of the distal section, such portion of the distal section comprising at least the smaller diameter portion; and a metallic ribbon securing the outer coil to the smaller diameter portion of the distal section.
Claim 28
Dependent Claim
85 words
A guidewire suitable for guiding a catheter within a blood vessel, comprising an elongated flexible metal wire core having a distal section including a necked down portion having a diameter smaller than a linearly contiguous section just distal of the necked down portion; an outer coil surrounding at least a portion of the distal section, such portion of the distal section comprising at least the smaller diameter portion; and a metallic ribbon securing the outer coil to the smaller diameter portion of the distal section.
Claim 29
Dependent Claim
20 words
The guidewire of claim 26, wherein an inner coil is located within the smaller diameter portion of the distal section.
Claim 30
Dependent Claim
29 words
The guidewire of claim 26, wherein the wire core comprises a material selected from the group consisting of high elasticity alloys, stainless steel, platinum, palladium, rhodium and alloys thereof.
Claim 31
Dependent Claim
12 words
The guidewire of claim 28, where the material is a Ni-Ti alloy.
Claim 32
Dependent Claim
27 words
The guidewire of claim 26, wherein the outer coil comprises a radiopaque material selected from the group consisting of platinum, tungsten, or an alloy of the two.
Claim 33
Dependent Claim
27 words
The guidewire of claim 26, wherein the inner coil comprises a radiopaque material selected from the group consisting of platinum, tungsten or an alloy of the two.
Claim 34
Dependent Claim
86 words
A guidewire suitable for guiding a catheter within a blood vessel, comprising an elongated flexible metal wire core of a super-elastic alloy having a tie layer disposed about at least a portion of the core, where said tie layer has been shrunk onto the wire core, where said tie layer comprises at least one of NYLON, polyethylene, polystyrene, polyurethane and polyethylene terephthalate, and where said tie layer further comprises one or more radio opaque material selected from barium sulfate, bismuth trioxide, bismuth carbonate, tungsten and tantalum.
Claim 35
Dependent Claim
86 words
A guidewire suitable for guiding a catheter within a blood vessel, comprising an elongated flexible metal wire core of a super-elastic alloy having a tie layer disposed about at least a portion of the core, where said tie layer has been shrunk onto the wire core, where said tie layer comprises at least one of NYLON, polyethylene, polystyrene, polyurethane and polyethylene terephthalate, and where said tie layer further comprises one or more radio opaque material selected from barium sulfate, bismuth trioxide, bismuth carbonate, tungsten and tantalum.
Claim 36
Dependent Claim
14 words
The guidewire of claim 32, where the super-elastic alloy material is a Ni-Ti alloy.
Claim 37
Dependent Claim
21 words
The guidewire of claim 33, where the tie layer comprises at least one of NYLON, polyethylene, polystyrene, polyurethane, and polyethylene terephthalate.
Claim 38
Dependent Claim
14 words
The guidewire of claim 34, where the tie layer comprises polyethylene terephthalate or polyurethane.
Claim 39
Dependent Claim
28 words
The guidewire of claim 34, where the tie layer further comprises one or more radio opaque materials selected from barium sulfate, bismuth trioxide, bismuth carbonate, tungsten, and tantalum.
Claim 40
Dependent Claim
101 words
The guidewire of claim 32, additionally comprising a layer disposed about the tie layer comprising polymers produced from monomers selected from ethylene oxide; 2-vinyl pyridine; N-vinylpyrrolidone; polyethylene glycol acrylates such as mono-alkoxy polyethylene glycol mono(meth) acrylates, including mono-methoxy triethylene glycol mono (meth) acrylate, mono-methoxy tetraethylene glycol mono (meth) acrylate, polyethylene glycol mono (meth) acrylate; other hydrophilic acrylates such as 2-hydroxyethylmethacrylate, glycerylmethacrylate; acrylic acid and its salts; acrylamide and acrylonitrile; acrylamidomethylpropane sulfonic acid and its salts, cellulose, cellulose derivatives such as methyl cellulose ethyl cellulose, carboxymethyl cellulose, cyanoethyl cellulose, cellulose acetate, polysaccharides such as amylose, pectin, amylopectin, alginic acid, and cross-linked heparin.
Claim 41
Dependent Claim
31 words
The guidewire of claim 26, wherein said section just distal of the necked down portion is substantially flattened and has a width greater than said diameter of said necked down portion.
Claim 42
Dependent Claim
14 words
The guidewire of claim 32, where said tie layer comprises polyethylene terephthalate or polyurethane.
Claim 43
Dependent Claim
145 words
A guidewire suitable for guiding a catheter within a blood vessel, comprising an elongated flexible metal wire core of a super-elastic alloy having a tie layer disposed about at least a portion of the core, where said tie layer has been shrunk onto the wire core, and a layer disposed about said tie layer, said layer disposed about said tie layer comprising polymers produced from monomers selected from ethylene oxide; 2-vinyl pyridine; N-vinylpyrrolidone; polyethylene glycol acrylates such as mon-alkoxy polyethylene glycol mono(meth) acrylates, including mono-methoxy triethylene glycol mono(meth) acrylate, mono-methoxy tetraethylene glyco mono(meth) acrylate, polyethylene glycol mono(meth) acrylate; other hydrophilic acrylates such as 2-hydroxyethylmethacrylate, glycerylmethacrylate; acrylic acid and its salts; acrylamide and acrylonitrile; acrylamidomethylpropane sulfonic acid and its salts; cellulose; cellulose derivatives such as methyl cellulose, ethyl cellulose, carboxymethyl cellulose, cyanoethyl cellulose, cellulose acetate; polysaccharides such as amylose, pectin, amylopectin, alginic acid, and cross-linked heparin.
Claim 44
Dependent Claim
145 words
A guidewire suitable for guiding a catheter within a blood vessel, comprising an elongated flexible metal wire core of a super-elastic alloy having a tie layer disposed about at least a portion of the core, where said tie layer has been shrunk onto the wire core, and a layer disposed about said tie layer, said layer disposed about said tie layer comprising polymers produced from monomers selected from ethylene oxide; 2-vinyl pyridine; N-vinylpyrrolidone; polyethylene glycol acrylates such as mon-alkoxy polyethylene glycol mono(meth) acrylates, including mono-methoxy triethylene glycol mono(meth) acrylate, mono-methoxy tetraethylene glyco mono(meth) acrylate, polyethylene glycol mono(meth) acrylate; other hydrophilic acrylates such as 2-hydroxyethylmethacrylate, glycerylmethacrylate; acrylic acid and its salts; acrylamide and acrylonitrile; acrylamidomethylpropane sulfonic acid and its salts; cellulose; cellulose derivatives such as methyl cellulose, ethyl cellulose, carboxymethyl cellulose, cyanoethyl cellulose, cellulose acetate; polysaccharides such as amylose, pectin, amylopectin, alginic acid, and cross-linked heparin.
Claim 45
Dependent Claim
14 words
The guidewire of claim 32, where the super-elastic alloy material is a Ni-Ti alloy.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-10-31 | 2004-05-01 | 2004-10-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-10-31 | 2008-05-01 | 2008-10-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-10-31 | 2012-05-01 | 2012-10-31 | $7700.00 | Window Closed / Lapsed |