Patent EP0350104A2 successfully refreshed from Google Patents.
Patent EP0262384A1 successfully refreshed from Google Patents.
EP0262384A1
Expired / Lapsed
EP
⏱️ 0.0 years remaining
23-Deoxy derivatives of LL-F28249 Compounds
Assignee: Wyeth Holdings LLC
•
Filing: 1987-08-25
•
Granted: —
•
Expires: 2007-08-25
Abstract
Abstract The present invention relates to novel derivatives of LL-F28249 compounds. These LL-F28249 compounds preferably are derived via a controlled microbiological fermentation of Streptomyces cyaneogriseus subsp. noncyanogenus having deposit accession number NRRL 15773. The 23-deoxy derivatives have the 23-hydroxy group replaced by hydrogen. The novel derivatives of the present invention possess activity as anthelmintic, ectoparasitic, insecticidal, acaricidal and nematicidal agents. They also are useful in areas of human and animal health and in agricultural crops.
Inventors
- 👤 Goro Asato
- 👤 Susan Yoshiko Tamura
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-04 12:43
CPC Classifications
C; C07; C07D; C07D493/00; C07D493/22; C07H; C07H19/00; C07H19/01; A; A01; A01N; A01N43/00; A01N43/90; A01N49/00; A23; A23K; A23K20/00; A23K20/10; A23K20/195; A61; A61P; A61P11/00; A61P11/16
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
38 words
The compounds characterized by structural formula (I), wherein R₁ is methyl, ethyl or isopropyl; R₂ is hydrogen or methyl; R₃ is hydrogen, methyl or ethyl; R₄ is methyl or ethyl; and the pharmaceutically and pharmacologically acceptable salts thereof.
Claim 2
Dependent Claim
38 words
The compounds characterized by structural formula (I), wherein R₁ is methyl, ethyl or isopropyl; R₂ is hydrogen or methyl; R₃ is hydrogen, methyl or ethyl; R₄ is methyl or ethyl; and the pharmaceutically and pharmacologically acceptable salts thereof.
Claim 3
Dependent Claim
37 words
A compound according to Claim 1, wherein R₁ is isopropyl; R₂ is hydrogen or methyl; R₃ is methyl; and R₄ is methyl; and wherein R₁ is isopropyl; R₂ is hydrogen; R₃ is methyl; and R₄ is methyl.
Claim 4
Independent Claim
71 words
A method for the prevention, treatment or control of parasitic infections in warm-blooded animals, said method characterized by: orally, topically or parenterally administering to an animal infected with parasites, a parasiticidally-effective amount of the compounds represented by structural formula (I) wherein R₁ is methyl, ethyl or isopropyl; R₂ is hydrogen or methyl; R₃ is hydrogen, methyl or ethyl; R₄ is methyl or ethyl; and the pharmaceutically and pharmacologically acceptable salts thereof.
Claim 5
Independent Claim
71 words
A method for the prevention, treatment or control of parasitic infections in warm-blooded animals, said method characterized by: orally, topically or parenterally administering to an animal infected with parasites, a parasiticidally-effective amount of the compounds represented by structural formula (I) wherein R₁ is methyl, ethyl or isopropyl; R₂ is hydrogen or methyl; R₃ is hydrogen, methyl or ethyl; R₄ is methyl or ethyl; and the pharmaceutically and pharmacologically acceptable salts thereof.
Claim 6
Dependent Claim
43 words
A method according to Claim 3, wherein said compound has R₁ as isopropyl; R₂ is hydrogen or methyl; R₃ is methyl; and R₄ as methyl; and wherein said compound has R₁ as isopropyl; R₂ is hydrogen; R₃ is methyl; and R₄ is methyl.
Claim 7
Independent Claim
66 words
A method for controlling plant insects, topically or systemically, and protecting crops, trees, shrubs, stored grain and ornamentals, said method characterized by: applying an insecticidally-effective amount of the compound represented by the structural formula (I) wherein R₁ is methyl, ethyl or sopropyl; R₂ is hydrogen or methyl; R₃ is hydrogen, methyl or ethyl; R₄ is methyl or ethyl; and the pharmaceutically and pharmacologically acceptable salts thereof.
Claim 8
Independent Claim
66 words
A method for controlling plant insects, topically or systemically, and protecting crops, trees, shrubs, stored grain and ornamentals, said method characterized by: applying an insecticidally-effective amount of the compound represented by the structural formula (I) wherein R₁ is methyl, ethyl or sopropyl; R₂ is hydrogen or methyl; R₃ is hydrogen, methyl or ethyl; R₄ is methyl or ethyl; and the pharmaceutically and pharmacologically acceptable salts thereof.
Claim 9
Dependent Claim
29 words
A method according to Claim 5, wherein said compound is applied to the foliage of crops and plants, the soil in which they are grown or the trunk thereof.
Claim 10
Dependent Claim
43 words
A method according to Claim 6, wherein said compound has R₁ as isopropyl; R₂ is hydrogen or methyl; R₃ is methyl; and R₄ is methyl; and wherein said compound is R₁ as isopropyl; R₂ is hydrogen; R₃ is methyl; and R₄ is methyl.
Claim 11
Independent Claim
72 words
A method for the control of plant nematodes, said method characterized by: applying to the foliage of plants, the soil in which they are grown or into the trunks thereof, a nematocidally-effective amount of the compound represented by structural formula (I), wherein R₁ is methyl, ethyl or isopropyl; R₂ is hydrogen or methyl; R₃ is hydrogen, methyl or ethyl; R₄ is methyl or ethyl; and the pharmaceutically and pharmacologically acceptable salts thereof.
Claim 12
Independent Claim
72 words
A method for the control of plant nematodes, said method characterized by: applying to the foliage of plants, the soil in which they are grown or into the trunks thereof, a nematocidally-effective amount of the compound represented by structural formula (I), wherein R₁ is methyl, ethyl or isopropyl; R₂ is hydrogen or methyl; R₃ is hydrogen, methyl or ethyl; R₄ is methyl or ethyl; and the pharmaceutically and pharmacologically acceptable salts thereof.
Claim 13
Dependent Claim
43 words
A method according to Claim 8, wherein said compound has R₁ as isopropyl; R₂ is hydrogen or methyl; R₃ is methyl; and R₄ is methyl; and wherein said compound has R₁ as isopropyl; R₂ is hydrogen; R₃ is methyl; and R₄ is methyl.
Claim 14
Dependent Claim
67 words
A composition for the treatment, prevention or control of parasitic infections in warm-blooded animals, said composition characterized by: a prophylactically, therapeutically or pharmaceutically-effective amount of the compound represented by structural formula (I), wherein R₁ is methyl, ethyl or isopropyl; R₂ is hydrogen or methyl; R₃ is hydrogen, methyl or ethyl; R₄ is methyl or ethyl; or the pharmaceutically and pharmacologically acceptable salts thereof; and an inert carrier.
Claim 15
Dependent Claim
67 words
A composition for the treatment, prevention or control of parasitic infections in warm-blooded animals, said composition characterized by: a prophylactically, therapeutically or pharmaceutically-effective amount of the compound represented by structural formula (I), wherein R₁ is methyl, ethyl or isopropyl; R₂ is hydrogen or methyl; R₃ is hydrogen, methyl or ethyl; R₄ is methyl or ethyl; or the pharmaceutically and pharmacologically acceptable salts thereof; and an inert carrier.
Claim 16
Dependent Claim
56 words
A composition for controlling plant insects, said composition characterized by: an insecticidally-effective amount of the compound represented by structural formula (I), wherein R₁ is methyl, ethyl or isopropyl; R₂ is hydrogen or methyl; R₃ is hydrogen, methyl or ethyl; R₄ is methyl or ethyl; or the pharmaceutically and pharmacologically acceptable salts thereof; and an inert carrier.
Claim 17
Dependent Claim
56 words
A composition for controlling plant insects, said composition characterized by: an insecticidally-effective amount of the compound represented by structural formula (I), wherein R₁ is methyl, ethyl or isopropyl; R₂ is hydrogen or methyl; R₃ is hydrogen, methyl or ethyl; R₄ is methyl or ethyl; or the pharmaceutically and pharmacologically acceptable salts thereof; and an inert carrier.
References Cited (Backward Citations)
US3950360A
Cited
EP0002615A2
Cited
EP0170006A2
Cited
FR2570390A1
Cited
EP0214731A2
Cited
EP0215654A2
Cited
USPTO Annuity & Maintenance Windows
Maintenance schedule is calculated for granted US utility patents.