Patent EP0000949A1 successfully refreshed from Google Patents.
EP0000949A1
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EP
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Cardiac and vascular prostheses and methods of making the same
Assignee: Individual
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Filing: 1978-08-25
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Granted: —
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Expires: 1998-08-25
Abstract
Abstract Cardiac and vascular prostheses and methods of making the same. The prostheses are suitable for implantation in a bloody environment. The prosthesis includes a surface material adapted for exhibiting a regular and periodic surface charge characteristic in the bloody environment (See Fig. 1A: scanning electron micrographs of an albumin Dacron hybrid graft). A prothesis means supports the surface material and is adapted to perform a prosthetic function in the bloody environment. In cases where cross- linking is desired and the surface material cannot cross-link with the substrate material, an adaptive material is provided which cross-links both to the surface material and to the material of the prothesis.
Inventors
- 👤 Philip Nicholas Sawyer
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 18:32
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/0077; A61L; A61L27/00; A61L27/14; A61L27/28; A61L27/34; A61L27/50; A61L27/507; A61L33/00
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
51 words
A prosthesis suitable for implantation in a bloody environment, particularly for cardiac and vascular implants, said prosthesis comprising a surface material adapted for exhibiting a regular and periodic surface charge characteristic in said environment, and prosthesis means supporting said surface material and adapted to perform a prosthetic function in said environment.
Claim 2
Dependent Claim
51 words
A prosthesis suitable for implantation in a bloody environment, particularly for cardiac and vascular implants, said prosthesis comprising a surface material adapted for exhibiting a regular and periodic surface charge characteristic in said environment, and prosthesis means supporting said surface material and adapted to perform a prosthetic function in said environment.
Claim 3
Dependent Claim
53 words
A prosthesis as claimed in claim 1, wherein said prosthesis means is of a material normally incapable of cross- linking to said surface material, comprising an adaptive material to cross-link to the material of said prosthesis means and to said surface material to provide architectural continuity therebetween while preserving said surface charge characteristic.
Claim 4
Dependent Claim
18 words
A prosthesis as claimed in claim 2, wherein said adaptive material is glutaraldehyde or a succinic acid compound.
Claim 5
Dependent Claim
26 words
A prosthesis as claimed in claim 2, wherein said surface charge is equivalent to approximately one electron per thousand square Angstroms in a regular three-dimensional pattern.
Claim 6
Dependent Claim
22 words
A prosthesis as claimed in any of claims 1 to 4, wherein said surface material is aluminum, a protein, agar or acrylamide.
Claim 7
Dependent Claim
17 words
A prosthesis as claimed in claim 5, wherein said pro- . tein is albumin, gelatin or collagen.
Claim 8
Dependent Claim
16 words
A prosthesis as claimed in claim 5, wherein said surface material is albumin combined with gelatin.
Claim 9
Dependent Claim
18 words
A prosthesis as claimed in any of claims 1 to 7, wherein said prosthesis means is of Dacron.
Claim 10
Dependent Claim
15 words
A prosthesis as claimed in claim 8, wherein said Dacron is of a woven structure.
Claim 11
Independent Claim
40 words
A method of preparing a prosthesis for functioning in a bloody environment with minimal thrombogenicity said method comprising depositing on the surface of the prosthesis means a material adapted for exhibiting a regular and periodic suface charge in said environment.
Claim 12
Independent Claim
40 words
A method of preparing a prosthesis for functioning in a bloody environment with minimal thrombogenicity said method comprising depositing on the surface of the prosthesis means a material adapted for exhibiting a regular and periodic suface charge in said environment.
Claim 13
Dependent Claim
33 words
A method as claimed in claim 10, wherein said surface material is normally incapable of cross-linking to said prosthesis means comprising cross-linking the said material to said prosthesis means with an adaptive material.
Claim 14
Dependent Claim
18 words
A method as claimed in claim 11, wherein said adaptive material is glutaraldehyde or a succinic acid compound.
Claim 15
Independent Claim
23 words
A method as claimed in any of claims 10, 11 or 12, wherein said surface material is aluminum, a protein, agar or acrylamide.
Claim 16
Dependent Claim
15 words
A method as claimed in claim 13, wherein said protein is albumin, gelatin or collagen.
Claim 17
Dependent Claim
17 words
A method as claimed in claim 13, wherein the said surface material is albumin combined with gelatin.
Claim 18
Dependent Claim
22 words
A method as claimed in claim 13, wherein said surface material is a protein and is applied in about 3 % solution.
Claim 19
Independent Claim
30 words
A method of adapting a synthetic material for use as a prosthetic material adapted to function in a bloody environment, said method comprising metallizing the material at the surface thereof.
Claim 20
Independent Claim
30 words
A method of adapting a synthetic material for use as a prosthetic material adapted to function in a bloody environment, said method comprising metallizing the material at the surface thereof.
Claim 21
Independent Claim
17 words
A method as claimed in claims 13 or 17, comprising vapor depositing aluminum on said prosthesis means.
Claim 22
Independent Claim
19 words
A method as claimed in claims 13 or 17, comprising spraying aluminum in an aerosol on said prosthesis means.
Claim 23
Independent Claim
19 words
A method as claimed in any of claims 10 to 19, wherein the prosthesis means is of woven Dacron.
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