Patent US3646939A successfully refreshed from Google Patents.
US3914802A
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Non-thrombogenic prosthetic material
Assignee: Individual
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Filing: 1974-05-23
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Granted: 1975-10-28
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Expires: 1994-05-23
Abstract
Abstract A non-thrombogenic material possessing mechanical, chemical, biological and electrical properties that render the material acceptable for a broad range of prosthetic applications. The material is provided with a hydrophilic inner lining formed primarily of a sintered network of colloidal silica bonded onto a thin layer of oxygen-diffusing elastomeric material, reinforced by a porous fabric backing. The silica imparts a net negative charge to the lining which repels negatively-charged blood platelets in contact therewith. The silica network acts as a matrix to promote the growth of neo-intima.
Inventors
- 👤 Franklin G Reick
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:06
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61L; A61L33/00; A61L33/02; A61L33/027; Y; Y10; Y10S; Y10S128/00; Y10S128/21
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
81 words
A NON-THROMBOGENIC PROSTHETIC MATERIAL COMPRISING: A. AN ELASTROMERIC LAYER CAPABLE OF OXYGEN-DIFFUSION, THE OUTER FACE OF THE LAYER BEING BONDED TO A FABRIC BACKING ACTING TO REINFORCE THE LAYER, THE INTERSTICS OF THE FABRIC PERMITTING CELLULAR DIFFUSION TO LOCK THE MATERIAL IN PLACE AFTER IMPLANTATION, AND B. A LINING BONDED TO THE INNER FACE OF SAID LAYER AND FORMED PRIMARY OF COLLOIDAL, NEGATIVELY-CHARGED SILICA PARTICLES TO REPEL NEGATIVELY-CHARGED BLOOD PLATELETS IN CONTACT THEREWITH, SAID PARTICLES BEING SINTERED TO DEFINE A THREE-
Claim 2
Dependent Claim
81 words
A NON-THROMBOGENIC PROSTHETIC MATERIAL COMPRISING: A. AN ELASTROMERIC LAYER CAPABLE OF OXYGEN-DIFFUSION, THE OUTER FACE OF THE LAYER BEING BONDED TO A FABRIC BACKING ACTING TO REINFORCE THE LAYER, THE INTERSTICS OF THE FABRIC PERMITTING CELLULAR DIFFUSION TO LOCK THE MATERIAL IN PLACE AFTER IMPLANTATION, AND B. A LINING BONDED TO THE INNER FACE OF SAID LAYER AND FORMED PRIMARY OF COLLOIDAL, NEGATIVELY-CHARGED SILICA PARTICLES TO REPEL NEGATIVELY-CHARGED BLOOD PLATELETS IN CONTACT THEREWITH, SAID PARTICLES BEING SINTERED TO DEFINE A THREE-
Claim 3
Dependent Claim
16 words
A prosthetic material as set forth in claim 1, wherein said elastomeric material is silicone rubber.
Claim 4
Dependent Claim
16 words
A prosthetic material as set forth in claim 1, wherein said elastomeric material is urethane rubber.
Claim 5
Dependent Claim
18 words
A prosthetic material as set forth in claim 1, wherein said fabric is formed of woven polyester yarns.
Claim 6
Dependent Claim
17 words
A prosthetic material as set forth in claim 3, wherein said yarns are formed of polyethylene terephthalate.
Claim 7
Dependent Claim
41 words
A prosthetic material as set forth in claim 1, wherein said material is in tubular form and said fabric backing is constituted by a sleeve bonded to a tubular layer of elastomeric material whose inner face has said lining bonded thereto.
Claim 8
Dependent Claim
33 words
A prosthetic material as set forth in claim 1, wherein said lining further includes positively-charged fumed alumina particles in a ratio to said negatively charged particles to provide a desired net negative charge.
Claim 9
Dependent Claim
21 words
A prosthetic material as set forth in claim 1, wherein said lining further includes colloidal graphite to render the lining semi-conductive.
Claim 10
Dependent Claim
24 words
A prosthetic material as set forth in claim 1, wherein said elastomeric layer has a thickness in the range of 0.0005 to 0.005 inches.
Claim 11
Dependent Claim
13 words
A material as set forth in claim 1 wherein said particles are hydrophilic.
Claim 12
Dependent Claim
29 words
A material as set forth in claim 10 further including hydrophobic particles in a ratio relative to said hydrophilic particles to impart a desired wetting characteristic to said material.
References Cited (Backward Citations)
US3609768A
Cited
US3843974A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-10-27 | 1979-04-28 | 1979-10-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-10-27 | 1983-04-28 | 1983-10-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-10-27 | 1987-04-28 | 1987-10-28 | $7700.00 | Window Closed / Lapsed |