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Pharmaceuticals having dotted active ingredients and a method and apparatus for the preparation thereof

Assignee: Boehringer Ingelheim GmbH
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Filing: 1982-10-12
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Granted: 1984-12-11
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Expires: 2002-10-12
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Abstract

Abstract A method for the preparation of pharmaceuticals which comprises using a piezoelectric dosing system to dot liquid, dissolved or suspended active substance onto a pharmaceutical carrier.

Inventors

  • 👤 Gunther Voss
  • 👤 Peter Gruber

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-27 22:09
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/2095; A61J; A61J3/00; B; B41; B41J; B41J3/00; B41J3/407; B41J3/4073; A61J2205/00; A61J2205/20

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 49 words
A method for the preparation of solid pharmaceuticals, which comprises dotting liquid, dissolved or suspended active substance in a specific quantity in the form of discrete droplets of specific volume onto a pharmaceutical carrier granulate in a mold before the pharmaceutical carrier granulate is pressed into tablets or cores.
Claim 2
Independent Claim 49 words
A method for the preparation of solid pharmaceuticals, which comprises dotting liquid, dissolved or suspended active substance in a specific quantity in the form of discrete droplets of specific volume onto a pharmaceutical carrier granulate in a mold before the pharmaceutical carrier granulate is pressed into tablets or cores.
Claim 3
Independent Claim 46 words
A method for the preparation of solid pharmaceuticals, which comprises dotting liquid, dissolved or suspended active substance in a specific quantity in the form of discrete droplets of specific volume onto pharmaceutical carrier in the powder bed of an unsealed capsule in a capsule filling machine.
Claim 4
Independent Claim 46 words
A method for the preparation of solid pharmaceuticals, which comprises dotting liquid, dissolved or suspended active substance in a specific quantity in the form of discrete droplets of specific volume onto pharmaceutical carrier in the powder bed of an unsealed capsule in a capsule filling machine.
Claim 5
Independent Claim 18 words
The method of claims 1, or 2, wherein the dotting is effected by means of piezoelectric dosing systems.
Claim 6
Dependent Claim 46 words
The method of claim 3, wherein a piezoelectric transducer wholly or partly encloses an outlet opening and the dotting is effected in such a way that the release of droplets from a liquid standing under pressure is achieved by the controlled opening of the outlet opening.
Claim 7
Independent Claim 52 words
The method of claims 1, or 2, wherein the liquid, dissolved or suspended active ingredient is broken up under high pressure during passage through a nozzle into discrete droplets of specific volume and the individual droplets are successively charged electrically and intermittently deflected electromagnetically to the desired points of the pharmaceutical carrier.
Claim 8
Independent Claim 118 words
The method of claims 1, or 2, wherein pharmaceutical carriers are dotted in series next to one another with the liquid, dissolved or suspended active substance. .[.7. The method of claims 1, or 2, wherein the liquid, dissolved or suspended active substance is dotted onto a flat pharmaceutical carrier in desired geometrical distributions..]. .[.8. The method of claims 1, or 2, wherein the liquid, dissolved or suspended active substance is dotted onto specific zones of a flat pharmaceutical carrier in doses different from one another..]. .[.9. The method of claims 1, wherein the liquid, dissolved or suspended active substance is mixed with a dyestuff and is dotted onto a pharmaceutical carrier to form a coding or letter characters..].

References Cited (Backward Citations)

US2836291A Cited
US3007848A Cited
US4139589A Cited
US4126503A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1987-12-11 1988-06-11 1988-12-11 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1991-12-11 1992-06-11 1992-12-11 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1995-12-11 1996-06-11 1996-12-11 $7700.00 Window Closed / Lapsed

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