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US8148431B2 Expired / Lapsed US ⏱️ 0.0 years remaining

Osteogenesis promoter containing β-cryptoxanthin as the active ingredient

Assignee: Kemin Foods LC
•
Filing: 2003-10-03
•
Granted: 2012-04-03
•
Expires: 2023-10-03
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Abstract

Abstract It is intended to provide an osteogenesis promoter having a remarkable effect of positively promoting osteogenesis and thus preventing/treating bone diseases; a preventive/a remedy for bone diseases such as osteoporosis having both of an osteogenesis-promoting effect and a bone resorption-inhibiting effect; and a method of screening an active ingredient for preventing/treating bone diseases by using a compound having both of an osteogenesis-promoting effect and a bone resorption-inhibiting effect as a lead compound. It is confirmed that beta-cryptoxanthin, which occurs in a large amount in peel and sarcocarp of satsuma orange, has an osteogenesis-promoting effect and a therapeutic effect on bone disease. Thus, beta-cryptoxanthin or its composition is used as an osteogenesis promoter, a preventive/a remedy for bone diseases, a functional food or a food material for preventing/treating bone diseases and a feed composition.

Inventors

  • 👤 Masayoshi Yamaguchi

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 23:30
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/045; A61K31/07; A23; A23K; A23K20/00; A23K20/10; A23K20/174; A23K20/179; A23L; A23L33/00; A23L33/10; A23L33/105; A61P; A61P19/00; A61P19/08; A61P19/10

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 39 words
A method of ameliorating bone loss problems associated with aging in a person in need thereof, comprising administering to the person in need thereof an amount of purified β-cryptoxanthin effective to ameliorate the bone loss problems associated with aging.
Claim 2
Independent Claim 39 words
A method of ameliorating bone loss problems associated with aging in a person in need thereof, comprising administering to the person in need thereof an amount of purified β-cryptoxanthin effective to ameliorate the bone loss problems associated with aging.
Claim 3
Dependent Claim 24 words
A method as defined in claim 1 , wherein the amount is between about 100 and about 1000 μg per kilogram of body weight.
Claim 4
Dependent Claim 20 words
A method as defined in claim 1 , wherein the amount is between about 0.5 mg and about 10 mg.
Claim 5
Independent Claim 29 words
A method of ameliorating osteoporosis in a person in need thereof, comprising administering to the person in need thereof an amount of purified β-cryptoxanthin effective to ameliorate the osteoporosis.
Claim 6
Independent Claim 29 words
A method of ameliorating osteoporosis in a person in need thereof, comprising administering to the person in need thereof an amount of purified β-cryptoxanthin effective to ameliorate the osteoporosis.
Claim 7
Dependent Claim 24 words
A method as defined in claim 4 , wherein the amount is between about 100 and about 1000 μg per kilogram of body weight.
Claim 8
Dependent Claim 20 words
A method as defined in claim 4 , wherein the amount is between about 0.5 mg and about 10 mg.
Claim 9
Independent Claim 28 words
A method of promoting osteogenesis in a person in need thereof, comprising administering to the person in need thereof an amount of purified β-cryptoxanthin effective to promote osteogenesis.
Claim 10
Independent Claim 28 words
A method of promoting osteogenesis in a person in need thereof, comprising administering to the person in need thereof an amount of purified β-cryptoxanthin effective to promote osteogenesis.
Claim 11
Dependent Claim 24 words
A method as defined in claim 7 , wherein the amount is between about 100 and about 1000 μg per kilogram of body weight.
Claim 12
Dependent Claim 20 words
A method as defined in claim 7 , wherein the amount is between about 0.5 mg and about 10 mg.

References Cited (Backward Citations)

JPH07215849A Cited
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JPH1036256A Cited
JPH10114653A Cited
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JPH10218767A Cited
JPH10279492A Cited
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JP2001521943A Cited
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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2015-04-03 2015-10-03 2016-04-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2019-04-03 2019-10-03 2020-04-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2023-04-03 2023-10-03 2024-04-03 $7700.00 Window Closed / Lapsed

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