US7803185B2 — Method of implantation of a heart valve prosthesi…

Claim 1

Independent Claim 217 words

A method for implanting a heart valve prosthesis into a patient's heart, the method comprising: inserting the heart valve prosthesis into a barrel of an implanter, such that the prosthesis has a reduced cross-sectional dimension relative to a fully expanded cross-sectional dimension of the prosthesis; opening a patient's chest; creating an opening in tissue located within the open patient's chest to provide a substantially direct path that extends from the opening to a desired implantation site in the patient's heart, the opening in the tissue being created in the patient's pulmonary artery, the patient's aorta or heart muscle of the patient so that the opening opposes the desired implantation site; passing a length of the barrel through the opening in the tissue to position an end of the barrel of the implanter adjacent the desired implantation site in the patient's heart such that the end of the barrel and the opening are along the direct path; discharging the heart valve prosthesis from the barrel of the implanter adjacent the desired implantation site; and expanding the heart valve prosthesis at the desired implantation site from the reduced cross-sectional dimension toward the expanded cross-sectional dimension, such that an exterior portion of the heart valve prosthesis engages adjacent tissue to mitigate movement of the prosthesis relative to the adjacent tissue.

Claim 2

Independent Claim 217 words

A method for implanting a heart valve prosthesis into a patient's heart, the method comprising: inserting the heart valve prosthesis into a barrel of an implanter, such that the prosthesis has a reduced cross-sectional dimension relative to a fully expanded cross-sectional dimension of the prosthesis; opening a patient's chest; creating an opening in tissue located within the open patient's chest to provide a substantially direct path that extends from the opening to a desired implantation site in the patient's heart, the opening in the tissue being created in the patient's pulmonary artery, the patient's aorta or heart muscle of the patient so that the opening opposes the desired implantation site; passing a length of the barrel through the opening in the tissue to position an end of the barrel of the implanter adjacent the desired implantation site in the patient's heart such that the end of the barrel and the opening are along the direct path; discharging the heart valve prosthesis from the barrel of the implanter adjacent the desired implantation site; and expanding the heart valve prosthesis at the desired implantation site from the reduced cross-sectional dimension toward the expanded cross-sectional dimension, such that an exterior portion of the heart valve prosthesis engages adjacent tissue to mitigate movement of the prosthesis relative to the adjacent tissue.

Claim 3

Dependent Claim 22 words

The method of claim 1 , the expanding occurring automatically in response to removal of the heart valve prosthesis from the barrel.

Claim 4

Dependent Claim 12 words

The method of claim 1 occurring in the absence of caridiopulmonary bypass.

Claim 5

Dependent Claim 35 words

The method of claim 1 , further comprising urging a portion of the tissue that surrounds the opening in the tissue into engagement with part of the implanter to mitigate blood loss through the opening.

Claim 6

Dependent Claim 40 words

The method of claim 4 , the urging further comprising applying a purse string around the opening and tightening the purse string around an adjacent part of the implanter at the opening to mitigate the blood loss through the opening.

Claim 7

Dependent Claim 64 words

The method of claim 1 , the heart valve prosthesis further comprising a generally cylindrical support extending between opposed ends thereof, a plurality of elongated support features extending generally axially between the opposed ends of the support, the support features being interconnected at ends of the support, and a tissue valve mounted within the support so as to radially expand commensurately with the support.

Claim 8

Dependent Claim 39 words

The method of claim 6 , the support further comprising a generally circular array of biasing elements at each end of the support that interconnect adjacent support features and urge the interconnected adjacent support features apart from each other.

Claim 9

Dependent Claim 60 words

The method of claim 6 , the support further comprising a set of projections at each of the opposed ends of the support and biased to extend axially and radially outwardly from the support, the projections engaging adjacent tissue after the heart valve prosthesis expands to the expanded cross-sectional dimension to help anchor the prosthesis relative to the patient's heart.

Claim 10

Dependent Claim 38 words

The method of claim 1 , further comprising attaching a length of at least one suture to the prosthesis and, after discharging the prosthesis, using the at least one suture to adjust the relative position of the prosthesis.

Claim 11

Independent Claim 196 words

A method for implanting a heart valve prosthesis into a patient's heart, the method comprising: inserting the heart valve prosthesis into a generally cylindrical and elongated enclosure, such that the prosthesis has a reduced cross-sectional dimension corresponding to a dimension of the cylindrical enclosure, the prosthesis being configured to self-expand from the reduced cross-sectional dimension to an expanded cross-sectional dimension, which is greater than the reduced cross-sectional dimension; creating an opening in tissue to provide a substantially linear path extending along a line of sight from the opening to a desired implantation position for replacing a heart valve in the patient's heart; passing an open end of the cylindrical enclosure through the opening; positioning the open end of the cylindrical enclosure adjacent the desired implantation position in the patient's heart such that the open end of the cylindrical enclosure and the opening; discharging the heart valve prosthesis from the cylindrical enclosure at the desired implantation position, whereupon the heart valve prosthesis expands from the reduced cross-sectional dimension to an expanded cross-sectional dimension, such that an exterior portion of the heart valve prosthesis engages adjacent tissue to mitigate movement of the prosthesis relative to the adjacent tissue.

Claim 12

Independent Claim 196 words

A method for implanting a heart valve prosthesis into a patient's heart, the method comprising: inserting the heart valve prosthesis into a generally cylindrical and elongated enclosure, such that the prosthesis has a reduced cross-sectional dimension corresponding to a dimension of the cylindrical enclosure, the prosthesis being configured to self-expand from the reduced cross-sectional dimension to an expanded cross-sectional dimension, which is greater than the reduced cross-sectional dimension; creating an opening in tissue to provide a substantially linear path extending along a line of sight from the opening to a desired implantation position for replacing a heart valve in the patient's heart; passing an open end of the cylindrical enclosure through the opening; positioning the open end of the cylindrical enclosure adjacent the desired implantation position in the patient's heart such that the open end of the cylindrical enclosure and the opening; discharging the heart valve prosthesis from the cylindrical enclosure at the desired implantation position, whereupon the heart valve prosthesis expands from the reduced cross-sectional dimension to an expanded cross-sectional dimension, such that an exterior portion of the heart valve prosthesis engages adjacent tissue to mitigate movement of the prosthesis relative to the adjacent tissue.

Claim 13

Dependent Claim 47 words

The method of claim 10 , the cylindrical enclosure being substantially rigid and substantially linear, such that when the open end of the cylindrical enclosure is positioned adjacent the desired implantation position, the open end of the cylindrical enclosure and the opening are along the linear path.

Claim 14

Dependent Claim 34 words

The method of claim 11 , further comprising urging an adjacent part of the tissue that surrounds the opening into engagement with part of the cylindrical enclosure to mitigate blood loss through the opening.

Claim 15

Dependent Claim 45 words

The method of claim 12 , the urging further comprising applying a purse string around the adjacent part of the blood vessel that surrounds the opening and tightening the purse string around part of the cylindrical enclosure to mitigate the blood loss through the opening.

Claim 16

Dependent Claim 14 words

The method of claim 10 , the tissue comprising heart muscle of the patient.

Claim 17

Dependent Claim 50 words

The method of claim 10 , further comprising attaching a length of at least one suture to the prosthesis and, after discharging the prosthesis, using the at least one suture, part of which extends from the heart valve prosthesis through the opening, to adjust the relative position of the prosthesis.

Claim 18

Dependent Claim 80 words

The method of claim 10 , wherein the heart valve prosthesis further comprises: a generally cylindrical support extending between opposed ends thereof, a plurality of support features extend generally axially between the opposed ends of the support and are interconnected so as to bias the support radially outwardly; and a natural tissue heart valve mounted within the support to define a supported valve, the supported valve being deformable between a reduced cross sectional dimension and the expanded cross sectional dimension.

Claim 19

Dependent Claim 22 words

The method of claim 10 , wherein the opening is created in one of the patient's pulmonary artery or the patient's aorta.

Claim 20

Independent Claim 151 words

A method for implanting a heart valve prosthesis, comprising: creating an opening in a tissue that provides a linear path extending from the opening to a desired implantation position in the patient's heart, the opening being created in one of the patient's pulmonary artery, the patient's aorta or heart muscle of the patient to provide the linear path; passing a length of a cylindrical barrel through the opening to position an end of the barrel at the desired position in the patient's heart, an expandable heart valve prosthesis being located within the barrel; and discharging the heart valve prosthesis from the barrel to the desired implantation position for replacing a heart valve in the patient's heart so that the discharged heart valve prosthesis expands to an expanded cross sectional dimension that contacts adjacent tissue in the patient's heart to mitigate movement of the heart valve prosthesis relative to the patient's heart.

Claim 21

Independent Claim 151 words

A method for implanting a heart valve prosthesis, comprising: creating an opening in a tissue that provides a linear path extending from the opening to a desired implantation position in the patient's heart, the opening being created in one of the patient's pulmonary artery, the patient's aorta or heart muscle of the patient to provide the linear path; passing a length of a cylindrical barrel through the opening to position an end of the barrel at the desired position in the patient's heart, an expandable heart valve prosthesis being located within the barrel; and discharging the heart valve prosthesis from the barrel to the desired implantation position for replacing a heart valve in the patient's heart so that the discharged heart valve prosthesis expands to an expanded cross sectional dimension that contacts adjacent tissue in the patient's heart to mitigate movement of the heart valve prosthesis relative to the patient's heart.

Claim 22

Dependent Claim 35 words

The method of claim 18 , further comprising, after discharging the heart valve prosthesis, using at least one suture, which extends from the prosthesis through the opening, to adjust the relative position of the prosthesis.

Claim 23

Dependent Claim 78 words

The method of claim 18 , wherein the heart valve prosthesis: a generally cylindrical support extending between opposed ends thereof, a plurality of support features extend generally axially between the opposed ends of the support and are interconnected so as to bias the support radially outwardly; and a natural tissue heart valve mounted within the support to define a supported valve, the supported valve being deformable between the reduced cross sectional dimension and the expanded cross sectional dimension.

Claim 24

Independent Claim 186 words

A method for implanting a heart valve prosthesis into a patient's heart, the method comprising: placing the heart valve prosthesis into an elongated barrel of an implanter, such that the prosthesis has a reduced cross-sectional dimension relative to an expanded cross-sectional dimension of the prosthesis; creating an opening through the patient's heart muscle such that a desired implantation site in the patient's heart is in a line of sight with the opening; inserting a length of the barrel through the opening in the heart muscle to position an end of the barrel to a location that is adjacent the desired implantation site in the patient's heart, such that the end of the barrel is in a line of sight with the opening; discharging the heart valve prosthesis from the barrel of the implanter at the location adjacent the desired implantation site; and expanding the heart valve prosthesis at the desired implantation site from the reduced cross-sectional dimension toward the expanded cross-sectional dimension, such that an exterior portion of the heart valve prosthesis engages adjacent tissue to mitigate movement of the prosthesis relative to the adjacent tissue.

Claim 25

Independent Claim 186 words

A method for implanting a heart valve prosthesis into a patient's heart, the method comprising: placing the heart valve prosthesis into an elongated barrel of an implanter, such that the prosthesis has a reduced cross-sectional dimension relative to an expanded cross-sectional dimension of the prosthesis; creating an opening through the patient's heart muscle such that a desired implantation site in the patient's heart is in a line of sight with the opening; inserting a length of the barrel through the opening in the heart muscle to position an end of the barrel to a location that is adjacent the desired implantation site in the patient's heart, such that the end of the barrel is in a line of sight with the opening; discharging the heart valve prosthesis from the barrel of the implanter at the location adjacent the desired implantation site; and expanding the heart valve prosthesis at the desired implantation site from the reduced cross-sectional dimension toward the expanded cross-sectional dimension, such that an exterior portion of the heart valve prosthesis engages adjacent tissue to mitigate movement of the prosthesis relative to the adjacent tissue.

Claim 26

Dependent Claim 15 words

The method of claim 21 , wherein the desired implantation site is the pulmonic position.

Claim 27

Dependent Claim 15 words

The method of claim 21 , wherein the desired implantation site is the aortic position.

Claim 28

Dependent Claim 29 words

The method of claim 21 , wherein the expansion of the heart valve prosthesis at the desired implantation site occurs automatically in response to be discharged from the barrel.

Claim 29

Dependent Claim 51 words

The method of claim 21 , wherein the barrel further comprises a substantially rigid elongated cylinder that extends axially from a first end and terminates in the end of the barrel, the substantially rigid elongated cylinder having an inner diameter in a range from about 5 mm to about 15 mm.

Annuity Stage	Window Opens	Payment Deadline	Surcharge Period Until	Estimated Fee	Status
3.5 Years (Year 4)	2013-09-27	2014-03-29	2014-09-28	$2000.00	Window Closed / Lapsed
7.5 Years (Year 8)	2017-09-27	2018-03-29	2018-09-28	$3760.00	Window Closed / Lapsed
11.5 Years (Year 12)	2021-09-27	2022-03-29	2022-09-28	$7700.00	Window Closed / Lapsed

Method of implantation of a heart valve prosthesis through a tubular catheter

Abstract

Inventors

Bibliographic Details

Claims Analysis

References Cited (Backward Citations)

USPTO Annuity & Maintenance Windows

Assigned Categories & Tags

Assign Category Tag