US7252682B2
Expired / Lapsed
US
⏱️ 0.0 years remaining
Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body
Assignee: CoreValve SA
•
Filing: 2002-07-04
•
Granted: 2007-08-07
•
Expires: 2022-07-04
Abstract
Abstract The present invention is an assembly comprising a prosthetic valve to be implanted; a radially expandable stent comprising at least one zone intended to be expanded to allow the stent, in the expanded state, to bear against the wall of the body duct to be fitted with the valve, this bearing making it possible to immobilize this stent with respect to this wall; and means for mounting the valve with respect to the stent, making it possible to connect the valve to the stent in such a way that the placement of the stent allows the valve to be mounted in the body duct, and expansion means such as a balloon catheter being provided to trigger expansion of the stent at the implantation site. According to the invention, the valve and the stent are designed in such a way that, at the moment when the stent is expanded, the valve is situated outside the zone or zones of the stent that are subjected to said expansion means. The invention thus consists in separating the valve and said zone or zones to be expanded, so that the expansion of the stent can be effected with an expansion force suitable for perfect anchoring of this stent in the wall of the body duct to be fitted with the valve, and without any risk of destruction or damage of the valve.
Inventors
- 👤 Jacques Seguin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:47
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/24; A61F2/2403; A61F2/2412; A61F2/2418; A61F2220/00; A61F2220/0008; A61F2220/0016; A61F2220/0025; A61F2220/005; A61F2230/00; A61F2230/0063; A61F2230/0067; A61F2250/00; A61F2250/0058; A61F2250/006
Claims Analysis
Total Claims: 104
Claim 1
Independent Claim
161 words
A prosthetic valve assembly comprising: an implantable prosthetic valve; a radially expandable stent comprising at least one expandable zone that is configured, in an expanded state, to bear against a wall of the native body lumen in a manner so as to resist migration; and means for mounting the valve on the stent such that, when expanded, the valve is positioned outside of the zone; wherein the mounting means is configured such that the valve is axially movable with respect to the stent between a position of non-implantation outside the first zone to be expanded, and a position of implantation, which it can reach after expansion of the stent, in which it is immobilized axially with respect to the stent; and wherein the mounting means comprises at least one band integrated in the peripheral wall of the valve and having a shape memory, so that it keeps the valve pressed against the stent in the position of implantation of this valve.
Claim 2
Dependent Claim
161 words
A prosthetic valve assembly comprising: an implantable prosthetic valve; a radially expandable stent comprising at least one expandable zone that is configured, in an expanded state, to bear against a wall of the native body lumen in a manner so as to resist migration; and means for mounting the valve on the stent such that, when expanded, the valve is positioned outside of the zone; wherein the mounting means is configured such that the valve is axially movable with respect to the stent between a position of non-implantation outside the first zone to be expanded, and a position of implantation, which it can reach after expansion of the stent, in which it is immobilized axially with respect to the stent; and wherein the mounting means comprises at least one band integrated in the peripheral wall of the valve and having a shape memory, so that it keeps the valve pressed against the stent in the position of implantation of this valve.
Claim 3
Dependent Claim
24 words
The assembly of claim 1 , further comprising expansion means to expand at least the zone of the stent at the desired implantation site.
Claim 4
Dependent Claim
12 words
The assembly of claim 1 , wherein the band comprises a wire.
Claim 5
Dependent Claim
13 words
The assembly of claim 1 , wherein the band is circular in shape.
Claim 6
Dependent Claim
13 words
The assembly of claim 1 , wherein the band is helical in shape.
Claim 7
Dependent Claim
58 words
The assembly of claim 1 , wherein the mounting means is configured such that, beyond a threshold of expansion of the stent, said means permits a different amount of expansion of the valve and the stent, whereby the variation in the degree of expansion of the stent does not substantially impact the degree of expansion of the valve.
Claim 8
Dependent Claim
16 words
The assembly of claim 1 , further comprising means for limiting the expansion of the valve.
Claim 9
Dependent Claim
34 words
The assembly of claim 1 , wherein the valve comprises a peripheral wall with a tapered diameter in the axial direction and the zone of the stent supporting the valve has a corresponding shape.
Claim 10
Dependent Claim
43 words
The assembly of claim 1 , wherein the stent comprises a middle portion having a smaller diameter than at end portions thereof, the valve having a shape corresponding to that zone of the stent in whose area it is intended to be mounted.
Claim 11
Dependent Claim
23 words
The assembly of claim 1 , further comprising a sheath that comprises an impermeable biocompatible material and at least partially covers the stent.
Claim 12
Dependent Claim
24 words
The assembly of claim 10 , wherein the sheath has lateral openings that are configured to be positioned opposite the coronary ostia when implanted.
Claim 13
Dependent Claim
33 words
The assembly of claim 1 , wherein the stent comprises a cylindrical portion that is configured to bear against the native cardiac valvular ring and a distal portion connected to the cylindrical portion.
Claim 14
Dependent Claim
41 words
The assembly of claim 1 , wherein the stent comprises a tapered proximal portion whose diameter decreases in the distal direction and is configured to, upon implantation, to bear against the wall of the ventricle or corresponding auricle of the heart.
Claim 15
Dependent Claim
47 words
The assembly of claim 13 , further comprising a supplementary bearing portion on the stent connected by rods to the distal portion or to the cylindrical portion, the rods configured of sufficient length so that, when implanted, the supplementary bearing portion is positioned beyond the coronary ostia.
Claim 16
Dependent Claim
16 words
The assembly of claim 1 , further comprising retractable hooks on the stent to minimize migration.
Claim 17
Dependent Claim
16 words
The assembly of claim 1 , wherein the stent comprises a portion of high radial force.
Claim 18
Dependent Claim
112 words
A prosthetic valve assembly comprising: an implantable prosthetic valve; a radially expandable stent comprising at least one expandable zone that is configured, in an expanded state, to bear against a wall of the native body lumen in a manner so as to resist migration; and means for mounting the valve on the stent such that, when expanded, the valve is positioned outside of the zone; wherein the stent comprises a middle portion having a smaller diameter than at end portions thereof, the valve having a shape corresponding to that zone of the stent in whose area it is intended to be mounted; and wherein the middle portion forms two inverted truncated cones.
Claim 19
Dependent Claim
112 words
A prosthetic valve assembly comprising: an implantable prosthetic valve; a radially expandable stent comprising at least one expandable zone that is configured, in an expanded state, to bear against a wall of the native body lumen in a manner so as to resist migration; and means for mounting the valve on the stent such that, when expanded, the valve is positioned outside of the zone; wherein the stent comprises a middle portion having a smaller diameter than at end portions thereof, the valve having a shape corresponding to that zone of the stent in whose area it is intended to be mounted; and wherein the middle portion forms two inverted truncated cones.
Claim 20
Dependent Claim
24 words
The assembly of claim 17 , further comprising expansion means to expand at least the zone of the stent at the desired implantation site.
Claim 21
Dependent Claim
61 words
The assembly of claim 17 , wherein the mounting means is configured such that the valve is axially movable with respect to the stent between a position of non-implantation outside the first zone to be expanded, and a position of implantation, which it can reach after expansion of the stent, in which it is immobilized axially with respect to the stent.
Claim 22
Dependent Claim
27 words
The assembly of claim 19 , wherein the mounting means comprises radially positioned fastening members mounted on the valve configured to be inserted into the body wall.
Claim 23
Dependent Claim
26 words
The assembly of claim 20 , wherein the fastening member are configured to insert into the body upon a pivoting of the valve about its axis.
Claim 24
Dependent Claim
29 words
The assembly of claim 20 , wherein the fastening member are configured to insert into the body upon a longitudinal movement of the valve with respect to the stent.
Claim 25
Dependent Claim
15 words
The assembly of claim 20 , wherein the fastening members comprise spikes, hooks or claws.
Claim 26
Dependent Claim
46 words
The assembly of claim 19 , wherein the mounting means comprises at least one band integrated in the peripheral wall of the valve and having a shape memory, so that it keeps the valve pressed against the stent in the position of implantation of this valve.
Claim 27
Dependent Claim
12 words
The assembly of claim 24 , wherein the band comprises a wire.
Claim 28
Dependent Claim
13 words
The assembly of claim 24 , wherein the band is circular in shape.
Claim 29
Dependent Claim
13 words
The assembly of claim 24 , wherein the band is helical in shape.
Claim 30
Dependent Claim
12 words
The assembly of claim 19 , wherein the mounting means comprises conduits.
Claim 31
Dependent Claim
31 words
The assembly of claim 28 , further comprising rods configured to engage and slide through the conduits as the valve moves from its position of non-implantation to its position of implantation.
Claim 32
Dependent Claim
23 words
The assembly of claim 29 , further comprising means to immobilize the conduits with respect to the rods in the position of implantation.
Claim 33
Dependent Claim
27 words
The assembly of claim 30 , further comprising wires connected to the rods and configured to pass through said conduits to guide said rods in the conduits.
Claim 34
Dependent Claim
58 words
The assembly of claim 17 , wherein the mounting means is configured such that, beyond a threshold of expansion of the stent, said means permits a different amount of expansion of the valve and the stent, whereby the variation in the degree of expansion of the stent does not substantially impact the degree of expansion of the valve.
Claim 35
Dependent Claim
16 words
The assembly of claim 17 , further comprising means for limiting the expansion of the valve.
Claim 36
Dependent Claim
34 words
The assembly of claim 17 , wherein the valve comprises a peripheral wall with a tapered diameter in the axial direction and the zone of the stent supporting the valve has a corresponding shape.
Claim 37
Dependent Claim
85 words
The assembly of claim 17 , wherein the valve has a peripheral wall and the stent has, in the distal continuation of that zone of the stent intended to receive the valve, a foldable portion movable between an extended position, in which it is situated in the distal continuation of said zone, and a folded position, in which it is placed against the inner face of the peripheral wall of the valve, and traps this peripheral wall between it and said zone of the stent.
Claim 38
Dependent Claim
19 words
The assembly of claim 35 , further comprising retaining means for keeping this foldable portion in a folded position.
Claim 39
Dependent Claim
23 words
The assembly of claim 17 , further comprising a sheath that comprises an impermeable biocompatible material and at least partially covers the stent.
Claim 40
Dependent Claim
24 words
The assembly of claim 37 , wherein the sheath has lateral openings that are configured to be positioned opposite the coronary ostia when implanted.
Claim 41
Dependent Claim
33 words
The assembly of claim 17 , wherein the stent comprises a cylindrical portion that is configured to bear against the native cardiac valvular ring and a distal portion connected to the cylindrical portion.
Claim 42
Dependent Claim
41 words
The assembly of claim 17 , wherein the stent comprises a tapered proximal portion whose diameter decreases in the distal direction and is configured to, upon implantation, to bear against the wall of the ventricle or corresponding auricle of the heart.
Claim 43
Dependent Claim
47 words
The assembly of claim 40 , further comprising a supplementary bearing portion on the stent connected by rods to the distal portion or to the cylindrical portion, the rods configured of sufficient length so that, when implanted, the supplementary bearing portion is positioned beyond the coronary ostia.
Claim 44
Dependent Claim
16 words
The assembly of claim 17 , further comprising retractable hooks on the stent to minimize migration.
Claim 45
Dependent Claim
16 words
The assembly of claim 17 , wherein the stent comprises a portion of high radial force.
Claim 46
Dependent Claim
111 words
A prosthetic valve assembly comprising: an implantable prosthetic valve; a radially expandable stent comprising at least one expandable zone that is configured, in an expanded state, to bear against a wall of the native body lumen in a manner so as to resist migration; and means for mounting the valve on the stent such that, when expanded, the valve is positioned outside of the zone; wherein the stent comprises a middle portion having a smaller diameter than at end portions thereof, the valve having a shape corresponding to that zone of the stent in whose area it is intended to be mounted; and wherein the middle portion forms an hourglass shape.
Claim 47
Dependent Claim
111 words
A prosthetic valve assembly comprising: an implantable prosthetic valve; a radially expandable stent comprising at least one expandable zone that is configured, in an expanded state, to bear against a wall of the native body lumen in a manner so as to resist migration; and means for mounting the valve on the stent such that, when expanded, the valve is positioned outside of the zone; wherein the stent comprises a middle portion having a smaller diameter than at end portions thereof, the valve having a shape corresponding to that zone of the stent in whose area it is intended to be mounted; and wherein the middle portion forms an hourglass shape.
Claim 48
Dependent Claim
24 words
The assembly of claim 44 , further comprising expansion means to expand at least the zone of the stent at the desired implantation site.
Claim 49
Dependent Claim
61 words
The assembly of claim 44 , wherein the mounting means is configured such that the valve is axially movable with respect to the stent between a position of non-implantation outside the first zone to be expanded, and a position of implantation, which it can reach after expansion of the stent, in which it is immobilized axially with respect to the stent.
Claim 50
Dependent Claim
27 words
The assembly of claim 46 , wherein the mounting means comprises radially positioned fastening members mounted on the valve configured to be inserted into the body wall.
Claim 51
Dependent Claim
26 words
The assembly of claim 47 , wherein the fastening member are configured to insert into the body upon a pivoting of the valve about its axis.
Claim 52
Dependent Claim
29 words
The assembly of claim 47 , wherein the fastening member are configured to insert into the body upon a longitudinal movement of the valve with respect to the stent.
Claim 53
Dependent Claim
15 words
The assembly of claim 47 , wherein the fastening members comprise spikes, hooks or claws.
Claim 54
Dependent Claim
46 words
The assembly of claim 46 , wherein the mounting means comprises at least one band integrated in the peripheral wall of the valve and having a shape memory, so that it keeps the valve pressed against the stent in the position of implantation of this valve.
Claim 55
Dependent Claim
12 words
The assembly of claim 51 , wherein the band comprises a wire.
Claim 56
Dependent Claim
13 words
The assembly of claim 51 , wherein the band is circular in shape.
Claim 57
Dependent Claim
13 words
The assembly of claim 51 , wherein the band is helical in shape.
Claim 58
Dependent Claim
12 words
The assembly of claim 46 , wherein the mounting means comprises conduits.
Claim 59
Dependent Claim
31 words
The assembly of claim 55 , further comprising rods configured to engage and slide through the conduits as the valve moves from its position of non-implantation to its position of implantation.
Claim 60
Dependent Claim
23 words
The assembly of claim 56 , further comprising means to immobilize the conduits with respect to the rods in the position of implantation.
Claim 61
Dependent Claim
27 words
The assembly of claim 57 , further comprising wires connected to the rods and configured to pass through said conduits to guide said rods in the conduits.
Claim 62
Dependent Claim
58 words
The assembly of claim 44 , wherein the mounting means is configured such that, beyond a threshold of expansion of the stent, said means permits a different amount of expansion of the valve and the stent, whereby the variation in the degree of expansion of the stent does not substantially impact the degree of expansion of the valve.
Claim 63
Dependent Claim
16 words
The assembly of claim 44 , further comprising means for limiting the expansion of the valve.
Claim 64
Dependent Claim
34 words
The assembly of claim 44 , wherein the valve comprises a peripheral wall with a tapered diameter in the axial direction and the zone of the stent supporting the valve has a corresponding shape.
Claim 65
Dependent Claim
85 words
The assembly of claim 44 , wherein the valve has a peripheral wall and the stent has, in the distal continuation of that zone of the stent intended to receive the valve, a foldable portion movable between an extended position, in which it is situated in the distal continuation of said zone, and a folded position, in which it is placed against the inner face of the peripheral wall of the valve, and traps this peripheral wall between it and said zone of the stent.
Claim 66
Dependent Claim
19 words
The assembly of claim 62 , further comprising retaining means for keeping this foldable portion in a folded position.
Claim 67
Dependent Claim
23 words
The assembly of claim 44 , further comprising a sheath that comprises an impermeable biocompatible material and at least partially covers the stent.
Claim 68
Dependent Claim
24 words
The assembly of claim 64 , wherein the sheath has lateral openings that are configured to be positioned opposite the coronary ostia when implanted.
Claim 69
Dependent Claim
33 words
The assembly of claim 44 , wherein the stent comprises a cylindrical portion that is configured to bear against the native cardiac valvular ring and a distal portion connected to the cylindrical portion.
Claim 70
Dependent Claim
41 words
The assembly of claim 44 , wherein the stent comprises a tapered proximal portion whose diameter decreases in the distal direction and is configured to, upon implantation, to bear against the wall of the ventricle or corresponding auricle of the heart.
Claim 71
Dependent Claim
47 words
The assembly of claim 67 , further comprising a supplementary bearing portion on the stent connected by rods to the distal portion or to the cylindrical portion, the rods configured of sufficient length so that, when implanted, the supplementary bearing portion is positioned beyond the coronary ostia.
Claim 72
Dependent Claim
16 words
The assembly of claim 44 , further comprising retractable hooks on the stent to minimize migration.
Claim 73
Dependent Claim
16 words
The assembly of claim 44 , wherein the stent comprises a portion of high radial force.
Claim 74
Dependent Claim
80 words
A prosthetic valve assembly comprising: an implantable prosthetic valve; a radially expandable stent comprising at least one expandable zone that is configured, in an expanded state, to bear against a wall of the native body lumen in a manner so as to resist migration; a sheath that comprises an impermeable biocompatible material and at least partially covers the stent; and means for mounting the valve on the stent such that, when expanded, the valve is positioned outside of the zone.
Claim 75
Dependent Claim
80 words
A prosthetic valve assembly comprising: an implantable prosthetic valve; a radially expandable stent comprising at least one expandable zone that is configured, in an expanded state, to bear against a wall of the native body lumen in a manner so as to resist migration; a sheath that comprises an impermeable biocompatible material and at least partially covers the stent; and means for mounting the valve on the stent such that, when expanded, the valve is positioned outside of the zone.
Claim 76
Dependent Claim
24 words
The assembly of claim 71 , further comprising expansion means to expand at least the zone of the stent at the desired implantation site.
Claim 77
Dependent Claim
61 words
The assembly of claim 71 , wherein the mounting means is configured such that the valve is axially movable with respect to the stent between a position of non-implantation outside the first zone to be expanded, and a position of implantation, which it can reach after expansion of the stent, in which it is immobilized axially with respect to the stent.
Claim 78
Dependent Claim
46 words
The assembly of claim 73 , wherein the mounting means comprises at least one band integrated in the peripheral wall of the valve and having a shape memory, so that it keeps the valve pressed against the stent in the position of implantation of this valve.
Claim 79
Dependent Claim
12 words
The assembly of claim 74 , wherein the band comprises a wire.
Claim 80
Dependent Claim
13 words
The assembly of claim 74 , wherein the band is circular in shape.
Claim 81
Dependent Claim
13 words
The assembly of claim 74 , wherein the band is helical in shape.
Claim 82
Dependent Claim
58 words
The assembly of claim 71 , wherein the mounting means is configured such that, beyond a threshold of expansion of the stent, said means permits a different amount of expansion of the valve and the stent, whereby the variation in the degree of expansion of the stent does not substantially impact the degree of expansion of the valve.
Claim 83
Dependent Claim
16 words
The assembly of claim 71 , further comprising means for limiting the expansion of the valve.
Claim 84
Dependent Claim
43 words
The assembly of claim 71 , wherein the stent comprises a middle portion having a smaller diameter than at end portions thereof, the valve having a shape corresponding to that zone of the stent in whose area it is intended to be mounted.
Claim 85
Dependent Claim
24 words
The assembly of claim 71 , wherein the sheath has lateral openings that are configured to be positioned opposite the coronary ostia when implanted.
Claim 86
Dependent Claim
33 words
The assembly of claim 71 , wherein the stent comprises a cylindrical portion that is configured to bear against the native cardiac valvular ring and a distal portion connected to the cylindrical portion.
Claim 87
Dependent Claim
41 words
The assembly of claim 71 , wherein the stent comprises a tapered proximal portion whose diameter decreases in the distal direction and is configured to, upon implantation, to bear against the wall of the ventricle or corresponding auricle of the heart.
Claim 88
Dependent Claim
16 words
The assembly of claim 71 , further comprising retractable hooks on the stent to minimize migration.
Claim 89
Dependent Claim
16 words
The assembly of claim 71 , wherein the stent comprises a portion of high radial force.
Claim 90
Dependent Claim
73 words
A prosthetic valve assembly comprising: an implantable prosthetic valve; a radially expandable stent comprising at least one expandable zone that is configured, in an expanded state, to bear against a wall of the native body lumen in a manner so as to resist migration; means for mounting the valve on the stent such that, when expanded, the valve is positioned outside of the zone; and retractable hooks on the stent to minimize migration.
Claim 91
Dependent Claim
73 words
A prosthetic valve assembly comprising: an implantable prosthetic valve; a radially expandable stent comprising at least one expandable zone that is configured, in an expanded state, to bear against a wall of the native body lumen in a manner so as to resist migration; means for mounting the valve on the stent such that, when expanded, the valve is positioned outside of the zone; and retractable hooks on the stent to minimize migration.
Claim 92
Dependent Claim
24 words
The assembly of claim 86 , further comprising expansion means to expand at least the zone of the stent at the desired implantation site.
Claim 93
Dependent Claim
21 words
The assembly of claim 86 , where in the stent is mounted within a second zone distinct from the first zone.
Claim 94
Dependent Claim
61 words
The assembly of claim 86 , wherein the mounting means is configured such that the valve is axially movable with respect to the stent between a position of non-implantation outside the first zone to be expanded, and a position of implantation, which it can reach after expansion of the stent, in which it is immobilized axially with respect to the stent.
Claim 95
Dependent Claim
58 words
The assembly of claim 86 , wherein the mounting means is configured such that, beyond a threshold of expansion of the stent, said means permits a different amount of expansion of the valve and the stent, whereby the variation in the degree of expansion of the stent does not substantially impact the degree of expansion of the valve.
Claim 96
Dependent Claim
16 words
The assembly of claim 86 , further comprising means for limiting the expansion of the valve.
Claim 97
Dependent Claim
34 words
The assembly of claim 86 , wherein the valve comprises a peripheral wall with a tapered diameter in the axial direction and the zone of the stent supporting the valve has a corresponding shape.
Claim 98
Dependent Claim
43 words
The assembly of claim 86 , wherein the stent comprises a middle portion having a smaller diameter than at end portions thereof, the valve having a shape corresponding to that zone of the stent in whose area it is intended to be mounted.
Claim 99
Dependent Claim
85 words
The assembly of claim 86 , wherein the valve has a peripheral wall and the stent has, in the distal continuation of that zone of the stent intended to receive the valve, a foldable portion movable between an extended position, in which it is situated in the distal continuation of said zone, and a folded position, in which it is placed against the inner face of the peripheral wall of the valve, and traps this peripheral wall between it and said zone of the stent.
Claim 100
Dependent Claim
19 words
The assembly of claim 94 , further comprising retaining means for keeping this foldable portion in a folded position.
Claim 101
Dependent Claim
23 words
The assembly of claim 86 , further comprising a sheath that comprises an impermeable biocompatible material and at least partially covers the stent.
Claim 102
Dependent Claim
24 words
The assembly of claim 96 , wherein the sheath has lateral openings that are configured to be positioned opposite the coronary ostia when implanted.
Claim 103
Dependent Claim
33 words
The assembly of claim 86 , wherein the stent comprises a cylindrical portion that is configured to bear against the native cardiac valvular ring and a distal portion connected to the cylindrical portion.
Claim 104
Dependent Claim
41 words
The assembly of claim 86 , wherein the stent comprises a tapered proximal portion whose diameter decreases in the distal direction and is configured to, upon implantation, to bear against the wall of the ventricle or corresponding auricle of the heart.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2010-08-06 | 2011-02-05 | 2011-08-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2014-08-06 | 2015-02-05 | 2015-08-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2018-08-06 | 2019-02-05 | 2019-08-07 | $7700.00 | Window Closed / Lapsed |