US7250255B2
Expired / Lapsed
US
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Genes with ES cell-specific expression
Assignee: Sumitomo Pharma Co Ltd
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Filing: 2002-05-31
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Granted: 2007-07-31
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Expires: 2022-05-31
Abstract
Abstract The present invention relates to a probe for selecting ES cells, which characteristically contains one of DNAs having base sequences depicted in SEQ ID Nos; 1, 2, 3, 4, 5, 6, 7 and 8, or DNAs having base sequences depicted in SEQ ID Nos; 9, 11, 13, 15, 17, 19, 21, 23 and 41 and a screening method of ES cell using this probe. Preparation of a probe for selecting ES cells becomes feasible by identifying plural gene with ES cell-specific expressions (ECAT genes) and using the information of the base sequences of these gene groups. Efficient selection of ES cell enables supply of a large amount of ES cell expected to be applicable to regenerative medicine.
Inventors
- 👤 Shinya Yamanaka
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 16:08
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/68; C12Q1/6876; C12Q1/6881; C12N; C12N5/00; C12N5/06; C12N5/0602; C12N5/0603; C12N5/0606; C12Q2600/00; C12Q2600/158
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
12 words
An isolated nucleic acid comprising a DNA comprising SEQ ID NO: 15.
Claim 2
Dependent Claim
12 words
An isolated nucleic acid comprising a DNA comprising SEQ ID NO: 15.
Claim 3
Dependent Claim
10 words
A vector comprising the nucleic acid of claim 1 .
Claim 4
Dependent Claim
10 words
An isolated cell comprising the vector of claim 2 .
Claim 5
Dependent Claim
19 words
An isolated probe for selecting mouse ES cells, wherein the probe comprises the nucleic acid of claim 1 .
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2010-07-30 | 2011-01-29 | 2011-07-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2014-07-30 | 2015-01-29 | 2015-07-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2018-07-30 | 2019-01-29 | 2019-07-31 | $7700.00 | Window Closed / Lapsed |