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US7100616B2 Expired / Lapsed US ⏱️ 0.0 years remaining

Bronchoscopic lung volume reduction method

Assignee: Gyrus ACMI Inc
•
Filing: 2003-04-08
•
Granted: 2006-09-05
•
Expires: 2023-04-08
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Abstract

Abstract A method of minimally invasively reducing a volume of a hyper-inflated target section of diseased lung comprising the steps of introducing a bronchoscope into a patient's airway to a position adjacent the target section and equilibrating air within the target section with atmospheric air to at least partially deflate the target lung section; injecting an inflammation-causing substance into the target section to precipitate adhesion of the walls within the target lung section, preventing substantial re-inflation of the target section by occluding an airway upstream of the target section for a period of time, and removing the airway occlusion after the target section has substantially permanently been reduced in volume. The injected substance can be autologous blood or a constituent thereof.

Inventors

  • 👤 Steven C. Springmeyer

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 02:01
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/12; A61B17/12022; A61M; A61M16/00; A61B17/12099; A61B17/12104; A61B17/12131; A61B17/12181; A61B17/12186; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2002/043

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 140 words
A method of minimally invasively performing lung volume reduction to treat a diseased lung section, the method comprising: deflating one or more cavities of at least a portion of the diseased lung section to bring opposing walls surrounding each of one or more of said cavities substantially closer together to provide a substantially reduced cavity; allowing a substantial portion of the opposing walls of said one or more cavities to adhere; implanting a device within an airway of the lung upstream from said one or more cavities, the device configured to substantially preclude inspiration downstream of said device to prevent substantial re-inflation of said one or more cavities; and causing inflammation of a substantial portion of the opposing walls of said one or more cavities by injecting a substance into said target section; wherein the substance comprises autologous whole blood.
Claim 2
Independent Claim 140 words
A method of minimally invasively performing lung volume reduction to treat a diseased lung section, the method comprising: deflating one or more cavities of at least a portion of the diseased lung section to bring opposing walls surrounding each of one or more of said cavities substantially closer together to provide a substantially reduced cavity; allowing a substantial portion of the opposing walls of said one or more cavities to adhere; implanting a device within an airway of the lung upstream from said one or more cavities, the device configured to substantially preclude inspiration downstream of said device to prevent substantial re-inflation of said one or more cavities; and causing inflammation of a substantial portion of the opposing walls of said one or more cavities by injecting a substance into said target section; wherein the substance comprises autologous whole blood.
Claim 3
Dependent Claim 103 words
A minimally invasive method of reducing a volume of an enlarged target region of a lung comprising: guiding a distal end of an bronchoscope to a position adjacent the target region; placing a catheter lumen in fluid communication with an interior of the target region; equilibrating the target region with atmospheric air by opening the lumen to fluid communication with a volume of air at atmospheric pressure; deploying one or more occlusion devices in one or more airways leading into the target region, thereby substantially isolating the target region from air flow in at least an inspiratory direction; and injecting an inflammation-causing substance.
Claim 4
Dependent Claim 103 words
A minimally invasive method of reducing a volume of an enlarged target region of a lung comprising: guiding a distal end of an bronchoscope to a position adjacent the target region; placing a catheter lumen in fluid communication with an interior of the target region; equilibrating the target region with atmospheric air by opening the lumen to fluid communication with a volume of air at atmospheric pressure; deploying one or more occlusion devices in one or more airways leading into the target region, thereby substantially isolating the target region from air flow in at least an inspiratory direction; and injecting an inflammation-causing substance.
Claim 5
Dependent Claim 98 words
A minimally invasive method of reducing a volume of an enlarged target region of a lung comprising: guiding a distal end of an bronchoscope to a position adjacent the target region; placing a catheter lumen in fluid communication with an interior of the target region; equilibrating the target region with atmospheric air by opening the lumen to fluid communication with a volume of air at atmospheric pressure; deploying one or more occlusion devices in one or more airways leading into the target region, thereby substantially isolating the target region from air flow in at least an inspiratory direction.
Claim 6
Dependent Claim 98 words
A minimally invasive method of reducing a volume of an enlarged target region of a lung comprising: guiding a distal end of an bronchoscope to a position adjacent the target region; placing a catheter lumen in fluid communication with an interior of the target region; equilibrating the target region with atmospheric air by opening the lumen to fluid communication with a volume of air at atmospheric pressure; deploying one or more occlusion devices in one or more airways leading into the target region, thereby substantially isolating the target region from air flow in at least an inspiratory direction.
Claim 7
Dependent Claim 72 words
A minimally invasive method of reducing a volume of an enlarged target region of a lung comprising: guiding a distal end of an bronchoscope to a position adjacent the target region; placing a catheter lumen in fluid communication with an interior of the target region; equilibrating the target region with atmospheric air by opening the lumen to fluid communication with a volume of air at atmospheric pressure; and injecting an inflammation-causing substance.
Claim 8
Dependent Claim 72 words
A minimally invasive method of reducing a volume of an enlarged target region of a lung comprising: guiding a distal end of an bronchoscope to a position adjacent the target region; placing a catheter lumen in fluid communication with an interior of the target region; equilibrating the target region with atmospheric air by opening the lumen to fluid communication with a volume of air at atmospheric pressure; and injecting an inflammation-causing substance.
Claim 9
Independent Claim 185 words
A method of minimally invasively performing lung volume reduction to treat a diseased lung section, the method comprising: deflating one or more cavities of at least a portion of the diseased lung section to bring opposing walls surrounding each of one or more of said cavities substantially closer together to provide a substantially reduced cavity, wherein the deflating of the lung section portion comprises exposing a trans-bronchial lumen to the lung section portion to permit at least some of the air within said lung section portion to escape; allowing a substantial portion of the opposing walls of said one or more cavities to adhere; implanting a device within an airway of the lung upstream from said one or more cavities, the device configured to substantially preclude inspiration downstream of said device to prevent substantial re-inflation of said one or more cavities; and causing inflammation of a substantial portion of the opposing walls of said one or more cavities by injecting autologous whole blood into said target section, wherein said injecting step comprises directing said autologous whole blood through a lumen of the same trans-bronchial device.
Claim 10
Independent Claim 185 words
A method of minimally invasively performing lung volume reduction to treat a diseased lung section, the method comprising: deflating one or more cavities of at least a portion of the diseased lung section to bring opposing walls surrounding each of one or more of said cavities substantially closer together to provide a substantially reduced cavity, wherein the deflating of the lung section portion comprises exposing a trans-bronchial lumen to the lung section portion to permit at least some of the air within said lung section portion to escape; allowing a substantial portion of the opposing walls of said one or more cavities to adhere; implanting a device within an airway of the lung upstream from said one or more cavities, the device configured to substantially preclude inspiration downstream of said device to prevent substantial re-inflation of said one or more cavities; and causing inflammation of a substantial portion of the opposing walls of said one or more cavities by injecting autologous whole blood into said target section, wherein said injecting step comprises directing said autologous whole blood through a lumen of the same trans-bronchial device.

References Cited (Backward Citations)

US2981254A Cited
US3540431A Cited
US3657744A Cited
US3788327A Cited
US3874388A Cited
US4014318A Cited
US4086665A Cited
US4250873A Cited
US4212463A Cited
SU852321A1 Cited
US4850999A Cited
US4808183A Cited
US4302854A Cited
US4819664A Cited
US4732152A Cited
US4759758A Cited
US4710192A Cited
US4832680A Cited
US4795449A Cited
US4852568A Cited
US4934999A Cited
US4830003A Cited
US5413599A Cited
US4846836A Cited
US4877025A Cited
US5116564A Cited
US4968294A Cited
US5800339A Cited
US5352240A Cited
US5500014A Cited
US5562608A Cited
US5061274A Cited
US5840081A Cited
US6168614B1 Cited
US5411552A Cited
US5116360A Cited
US5358518A Cited
US5161524A Cited
US5151105A Cited
US5662713A Cited
US5123919A Cited
US5445626A Cited
US6077291A Cited
US5382261A Cited
US5409019A Cited
US5947997A Cited
US5411507A Cited
US5797960A Cited
US5306234A Cited
WO1994026175A1 Cited
US5486154A Cited
US5366478A Cited
US6045560A Cited
US6135729A Cited
US5549628A Cited
US5392775A Cited
US5499995C1 Cited
US5499995A Cited
WO1995032018A1 Cited
US5683451A Cited
US5417226A Cited
US5549626A Cited
US5755770A Cited
US5693089A Cited
WO1996034582A1 Cited
US6312407B1 Cited
US5645565A Cited
US5702409A Cited
US5697968A Cited
US5660175A Cited
US6068638A Cited
US6327772B1 Cited
US6325778B1 Cited
US6325777B1 Cited
WO1997044085A3 Cited
US6355014B1 Cited
US6027525A Cited
US6428561B1 Cited
US5855587A Cited
US5855601A Cited
WO1998000840A1 Cited
US6123663A Cited
US6302893B1 Cited
US6183520B1 Cited
US5725519A Cited
US5752965A Cited
WO1998019633A1 Cited
US6287334B1 Cited
US6135991A Cited
WO1998039047A1 Cited
US5851232A Cited
US6634363B1 Cited
US6488673B1 Cited
US6200333B1 Cited
US6083255A Cited
EP1157663A1 Cited
GB2324729B Cited
WO1998048706A1 Cited
US5957949A Cited
US6245102B1 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2009-09-04 2010-03-06 2010-09-05 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2013-09-04 2014-03-06 2014-09-05 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2017-09-04 2018-03-06 2018-09-05 $7700.00 Window Closed / Lapsed

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