US5161524A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Dosage inhalator with air flow velocity regulating means
Assignee: GlaxoSmithKline LLC
•
Filing: 1991-08-02
•
Granted: 1992-11-10
•
Expires: 2011-08-02
Abstract
Abstract A breath actuated inhalator having a primary and a secondary air flow conduit wherein regulator means are provided in the secondary air flow conduit to planate maximum air flow velocity through the inhaler. By optimizing air flow and velocity rate, the breath actuated inhalator prevents problems associated with excessive inhalation velocity such as dry powder drug compound impingement upon the outside radius of the throat.
Inventors
- 👤 Rix E. Evans
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:40
CPC Classifications
A; A61; A61M; A61M15/00; A61M15/0091; A61M15/0001; A61M15/0013; A61M15/0016; A61M15/002; A61M15/0065; A61M2202/00; A61M2202/06; A61M2202/064
Claims Analysis
Total Claims: 25
Claim 1
Independent Claim
263 words
A portable dosage inhalator for dispensing to a patient a predetermined amount of a pharmacologically active dry powder compound, comprising: a housing defining an air inlet end, said air exit end comprising a nozzle for insertion into the mouth of a patient; a storage chamber formed within said housing for storing said compound to be dispensed by said inhalator; a primary air conduit within said housing and defining a venturi therein; a secondary air conduit within said housing adjacent said primary air conduit; dose introduction means provided within said housing for transporting a predetermined portion of said compound from said storage chamber to said primary air conduit and releasing said compound therein, said dose introduction means adapted to substantially close said primary air conduit to air flow prior to actuation thereof and to allow for air flow through said primary air conduit subsequent to actuation thereof; and regulator means positioned in said secondary air conduit for controlling air flow velocity therethrough, said regulator means normally closing said secondary air conduit to air flow and adapted to move between a first position wherein said secondary air conduit is substantially closed and a second position wherein said secondary air conduit is substantially open in response to air pressure differentials created in the venturi of said primary air conduit as a patient inhales through the nozzle of said air exit end of said housing; whereby said regulator means acts to provide a substantially constant maximum air flow velocity through said inhalator by regulating the air flow through said secondary air conduit during inhalation by a patient.
Claim 2
Dependent Claim
263 words
A portable dosage inhalator for dispensing to a patient a predetermined amount of a pharmacologically active dry powder compound, comprising: a housing defining an air inlet end, said air exit end comprising a nozzle for insertion into the mouth of a patient; a storage chamber formed within said housing for storing said compound to be dispensed by said inhalator; a primary air conduit within said housing and defining a venturi therein; a secondary air conduit within said housing adjacent said primary air conduit; dose introduction means provided within said housing for transporting a predetermined portion of said compound from said storage chamber to said primary air conduit and releasing said compound therein, said dose introduction means adapted to substantially close said primary air conduit to air flow prior to actuation thereof and to allow for air flow through said primary air conduit subsequent to actuation thereof; and regulator means positioned in said secondary air conduit for controlling air flow velocity therethrough, said regulator means normally closing said secondary air conduit to air flow and adapted to move between a first position wherein said secondary air conduit is substantially closed and a second position wherein said secondary air conduit is substantially open in response to air pressure differentials created in the venturi of said primary air conduit as a patient inhales through the nozzle of said air exit end of said housing; whereby said regulator means acts to provide a substantially constant maximum air flow velocity through said inhalator by regulating the air flow through said secondary air conduit during inhalation by a patient.
Claim 3
Dependent Claim
59 words
A portable dosage inhalator according to claim 1 wherein said dose introduction means comprises a slide element extending across the bottom of said storage chamber and traversing the venturi of said primary air conduit prior to actuation thereof, said slide element defining a compound receiving aperture therethrough in the portion positioned beneath said storage chamber prior to actuation thereof.
Claim 4
Dependent Claim
32 words
A portable dosage inhalator according to claim 2 wherein said slide element comprises spring means for resiliently urging said slide from said storage chamber to said primary air conduit upon actuation thereof.
Claim 5
Dependent Claim
64 words
A portable dosage inhalator according to claim 1 wherein said regulator means comprises a normally open diaphragm positioned in said secondary air conduit and in fluid communication with the venturi of said primary air conduit, said diaphragm being adapted to contract and thereby open said secondary air conduit to air flow in response to low pressure in the venturi of said primary air conduit.
Claim 6
Dependent Claim
43 words
A portable dosage inhalator according to claim 1 including actuation means operatively connecting said regulator means and said dose introduction means for actuating said dose introduction means when said regulator means first moves from said normally closed first position toward said second position.
Claim 7
Dependent Claim
36 words
A portable dosage inhalator according to claim 5 wherein said actuation means comprises a link mounted at one end to said regulator means and the other end thereof adapted to releasably engage said dose introduction means.
Claim 8
Dependent Claim
19 words
A portable dosage inhalator according to claim 1 wherein said housing includes a desiccant in said air inlet end.
Claim 9
Dependent Claim
29 words
A portable dosage inhalator according to claim 1 including a non-return valve mounted between said primary air conduit and the nozzle of said inhalator to prevent reverse air flow.
Claim 10
Dependent Claim
295 words
A portable dosage inhalator for dispensing to a patient a predetermined amount of a pharmacologically active dry powder compound, comprising: a housing defining an air inlet end and an air exit end, said air exit end comprising a nozzle for insertion into the mouth of a patient; a storage chamber formed within said housing for storing said compound to be dispensed by said inhalator; air conduit within said housing and defining a venturi therein; a secondary air conduit within said housing adjacent said primary air conduit; dose introduction for transporting a predetermined portion of said compound from said storage chamber to said primary air conduit and releasing said compound therein, said dose introduction means adapted to substantially close said primary air conduit to air flow prior to actuation thereof and to allow for air flow through said primary air conduit subsequent to actuation thereof; regulator means positioned in said secondary air conduit for controlling air flow velocity therethrough, said regulator means normally closing said secondary air conduit to air flow and adapted to move between a first position wherein said secondary air conduit is substantially closed and a second position wherein said secondary air conduit is substantially open in response to air pressure differentials created in the venturi of said primary air conduit as a patient inhales through the nozzle of said air exit end of said housing; and actuation means operatively connecting said regulator means and said dose introduction means for actuating said dose introduction means when said regulator means first moves from said normally closed first position toward said second position; whereby said regulator means acts to provide a substantially constant maximum air flow velocity through said inhalator by regulating the air flow through said secondary air conduit during inhalation by a patient.
Claim 11
Dependent Claim
295 words
A portable dosage inhalator for dispensing to a patient a predetermined amount of a pharmacologically active dry powder compound, comprising: a housing defining an air inlet end and an air exit end, said air exit end comprising a nozzle for insertion into the mouth of a patient; a storage chamber formed within said housing for storing said compound to be dispensed by said inhalator; air conduit within said housing and defining a venturi therein; a secondary air conduit within said housing adjacent said primary air conduit; dose introduction for transporting a predetermined portion of said compound from said storage chamber to said primary air conduit and releasing said compound therein, said dose introduction means adapted to substantially close said primary air conduit to air flow prior to actuation thereof and to allow for air flow through said primary air conduit subsequent to actuation thereof; regulator means positioned in said secondary air conduit for controlling air flow velocity therethrough, said regulator means normally closing said secondary air conduit to air flow and adapted to move between a first position wherein said secondary air conduit is substantially closed and a second position wherein said secondary air conduit is substantially open in response to air pressure differentials created in the venturi of said primary air conduit as a patient inhales through the nozzle of said air exit end of said housing; and actuation means operatively connecting said regulator means and said dose introduction means for actuating said dose introduction means when said regulator means first moves from said normally closed first position toward said second position; whereby said regulator means acts to provide a substantially constant maximum air flow velocity through said inhalator by regulating the air flow through said secondary air conduit during inhalation by a patient.
Claim 12
Dependent Claim
59 words
A portable dosage inhalator according to claim 9 wherein said dose introduction means comprises a slide element extending across the bottom of said storage chamber and traversing the venturi of said primary air conduit prior to actuation thereof, said slide element defining a compound receiving aperture therethrough in the portion positioned beneath said storage chamber prior to actuation thereof.
Claim 13
Dependent Claim
32 words
A portable dosage inhalator according to claim 10 wherein said slide element comprises spring means for resiliently urging said slide from said storage chamber to said primary air conduit upon actuation thereof.
Claim 14
Dependent Claim
64 words
A portable dosage inhalator according to claim 9 wherein said regulator means comprises a normally open diaphragm positioned in said secondary air conduit and in fluid communication with the venturi of said primary air conduit, said diaphragm being adapted to contract and thereby open said secondary air conduit to air flow in response to low pressure in the venturi of said primary air conduit.
Claim 15
Dependent Claim
36 words
A portable dosage inhalator according to claim 9 wherein said actuation means comprises a link mounted at one end to said regulator means and the other end thereof adapted to releasably engage said dose introduction means.
Claim 16
Dependent Claim
19 words
A portable dosage inhalator according to claim 9 wherein said housing includes a desiccant in said air inlet end.
Claim 17
Dependent Claim
29 words
A portable dosage inhalator according to claim 9, including a non-return valve mounted between said primary air conduit and the nozzle of said inhalator to prevent reverse air flow.
Claim 18
Dependent Claim
306 words
A portable dosage inhalator for dispensing to a patient a predetermined amount of a pharmacologically active dry powder compound, comprising: a housing defining an air inlet end and an air exit end, said air exit end comprising a nozzle for insertion into the mouth of a patient; storing said compound to be dispensed by said inhalator; a primary air conduit within said housing and defining a venturi therein; a secondary air conduit said primary air conduit; dose introduction means provided within said housing for transporting a predetermined portion of said compound from said storage chamber to said primary air conduit and releasing said compound therein, said dose introduction means adapted to substantially close said primary air conduit to air flow prior to actuation thereof and to allow for air flow through said primary air conduit subsequent to actuation thereof; a normally open diaphragm positioned ins aid secondary air conduit and in fluid communication with the venturi of said primary air conduit for controlling air flow velocity therethrough, said diaphragm normally closing said secondary air conduit to air flow and adapted to contract and thereby to move between a first position wherein said secondary air conduit is substantially closed and a second position wherein said secondary air conduit is substantially open in response to air pressure differentials created in the venturi of said primary air conduit as a patient inhales through the nozzle of said air exit end of said housing; and actuation means operatively connecting said regulator means and said dose introduction means for actuating said dose introduction means when said regulator means first moves from said normally closed first position toward said second position; whereby said diaphragm acts to provide a substantially constant maximum air flow velocity through said inhalator by regulating the air flow through said secondary air conduit during inhalation by a patient.
Claim 19
Dependent Claim
306 words
A portable dosage inhalator for dispensing to a patient a predetermined amount of a pharmacologically active dry powder compound, comprising: a housing defining an air inlet end and an air exit end, said air exit end comprising a nozzle for insertion into the mouth of a patient; storing said compound to be dispensed by said inhalator; a primary air conduit within said housing and defining a venturi therein; a secondary air conduit said primary air conduit; dose introduction means provided within said housing for transporting a predetermined portion of said compound from said storage chamber to said primary air conduit and releasing said compound therein, said dose introduction means adapted to substantially close said primary air conduit to air flow prior to actuation thereof and to allow for air flow through said primary air conduit subsequent to actuation thereof; a normally open diaphragm positioned ins aid secondary air conduit and in fluid communication with the venturi of said primary air conduit for controlling air flow velocity therethrough, said diaphragm normally closing said secondary air conduit to air flow and adapted to contract and thereby to move between a first position wherein said secondary air conduit is substantially closed and a second position wherein said secondary air conduit is substantially open in response to air pressure differentials created in the venturi of said primary air conduit as a patient inhales through the nozzle of said air exit end of said housing; and actuation means operatively connecting said regulator means and said dose introduction means for actuating said dose introduction means when said regulator means first moves from said normally closed first position toward said second position; whereby said diaphragm acts to provide a substantially constant maximum air flow velocity through said inhalator by regulating the air flow through said secondary air conduit during inhalation by a patient.
Claim 20
Dependent Claim
59 words
A portable dosage inhalator according to claim 16 wherein said dose introduction means comprises a slide element extending across the bottom of said storage chamber and traversing the venturi of said primary air conduit prior to actuation thereof, said slide element defining a compound receiving aperture therethrough in the portion positioned beneath said storage chamber prior to actuation thereof.
Claim 21
Dependent Claim
32 words
A portable dosage inhalator according to claim 17 wherein said slide element comprises spring means for resiliently urging said slide from said storage chamber to said primary air conduit upon actuation thereof.
Claim 22
Dependent Claim
35 words
A portable dosage inhalator according to claim 16 wherein said actuation means comprises a link mounted at one end to said diaphragm and the other end thereof adapted to releasably engage said dose introduction means.
Claim 23
Dependent Claim
41 words
A portable dosage inhalator according to claim 19 wherein an air passageway extends between said diaphragm and said primary air conduit to provide fluid communication therebetween, and said link operatively connecting said regulator means and said dose introduction means extends therethrough.
Claim 24
Dependent Claim
19 words
A portable dosage inhalator according to claim 16 wherein said housing includes a desiccant in said air inlet end.
Claim 25
Dependent Claim
29 words
A portable dosage inhalator according to claim 16 including a non-return valve mounted between said primary air conduit and the nozzle of said inhalator to prevent reverse air flow.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-11-10 | 1996-05-11 | 1996-11-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-11-10 | 2000-05-11 | 2000-11-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-11-10 | 2004-05-11 | 2004-11-10 | $7700.00 | Window Closed / Lapsed |