US6638249B1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Ultrasonically actuated needle pump system
Assignee: Wisconsin Alumni Research Foundation
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Filing: 2000-07-17
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Granted: 2003-10-28
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Expires: 2020-07-17
Abstract
Abstract An ultrasonically driven pump, which may be used for sampling body fluids or atomizing liquids, has a stationary outer needle and an inner needle mounted within the bore of the outer needle. The distal end of the inner needle is positioned adjacent to the distal end of the outer needle. The inner needle is ultrasonically vibrated by an ultrasonic actuator without vibrating the outer needle, with resulting draw of liquid through the distal end of the outer needle into the bore of the inner needle for discharge through the proximal end of the inner needle. The outer needle can be formed to have a penetrating tip suited for penetrating the skin of a subject to allow sampling of body fluids including interstitial fluids. The pump can also be used for atomizing liquid, by drawing liquid from a supply that is pumped from the distal end to an open proximal end of the inner needle where the liquid is discharged by atomization into the atmosphere.
Inventors
- 👤 Amit Lal
- 👤 Chung-Hoon Lee
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 05:20
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/145; A61B5/14507; A61B5/1451; A61B5/14514; A61B5/15; A61B5/150007; A61B5/150015; A61B5/150022; A61B5/150053; A61B5/150061; A61B5/150083; A61B5/150206; A61B5/150274; A61B5/150297; A61B5/150374; A61B5/150381; A61B5/150389; A61B5/150503; A61B5/150946; A61B5/150977; A61B5/151; A61B5/15142; A61B10/00; A61B10/0045; A61B2010/008; A61B17/00; A61B2017/00743; A61B2017/00747; A61B2017/00765; A61M; A61M37/00; A61M37/0092
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
77 words
An ultrasonically actuated pump comprising: (a) an outer needle having a distal end and a hollow bore; (b) an inner needle having a hollow bore mounted within the bore of the outer needle and having a distal end positioned adjacent to and spaced inwardly from the distal end of the outer needle and a proximal end; and (c) an ultrasonic actuator, coupled to the inner needle to selectively apply ultrasonic vibrations thereto without vibrating the outer needle.
Claim 2
Dependent Claim
77 words
An ultrasonically actuated pump comprising: (a) an outer needle having a distal end and a hollow bore; (b) an inner needle having a hollow bore mounted within the bore of the outer needle and having a distal end positioned adjacent to and spaced inwardly from the distal end of the outer needle and a proximal end; and (c) an ultrasonic actuator, coupled to the inner needle to selectively apply ultrasonic vibrations thereto without vibrating the outer needle.
Claim 3
Dependent Claim
26 words
The ultrasonically actuated pump of claim 1 wherein the distal end of the outer needle is cut at a bias to form a skin penetrating tip.
Claim 4
Dependent Claim
42 words
The ultrasonically actuated pump of claim 1 further including a base to which the outer needle is fixed, and supports coupling the inner needle to the base without transmission of vibrations from the inner needle through the base to the outer needle.
Claim 5
Dependent Claim
15 words
The ultrasonically actuated pump of claim 1 wherein the ultrasonic actuator comprises a piezoelectric transducer.
Claim 6
Dependent Claim
16 words
The ultrasonically actuated pump of claim 4 wherein the piezoelectric transducer comprises a PZT ceramic plate.
Claim 7
Dependent Claim
49 words
The ultrasonically actuated pump of claim 1 wherein the outer needle is a tube of a material selected from the group consisting of a metal, glass, and silicon, and the inner needle is a capillary tube of a material selected from the group consisting of glass, metal, and silicon.
Claim 8
Dependent Claim
153 words
An ultrasonically actuated pump comprising: (a) an outer needle having a distal end and a hollow bore, wherein the outer needle comprises a penetrating tip; (b) an inner needle having a hollow bore mounted within the bore of the outer needle and having a distal end positioned adjacent to the distal end of the outer needle and a proximal end; (c) an ultrasonic actuator, coupled to the inner needle to selectively apply ultrasonic vibrations thereto without vibrating the outer needle; and (d) a silicon base to which the outer needle is fixed, and a silicon horn formed to concentrate ultrasonic energy at a tip of the horn, wherein the inner needle is bonded to the silicon horn to vibrate therewith, and wherein the ultrasonic actuator is bonded to the silicon horn, such that actuation of the ultrasonic actuator drives vibrations in the silicon horn which are transmitted to the inner needle bonded thereto.
Claim 9
Dependent Claim
153 words
An ultrasonically actuated pump comprising: (a) an outer needle having a distal end and a hollow bore, wherein the outer needle comprises a penetrating tip; (b) an inner needle having a hollow bore mounted within the bore of the outer needle and having a distal end positioned adjacent to the distal end of the outer needle and a proximal end; (c) an ultrasonic actuator, coupled to the inner needle to selectively apply ultrasonic vibrations thereto without vibrating the outer needle; and (d) a silicon base to which the outer needle is fixed, and a silicon horn formed to concentrate ultrasonic energy at a tip of the horn, wherein the inner needle is bonded to the silicon horn to vibrate therewith, and wherein the ultrasonic actuator is bonded to the silicon horn, such that actuation of the ultrasonic actuator drives vibrations in the silicon horn which are transmitted to the inner needle bonded thereto.
Claim 10
Dependent Claim
206 words
An ultrasonically actuated pump comprising: (a) an outer needle having a distal end and a hollow bore, wherein the outer needle comprises a penetrating tip; (b) an inner needle having a hollow bore mounted within the bore of the outer needle and having a distal end positioned adjacent to the distal end of the outer needle and a proximal end; (c) an ultrasonic actuator, coupled to the inner needle to selectively apply ultrasonic vibrations thereto without vibrating the outer needle; and (d) a silicon base to which the outer needle is fixed, and a silicon horn formed to concentrate ultrasonic energy at a tip of the horn, wherein the inner needle is bonded to the silicon horn to vibrate therewith, and wherein the ultrasonic actuator is bonded to the silicon horn, such that actuation of the ultrasonic actuator drives vibrations in the silicon horn which are transmitted to the inner needle bonded thereto; wherein the silicon base and the silicon horn are formed from a unitary piece of crystalline silicon and are joined together by connectors extending between the base and the silicon horn at a node of vibration in the silicon horn so that vibrations of the horn are not substantially transmitted to the base.
Claim 11
Dependent Claim
206 words
An ultrasonically actuated pump comprising: (a) an outer needle having a distal end and a hollow bore, wherein the outer needle comprises a penetrating tip; (b) an inner needle having a hollow bore mounted within the bore of the outer needle and having a distal end positioned adjacent to the distal end of the outer needle and a proximal end; (c) an ultrasonic actuator, coupled to the inner needle to selectively apply ultrasonic vibrations thereto without vibrating the outer needle; and (d) a silicon base to which the outer needle is fixed, and a silicon horn formed to concentrate ultrasonic energy at a tip of the horn, wherein the inner needle is bonded to the silicon horn to vibrate therewith, and wherein the ultrasonic actuator is bonded to the silicon horn, such that actuation of the ultrasonic actuator drives vibrations in the silicon horn which are transmitted to the inner needle bonded thereto; wherein the silicon base and the silicon horn are formed from a unitary piece of crystalline silicon and are joined together by connectors extending between the base and the silicon horn at a node of vibration in the silicon horn so that vibrations of the horn are not substantially transmitted to the base.
Claim 12
Dependent Claim
45 words
The ultrasonically actuated pump of claim 1 wherein the proximal end of the inner needle is open to the atmosphere so that liquid pumped from the distal end of the inner needle to its proximal end is atomized into the atmosphere at the proximal end.
Claim 13
Dependent Claim
24 words
The ultrasonically actuated pump of claim 1 wherein the outside diameter of the outer needle is less than or equal to about 600 micrometers.
Claim 14
Dependent Claim
32 words
The ultrasonically actuated pump of claim 1 wherein the ultrasonic actuator is a piezoelectric transducer, and further including an electrical power driver connected to supply oscillating electrical power to the piezoelectric transducer.
Claim 15
Dependent Claim
117 words
An ultrasonically actuated pump comprising: (a) a plurality of parallel outer needles mounted together to a mounting plate, each outer needle having a hollow bore and a distal end at a position spaced away from the mounting plate; (b) a plurality of inner needles, each inner needle mounted within the bore of an outer needle and free to vibrate with respect to the outer needle, each inner needle having a hollow bore, a proximal end, and a distal end positioned adjacent to the distal end of the outer needle in which it is mounted; (c) an ultrasonic actuator coupled to the inner needles to selectively vibrate the inner needles at ultrasonic frequencies without vibrating the outer needles.
Claim 16
Dependent Claim
117 words
An ultrasonically actuated pump comprising: (a) a plurality of parallel outer needles mounted together to a mounting plate, each outer needle having a hollow bore and a distal end at a position spaced away from the mounting plate; (b) a plurality of inner needles, each inner needle mounted within the bore of an outer needle and free to vibrate with respect to the outer needle, each inner needle having a hollow bore, a proximal end, and a distal end positioned adjacent to the distal end of the outer needle in which it is mounted; (c) an ultrasonic actuator coupled to the inner needles to selectively vibrate the inner needles at ultrasonic frequencies without vibrating the outer needles.
Claim 17
Dependent Claim
45 words
The ultrasonically actuated pump of claim 12 wherein each of the inner needles are secured to a vibration transmitting plate, and wherein the ultrasonic actuator is at least one piezoelectric transducer bonded to the vibration transmitting plate to transmit vibrations therethrough to the inner needles.
Claim 18
Dependent Claim
46 words
The ultrasonically actuated pump of claim 13 further including spacers between the mounting plate for the outer needles and the vibration transmitting plate for the inner needles to secure the two plates together without substantially transmitting vibrations from the vibration transmitting plate to the mounting plate.
Claim 19
Dependent Claim
26 words
The ultrasonically actuated pump of claim 12 wherein the distal end of each outer needle is cut at a bias to form a skin penetrating tip.
Claim 20
Dependent Claim
15 words
The ultrasonically actuated pump of claim 12 wherein the ultrasonic actuator comprises a piezoelectric transducer.
Claim 21
Dependent Claim
16 words
The ultrasonically actuated pump of claim 16 wherein the piezoelectric transducer comprises a PZT ceramic plate.
Claim 22
Dependent Claim
28 words
The ultrasonically actuated pump of claim 12 wherein each outer needle is formed of a metal tube and each inner needle is formed of a glass capillary tube.
Claim 23
Dependent Claim
45 words
The ultrasonically actuated pump of claim 12 wherein the proximal end of each inner needle is open to the atmosphere so that liquid pumped from the distal end of each inner needle to its proximal end is atomized into the atmosphere at the proximal end.
Claim 24
Dependent Claim
32 words
The ultrasonically actuated pump of claim 12 wherein the ultrasonic actuator is a piezoelectric transducer, and further including an electrical power driver connected to supply oscillating electrical power to the piezoelectric transducer.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2006-10-27 | 2007-04-28 | 2007-10-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2010-10-27 | 2011-04-28 | 2011-10-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2014-10-27 | 2015-04-28 | 2015-10-28 | $7700.00 | Window Closed / Lapsed |