US6544223B1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Balloon catheter for delivering therapeutic agents
Assignee: Abbott Cardiovascular Systems Inc
•
Filing: 2001-01-05
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Granted: 2003-04-08
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Expires: 2021-01-05
Abstract
Abstract A drug delivery device for delivering therapeutic agents and method of making such a device. The device including an inflatable balloon having a plurality of holes formed in the wall of the balloon. A microporous coating covers a portion of the outer surface of the wall of the balloon. The thickness of the coating and the size of the micropores can permit controlled delivery of a substance from the micropores of the coating and into the tissue of a patient's lumen.
Inventors
- 👤 Lyudmila Kokish
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:20
CPC Classifications
A; A61; A61L; A61L29/00; A61L29/08; A61L29/085; A61L29/14; A61L29/146; A61L29/16; A61M; A61M25/00; A61M25/10; A61L2300/00; A61L2300/60; A61L2300/606; A61M2025/1043; A61M2025/105; A61M2025/1086
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
141 words
A drug delivery device, comprising: an elongated shaft having a distal section and a proximal section; an inflation assembly coupled to said distal section of said elongated shaft, said inflation assembly including an inflatable balloon having a plurality of holes defined in a wall of said balloon; and a microporous precipitate coating, wherein a majority of the inner surface of said microporous precipitate coating is in intimate contact with a majority of the outer surface of said balloon wall so as not to include a gap between said microporous precipitate coating and said balloon wall, and wherein said microporous precipitate coating has micropores of a size that permit controlled delivery of a drug from said elongated shaft to said holes in said balloon and through said micropores of said microporous precipitate coating disposed on the outer surface of said balloon wall.
Claim 2
Dependent Claim
141 words
A drug delivery device, comprising: an elongated shaft having a distal section and a proximal section; an inflation assembly coupled to said distal section of said elongated shaft, said inflation assembly including an inflatable balloon having a plurality of holes defined in a wall of said balloon; and a microporous precipitate coating, wherein a majority of the inner surface of said microporous precipitate coating is in intimate contact with a majority of the outer surface of said balloon wall so as not to include a gap between said microporous precipitate coating and said balloon wall, and wherein said microporous precipitate coating has micropores of a size that permit controlled delivery of a drug from said elongated shaft to said holes in said balloon and through said micropores of said microporous precipitate coating disposed on the outer surface of said balloon wall.
Claim 3
Dependent Claim
32 words
The device of claim 1 , wherein said holes are laser drilled with a diameter in a range from approximately 0.01 mm to 0.1 mm (3.94×10 −4 inch to 3.94×10 −3 inch).
Claim 4
Dependent Claim
29 words
The device of claim 1 , wherein said size of said micropores is in a range from approximately 0.001 mm (3.94×10 −5 inch) to 0.020 mm (7.87×10 −4 inch).
Claim 5
Dependent Claim
31 words
The device of claim 1 , wherein a thickness of said microporous precipitate coating is in a range from approximately 0.005 mm (1/97×10 −4 inch) to 0.020 mm (7.87×10 −4 inch).
Claim 6
Dependent Claim
18 words
The device of claim 1 , wherein said microporous precipitate coating is made using phase inversion precipitation techniques.
Claim 7
Dependent Claim
21 words
The device of claim 1 , wherein said microporous precipitate coating is formed from a polymer, a solvent and a non-solvent.
Claim 8
Dependent Claim
20 words
The device of claim 6 , wherein said polymer is taken from the group consisting of silicones, polyesters and polyurethanes.
Claim 9
Dependent Claim
23 words
The device of claim 6 , wherein said solvent is taken from the group consisting of: tetrahydrofuran (THF), dimethylacetamide, dimethylformamide, dimethylsulfoxide and dioxane.
Claim 10
Dependent Claim
11 words
The device of claim 6 , wherein said non-solvent is water.
Claim 11
Dependent Claim
30 words
The device of claim 1 , wherein said drug is taken from the group consisting of: antithrombotics, antiproliferatives, anti-inflammatory agents, smooth muscle cell migration inhibitors, reendothelialization agents and restenosis-reducing drugs.
Claim 12
Dependent Claim
88 words
A drug delivery system comprising: a catheter having a distal section and a proximal section; an inflatable balloon integrated with said distal section of said catheter, said balloon having a plurality of holes for delivering a drug to a body vessel; and a microporous precipitate of a polymer disposed on a portion of the surface of said balloon, said precipitate covering at least a portion of said holes and having micropores of a size that permit controlled delivery of a drug from said holes to said body vessel.
Claim 13
Dependent Claim
88 words
A drug delivery system comprising: a catheter having a distal section and a proximal section; an inflatable balloon integrated with said distal section of said catheter, said balloon having a plurality of holes for delivering a drug to a body vessel; and a microporous precipitate of a polymer disposed on a portion of the surface of said balloon, said precipitate covering at least a portion of said holes and having micropores of a size that permit controlled delivery of a drug from said holes to said body vessel.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2006-04-07 | 2006-10-07 | 2007-04-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2010-04-07 | 2010-10-07 | 2011-04-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2014-04-07 | 2014-10-07 | 2015-04-08 | $7700.00 | Window Closed / Lapsed |