US6517534B1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Peri-urethral ablation
Assignee: COSMAN COMPANY Inc
•
Filing: 1999-08-15
•
Granted: 2003-02-11
•
Expires: 2019-08-15
Abstract
Abstract Relief of urethral obstruction is achieved by heat ablation of prostatic tissue by an ablation probe passed within the urethra to a position in the prostate near the point of urethral obstruction. The probe is coupled to a power supply to deliver power to tissue near the probe and thus to ablatively heat the urethra and the prostatic tissue near the urethra. The temperature of the tissue is sensed at the probe to control the heating and ablation process. In one embodiment, the probe has a blunt tip to help prevent piercing of the wall of the urethra during insertion of the probe into the urethra through the penis and the positioning of the probe tip near to the point of urethral obstruction. Several forms of probes, apparatus, and methods accommodate the specific objectives.
Inventors
- 👤 Francis J. McGovern
- 👤 S. Nahum Goldberg
- 👤 Eric R. Cosman
- 👤 William J. Rittman, III
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 23:12
CPC Classifications
A; A61; A61B; A61B18/00; A61B18/04; A61B18/12; A61B18/14; A61B18/1485; A61B18/08; A61B18/1477; A61B18/18; A61B18/1815; A61B2018/00005; A61B2018/00053; A61B2018/00059; A61B2018/00071; A61B2018/00083; A61B2018/00214; A61B2018/0022; A61B2018/0025; A61B2018/00261; A61B2018/00315; A61B2018/00505; A61B2018/00517; A61B2018/00547; A61B2018/00553; A61B2018/00571; A61B2018/00577; A61B2018/00636; A61B2018/00666; A61B2018/00678; A61B2018/00696; A61B2018/00702; A61B2018/00755; A61B2018/00773; A61B2018/00791; A61B2018/00797; A61B2018/00815; A61B2018/00821; A61B2018/00875; A61B18/1206; A61B2018/1246; A61B2018/1253; A61B2018/1405; A61B2018/1425; A61B2018/1467; A61B90/00; A61B90/36; A61B90/37; A61B2090/378; A61B2090/3782; A61B2218/00; A61B2218/001; A61B2218/002; A61B2218/007
Claims Analysis
Total Claims: 28
Claim 1
Independent Claim
208 words
A method of relieving urethral obstruction in a patient having a urethra, a prostate and a bladder, the method comprising the steps of: providing a catheter including: a plurality of ring electrodes on an external surface of the catheter in a flexible region of the catheter configured and arranged to substantially maintain flexibility in the region, and an inflatable balloon proximate to a distal end of the catheter wherein the inflatable balloon may be inflated by injection of fluid through a port in the catheter; inserting the catheter into the urethra of the patient a distance sufficient to provide contact between the electrodes and at least a portion of the urethra and to insert the balloon into the bladder of the patient; inflating the balloon; positioning the electrodes within the urethra of the patient at a location in the prostate where urethral enlargement is desired; and applying a high-frequency signal to at least one of the electrodes to elevate the temperature to at least 50° C. and induce heat ablation of at least a portion of the urethra wall and at least a portion of periurethral tissue in the patient, thereby inducing ablative reduction of tissue mass of the urethra and nearby tissue to reduce the urethral obstruction.
Claim 2
Independent Claim
208 words
A method of relieving urethral obstruction in a patient having a urethra, a prostate and a bladder, the method comprising the steps of: providing a catheter including: a plurality of ring electrodes on an external surface of the catheter in a flexible region of the catheter configured and arranged to substantially maintain flexibility in the region, and an inflatable balloon proximate to a distal end of the catheter wherein the inflatable balloon may be inflated by injection of fluid through a port in the catheter; inserting the catheter into the urethra of the patient a distance sufficient to provide contact between the electrodes and at least a portion of the urethra and to insert the balloon into the bladder of the patient; inflating the balloon; positioning the electrodes within the urethra of the patient at a location in the prostate where urethral enlargement is desired; and applying a high-frequency signal to at least one of the electrodes to elevate the temperature to at least 50° C. and induce heat ablation of at least a portion of the urethra wall and at least a portion of periurethral tissue in the patient, thereby inducing ablative reduction of tissue mass of the urethra and nearby tissue to reduce the urethral obstruction.
Claim 3
Dependent Claim
22 words
The method of claim 1 wherein applying the signal includes enlarging the passageway relative to a normal size of the urethral passage.
Claim 4
Dependent Claim
24 words
The method of claim 1 wherein applying the signal includes applying the output through at least one of the electrodes to a return electrode.
Claim 5
Dependent Claim
20 words
The method of claim 1 including selecting one or more electrodes to be energized to grade a size of ablation.
Claim 6
Dependent Claim
17 words
The method of claim 1 wherein applying the signal includes energizing the electrodes in a bi-polar configuration.
Claim 7
Dependent Claim
27 words
The method of claim 1 wherein the step of providing includes at least one of the plurality of electrodes having a length greater than about 1 cm.
Claim 8
Dependent Claim
21 words
The method of claim 1 further comprising thereafter applying the high-frequency signal to a second electrode of the plurality of electrodes.
Claim 9
Independent Claim
105 words
A method of treating the urethral passage, comprising: placing a distal portion of an elongate member intraurethrally into the urethral passage, a flexible region of the distal portion of the elongate member having a plurality of ring electrodes on an external surface of a catheter configured and arranged to substantially maintain flexibility in the region, and energizing at least one of the electrodes with high frequency energy to elevate the temperature to at least 50° C. and ablate tissue of at least a portion of a wall defining the urethral passage and ablate adjacent prostate tissue to form a cavity communicating with the urethral passage.
Claim 10
Independent Claim
105 words
A method of treating the urethral passage, comprising: placing a distal portion of an elongate member intraurethrally into the urethral passage, a flexible region of the distal portion of the elongate member having a plurality of ring electrodes on an external surface of a catheter configured and arranged to substantially maintain flexibility in the region, and energizing at least one of the electrodes with high frequency energy to elevate the temperature to at least 50° C. and ablate tissue of at least a portion of a wall defining the urethral passage and ablate adjacent prostate tissue to form a cavity communicating with the urethral passage.
Claim 11
Dependent Claim
35 words
The method of claim 8 wherein energizing at least one of the electrodes forms a cavity in the wall and adjacent prostate tissue having a diameter in the range of about 0.3 to 5 cm.
Claim 12
Dependent Claim
29 words
The method of claim 8 wherein energizing at least one of the electrodes elevates a temperature of the wall and adjacent prostate tissue to about 50 to 100° C.
Claim 13
Dependent Claim
21 words
The method of claim 10 wherein energizing at least one of the electrodes includes elevating the temperature for about six minutes.
Claim 14
Dependent Claim
22 words
The method of claim 8 wherein energizing at least one of the electrodes includes connecting the electrode to a high frequency generator.
Claim 15
Dependent Claim
33 words
The method of claim 8 wherein energizing at least one of the electrodes includes forming the cavity such that the urethral passage is enlarged relative to a normal size of the urethral passage.
Claim 16
Dependent Claim
30 words
The method of claim 8 wherein energizing at least one of the electrodes includes applying the high frequency energy through at least one of the electrodes to a return electrode.
Claim 17
Dependent Claim
17 words
The method of claim 8 further comprising imaging the electrodes to monitor the position of the electrodes.
Claim 18
Dependent Claim
10 words
The method of claim 15 wherein imaging includes ultrasonic imaging.
Claim 19
Dependent Claim
13 words
The method of claim 16 wherein imaging includes inserting an ultrasonic scanner transrectally.
Claim 20
Dependent Claim
10 words
The method of claim 15 wherein imaging includes CT imaging.
Claim 21
Dependent Claim
10 words
The method of claim 15 wherein imaging includes MR imaging.
Claim 22
Dependent Claim
16 words
The method of claim 8 further comprising detecting a temperature level of tissue surrounding the electrodes.
Claim 23
Dependent Claim
20 words
The method of claim 8 including selecting one or more electrodes to be energized to grade a size of ablation.
Claim 24
Dependent Claim
21 words
The method of claim 8 wherein energizing at least one of the electrodes includes energizing the electrodes in a bi-polar configuration.
Claim 25
Dependent Claim
27 words
The method of claim 8 wherein the step of providing includes at least one of the plurality of electrodes having a length greater than about 1 cm.
Claim 26
Dependent Claim
21 words
The method of claim 8 further comprising thereafter energizing a second electrode of the plurality of electrodes with the high-frequency signal.
Claim 27
Independent Claim
111 words
A method of treating the urethral passage, comprising: placing a distal portion of an elongate member intraurethrally into the urethral passage, a flexible region of the distal portion of the elongate member having a plurality of ring electrodes on an external surface of a catheter configured and arranged to substantially maintain flexibility in the region, each electrode being a non-cooled electrode, and energizing at least one of the electrodes with high frequency energy to elevate the temperature to at least 50° C. and ablate tissue of at least a portion of a wall defining the urethral passage and ablate adjacent prostate tissue to form a cavity communicating with the urethral passage.
Claim 28
Independent Claim
111 words
A method of treating the urethral passage, comprising: placing a distal portion of an elongate member intraurethrally into the urethral passage, a flexible region of the distal portion of the elongate member having a plurality of ring electrodes on an external surface of a catheter configured and arranged to substantially maintain flexibility in the region, each electrode being a non-cooled electrode, and energizing at least one of the electrodes with high frequency energy to elevate the temperature to at least 50° C. and ablate tissue of at least a portion of a wall defining the urethral passage and ablate adjacent prostate tissue to form a cavity communicating with the urethral passage.
References Cited (Backward Citations)
US2407690A
Cited
US4116198A
Cited
US4184492A
Cited
US4411266A
Cited
US4682596A
Cited
US4785823A
Cited
US5061266A
Cited
US5178620A
Cited
US4967765A
Cited
US5220927A
Cited
US5249585A
Cited
US5112330A
Cited
US5509929A
Cited
WO1991013650A1
Cited
US5480417A
Cited
US5454809A
Cited
US4979948A
Cited
US5007437A
Cited
US5263931A
Cited
US5257977A
Cited
US5301687A
Cited
US5492529A
Cited
US5810764A
Cited
US5697909A
Cited
US5681282A
Cited
US5304214A
Cited
US5330518A
Cited
US5545137A
Cited
US5620480A
Cited
US5370677A
Cited
US5300099A
Cited
US5755754A
Cited
US5277201A
Cited
US5322507A
Cited
US5599294A
Cited
US5542915A
Cited
US5370675A
Cited
US5733315A
Cited
US5545161A
Cited
US5348554A
Cited
US5486161A
Cited
US5403311A
Cited
US5520684A
Cited
US5464437A
Cited
US6171306B1
Cited
US5472441A
Cited
US5599346A
Cited
WO1996000039A1
Cited
WO1996000036A1
Cited
US5630426A
Cited
WO1996037158A1
Cited
WO1996034571A1
Cited
US5645528A
Cited
US5628770A
Cited
US5849011A
Cited
WO1997000646A1
Cited
WO1997000647A1
Cited
EP0754437A2
Cited
US5733316A
Cited
WO1997028840A1
Cited
US5944715A
Cited
US5891134A
Cited
WO1998027881A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2006-02-10 | 2006-08-12 | 2007-02-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2010-02-10 | 2010-08-12 | 2011-02-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2014-02-10 | 2014-08-12 | 2015-02-11 | $7700.00 | Window Closed / Lapsed |